Turbot pathogenic strain and inactivated vaccine for ascites disease

Abstract

The invention discloses a turbot pathogenic strain which is Acinetobacter lwoffii, wherein the collection number of the strain is CCTCC (China center for type culture collection) NO:M2010372. The screened Acinetobacter lwoffii is used for preparing an inactivated vaccine. In addition, the Acinetobacter lwoffii, tetraodotoxin pseudoalteromonas and pseudomonas are used for preparing a bigeminy or trigeminy inactivated vaccine which is used for immunizing the turbot ascites disease. The preparation process of the inactivated vaccine for the ascites disease is simple, the yield is stable, the cost is low, and a large amount of inactivated vaccines with high immune effect can be obtained. The immune protective rate of the inactivated vaccine prepared by the method can reach 70%. The vaccine is a pure biological agent, has the characteristics of safety and environment friendliness, and dose not causes medicament residues and environment pollution; and by using the method, the generation and popularization of the turbot ascites disease are fundamentally suppressed, and a technical support is provided for preparing the novel inactivated vaccine for the turbot ascites disease.

Description

technical field [0001] The invention belongs to the field of microbial vaccine preparation, and in particular relates to a turbot pathogenic strain and an ascites disease inactivated vaccine. Background technique [0002] Turbot (Scophthalmas maximus) is a rare seawater fish species in Europe. It is native to the United Kingdom and belongs to the flounder family. One of the excellent marine cultured fish. my country has been introduced by the Yellow Sea Fisheries Research Institute for artificial breeding since 1992, and has reached a certain scale. It has gradually become an excellent aquaculture species in northern my country and the main target of factory farming, producing good economic and social benefits. However, with the expansion of the breeding range and the increase of the breeding density, as well as the degeneration of the species, the problem of turbot diseases has become increasingly prominent. Ascites disease is a comprehensive disease with wide prevalence ...

AI Technical Summary

Problems solved by technology

[0003] The treatment of turbot ascites disease currently mainly relies on antibiotics. Although it has a certain effect, it cannot fundamentally control the disease, and the fish body is prone to drug resistance, resulting in drug residues in the body and in the river water environment, destroying the Ecological balance, threatening human health and safety

In addition, fish schools are prone to anorexia symptoms during illness, so the method of feeding bait is not ideal