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Tablet for treating chronic colitis

A chronic colitis and tablet technology, applied in the field of tablets and tablets for the treatment of chronic colitis, can solve the problems of long course of metronidazole, hypoadrenalism, and reduced efficacy.

Inactive Publication Date: 2010-07-07
BEIJING ZHONGKE RENHE SCI & TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Among them, Western medicine mainly includes sulfasalazine, antibiotics, metronidazole, hormones, azathioprine and antibacterial drugs, etc. These drugs can relieve symptoms to varying degrees, but due to side effects, it is difficult for patients to adhere to long-term medication
For example, headache, anorexia, nausea, vomiting, general malaise, rash, neutropenia, aplastic anemia, or autoimmune hemolysis are likely to occur when sulfasalazine is used; antibiotics should not be used for a long time; metronidazole has a great curative effect on patients with a long course of disease Reduced; long-term use of hormones can cause acne, hirsutism, full moon face, central obesity, and easily induce hypertension and diabetes, and can also affect phosphorus metabolism, resulting in osteoporosis and even aseptic necrosis of the femoral head. Decreased, decreased ability to resist infection
Due to the toxic and side effects of western medicine, in recent years, the research on the treatment of colonic inflammation with traditional Chinese medicine has been paid more attention. Although there are some traditional Chinese medicine preparations for the treatment of this disease, the curative effect is not good.

Method used

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  • Tablet for treating chronic colitis
  • Tablet for treating chronic colitis
  • Tablet for treating chronic colitis

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0061] The following raw material combinations are used:

[0062] Codonopsis 55g Woody Fragrance 25g Guizhi 50g

[0063] Yanhu Suo 80g Rhubarb 70g Psoralen 100g

[0064] Paeoniae Alba 60g Pueraria 80g Ginger 30g

[0065] 25g jujube and 50g roasted licorice.

[0066] Its preparation process comprises the following steps:

[0067] (1) Take 25g of Muxiang and 50g of Cinnamon Twig, grind them into coarse powder, mix them, steam distill to extract the volatile oil, wrap them with β-cyclodextrin, freeze-dry, and set aside;

[0068] (2) Take 55g of Codonopsis pilosula, 80g of Corydalis Corydalis, 70g of rhubarb, and 80g of Pueraria lobata root, grind them into coarse powder, mix them, add ethanol to reflux and extract 3 times, each time for 1 hour, filter (medicine dregs for later use), and depressurize the filtrate to recover ethanol to extract , dried, pulverized, sieved to obtain fine powder of alcohol extract, set aside;

[0069] (3) Mix the above-mentioned ethanol-extracted...

Embodiment 2

[0072] The following raw material combinations are used:

[0073] Codonopsis 25g Woody Fragrance 20g Guizhi 35g

[0074] Corydalis 60g Rhubarb 40g Psoralen 60g

[0075] Paeoniae Alba 30g Pueraria 50g Ginger 20g

[0076] 12g jujube and 40g roasted licorice.

[0077] Its preparation process comprises the following steps:

[0078] (1) Grind Muxiang and Guizhi into coarse powder, mix them, steam distill to extract the volatile oil, enclose with β-cyclodextrin, freeze-dry, and set aside;

[0079] (2) Take Codonopsis pilosula, Corydalis Corydalis, rhubarb, and kudzu root, crush them into coarse powder, mix them, add ethanol to reflux and extract twice, each time for 1 hour, filter (medicine dregs for later use), and depressurize the filtrate to recover ethanol to extract, dry, and pulverize , sieved to obtain alcohol extract fine powder, set aside;

[0080] (3) Mix the above-mentioned ethanol-extracted medicinal residue with other five flavors such as psoralen, add water to dec...

Embodiment 3

[0083] The following raw material combinations are used:

[0084] Codonopsis 80g Woody Fragrance 40g Guizhi 65g

[0085] Yanhusuo 100g rhubarb 100g psoralen 120g

[0086] Paeoniae Alba 85g Pueraria 110g Ginger 35g

[0087] 30g jujube and 70g roasted licorice.

[0088] Its preparation process comprises the following steps:

[0089] (1) Grind Muxiang and Guizhi into coarse powder, mix them, steam distill to extract the volatile oil, enclose with β-cyclodextrin, freeze-dry, and set aside;

[0090] (2) Take Codonopsis pilosula, Corydalis Corydalis, rhubarb, and kudzu root, grind them into coarse powder, mix them, add ethanol to reflux and extract 4 times, each time for 1 hour, filter (medicine dregs for later use), and decompress the filtrate to recover ethanol to extract, dry, and grind , sieved to obtain alcohol extract fine powder, set aside;

[0091] (3) Mix the above-mentioned ethanol-extracted medicinal dregs with other five flavors such as psoralen, add water to decoct...

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Abstract

The invention discloses a tablet for treating chronic colitis, belonging to the field of the Chinese herba preparation technology; the tablet is formed by eleven Chinese medicinal crops, that is, codonopsis pilosula, elecampane, cassia twig, corydalis tuber, rhubarb, fructus psoraleae, radix paeoniae alba, the root of kudzu vine, ginger, Chinese date and radix glycyrrhizae preparata, and the Radix Glycyrrhizae Preparata are prepared into the tablets by a conventional processing technology by weight proportion; the tablet has the functions of tonifying spleen and kidney, clearing away heat and toxic material, regulating vital energy and alleviating pain and treating diarrhea with astringents, and is mainly treating chronic colitis; in addition, after the animal pharmacological testing research, the tablet is proved to have antidiarrheic and anti-inflammatory functions and good abirritation.

Description

technical field [0001] The invention belongs to the technical field of traditional Chinese medicine preparations, relates to a tablet, in particular to a tablet for treating chronic colitis. Background technique [0002] Chronic colitis, an autoimmune disease, is an inflammatory disease of unknown cause in the rectum and colon. The onset of this disease is mostly slow, the course of the disease is chronic, protracted for several years to more than ten years, there are often periods of attack and remission or the persistence is gradually aggravated, and occasionally acute outbreaks, the main clinical manifestations are diarrhea, mucus pus and blood in the stool, abdominal pain and Tenesmus, varying in severity, often recurrent. The depth of the invasion of this disease is mainly the mucosa and submucosa. There is extensive congestion and hemorrhage on the surface of the mucosa, and the mucosa is granular and crisp. There are many erosions and ulcers on the surface of the muc...

Claims

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Application Information

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IPC IPC(8): A61K36/9068A61K9/20A61P1/00
Inventor 颜丽君
Owner BEIJING ZHONGKE RENHE SCI & TECH
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