Pharmaceutical composition comprising risedronic acid or a salt thereof and vitamin D

A technology of risedronic acid and its composition, which is applied in the field of pharmaceutical compositions containing risedronic acid or its salt and vitamin D, and can solve problems such as difficulty in ensuring content balance, lack of specific disclosure, and low stability of dosage forms , to achieve excellent stability, enhance homeostasis, and inhibit bone resorption
CN102149387AInactive Publication Date: 2011-08-10HANLIM PHARMA CO LTD
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Patent Information

Authority / Receiving Office
CN · China
Current Assignee / Owner
HANLIM PHARMA CO LTD
Publication Date
2011-08-10
Estimated Expiration
Not applicable · inactive patent

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Abstract

The present invention provides a pharmaceutical composition for preventing or treating osteoporosis, comprising risedronic acid or a salt thereof and vitamin D. Further, the present invention provides an oral tablet obtained by tableting a mixture of risedronic acid or a salt thereof and granular vitamin D; and an oral capsule obtained by uniformly distributing risedronic acid or a salt thereof and vitamin D among the mixed solvent of soybean oil and hydrogenated coconut palm oil and filling a capsule with the resultant material.
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Description

technical field

[0001] The invention relates to a pharmaceutical composition containing risedronic acid or its salt and vitamin D, which is used for preventing or treating osteoporosis. The invention also relates to an oral tablet and a capsule capable of maintaining the balance and stability of the contents of risdronic acid or its salt and vitamin D. Background technique

[0002] The chemical name of risedronic acid is 2-(3-pyridyl)-1-hydroxyethane-1,1-bisphosphonic acid, which is used for the treatment and prevention of postmenopausal osteoporosis and Drugs used to maintain or enhance bone density in male and female patients receiving long-term corticosteroid treatment (systemic corticosteroid treatment). It is known that risedronic acid has salts in various forms including risedronate sodium, and risedronate sodium can exist in various forms such as anhydrate, monohydrate, and 2.5 hydrate, and has multiple A polymorph (International Patent Publication No. WO2003 / 086355...

Claims

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