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Preparation method of emergency survival hemostatic based on natural zeolite in Jinyun of Zhejiang

A technology of natural zeolite and hemostatic agent, which is applied in the field of preparation of emergency life-saving hemostatic agent, to achieve improved hemostatic performance, good hemostatic effect, and no skin irritation

Inactive Publication Date: 2011-04-06
范杰
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

So far, there are no domestic and foreign patent reports on the application of Zhejiang Jinyun natural zeolite in blood coagulation materials, wound treatment and trauma repair, or the combination of Zhejiang Jinyun natural zeolite with medical bandages and medical adhesives for trauma repair

Method used

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  • Preparation method of emergency survival hemostatic based on natural zeolite in Jinyun of Zhejiang
  • Preparation method of emergency survival hemostatic based on natural zeolite in Jinyun of Zhejiang
  • Preparation method of emergency survival hemostatic based on natural zeolite in Jinyun of Zhejiang

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Effect test

Embodiment 1

[0037] The present invention selects Zhejiang Jinyun natural zeolite as raw material, and the XRD collection of illustrative plates of Zhejiang Jinyun natural clinoptilolite sees attached figure 1 , SEM image see image 3 ; The original powder of Jinyun natural mordenite, and the XRD patterns after acid treatment, roasting and ammonification are shown in the attached figure 2 , the SEM image is attached Figure 4 .

[0038] A certain amount of Jinyun natural zeolite is put into a traditional Chinese medicine pulverizer, and the pulverization time is about 5 minutes; the particle size obtained after pulverization is 1 micron to 1 mm. The crushed natural zeolite was dried in an oven at 100° C. for 1 h. Its hemostatic effect is similar to that of Quikclot, see attached Figure 5 .

Embodiment 2

[0040] The modified sodium-type natural zeolite and CaCl with a concentration of 1.0mol / L 2 Mix according to the solid-to-liquid ratio of 1g / 20ml, react at room temperature for 24h, wash with deionized water until there is no Ca in the solution 2+ , and dried in an oven at 100 °C for 24 h to obtain the modified calcium-rich natural clinoptilolite. See attached for its hemostatic effect Image 6 .

Embodiment 3

[0042] Take 5.0g of natural zeolite and mix it with a certain amount of water for 1 hour, then filter it with suction, wash it, and dry it at 100°C for 24 hours. The water-washed natural mordenite and natural clinoptilolite are obtained, wherein the water-soluble components are reduced, and the magnetic substances are also reduced. Its hemostatic effect is similar to that of Quikclot, see attached Image 6 .

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Abstract

The invention discloses a preparation method of an emergency survival hemostatic based on natural zeolite in Jinyun of Zhejiang. The emergency survival hemostatic takes natural clinoptilolite and natural mordenite in Jinyun of Zhejiang Province as raw materials and comprises main components of monox, titanium oxide, alumina, ferric oxide, magnesia, calcium oxide, sodium oxide, potassium oxide and the like. The emergency survival hemostatic can be used for different medical occasions to stanch bleeding, can be used for preparing band aids, transfusion plasters, self-adhesion dressing, first-aid packets and the like by being mechanically combined with other medical materials and medical instruments. Meanwhile, bacteriophage, anodyne and the like can be adsorbed in the emergency survival hemostatic by using the ion exchange characteristic of the emergency survival hemostatic; the emergency survival hemostatic can be used as a medical transmission carrier; and other ions can be loaded by using the ion exchange characteristic of the emergency survival hemostatic, thereby better curative effect can be obtained. The emergency survival hemostatic based on natural zeolite in Jinyun of Zhejiang has the advantages of high stanching speed, low heat release, asepsis, apyrogeneity, non-cytotoxicity, no sensitivity response, harmlessness to skin, no reducing substances, no acid-base excitability and low cost, can extract content heavy metal with extremely-low content and is convenient for use.

Description

technical field [0001] The invention relates to a preparation method of an emergency life-saving hemostatic agent, in particular to a preparation method of Zhejiang Jinyun natural zeolite hemostatic agent used for treating fatal large-vessel hemorrhage uncontrollable by conventional hemostatic measures. [0002] Background technique [0003] Emergency life-saving hemostatic agent is an emerging research field in the world. Emergency life-saving hemostats are primarily developed for emergencies where bleeding does not stop in trauma. Emergency situations like aortic bleeding can be controlled in a short time (3 minutes), gaining precious time for further medical treatment. [0004] According to the statistics of the Ministry of Health in 2002, trauma and poisoning ranked fifth among the top ten causes of death, and the number of people who lost their lives every year was as high as 9.5 million. Excessive blood loss is the single largest contributor to trauma death, with ap...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K33/26A61K33/00A61P7/04A61K33/24A61K33/08
Inventor 范杰李云龙李辉
Owner 范杰
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