A kind of preparation method of low-density lipoprotein affinity adsorption hemodialysis membrane material
A low-density lipoprotein and hemodialysis technology, which is applied in the fields of membrane surface engineering and bioseparation engineering, can solve the problems of cumbersome and lengthy treatment process, patient protein loss, and complicated operation, so as to improve hydrophilicity and blood compatibility, Efficient selective separation and low energy consumption
Examples
Embodiment 1
[0021] The polysulfone membrane was soaked and cleaned with acetone to remove impurities adsorbed on the surface of the membrane, and the acetone was removed by vacuum drying. Place the pretreated film sample between the upper and lower plates in the chamber of the plasma processing machine, first pass in argon gas and maintain it for 1 minute, then pass in ammonia gas and keep the composition of the atmosphere in the machine chamber constant, and then turn on the plasma The power supply of the body processor, adjust the voltage to 30 volts, and after the current is stable, carry out the normal-pressure low-temperature plasma treatment for 30 seconds, then turn off the power supply and the gas valve, and take the membrane sample out of the reaction chamber. Rinse three times with acetone, dry in vacuo, and place in a desiccator until ready to use. Immerse the plasma-treated membrane sample in a citric acid buffer solution at pH = 4.0 with a heparin concentration of 0.1 g / L and...
Embodiment 2
[0023] The polysulfone membrane was soaked and cleaned with ethanol to remove impurities adsorbed on the surface of the membrane, and the ethanol was removed by vacuum drying. Place the pretreated film sample between the upper and lower plates in the chamber of the plasma processing machine, first pass in argon gas and maintain it for 3 minutes, then pass in ammonia gas and keep the composition of the atmosphere in the machine chamber constant, and then turn on the plasma The power supply of the body processor, adjust the voltage to 20 volts, and after the current is stable, carry out the normal-pressure low-temperature plasma treatment for 60 seconds, then turn off the power supply and the gas valve, and take the membrane sample out of the reaction chamber. Rinse three times with acetone, dry in vacuo, and place in a desiccator until ready to use. Immerse the plasma-treated membrane sample in a citric acid buffer solution at pH = 4.5 with a heparin concentration of 0.5 g / L an...
Embodiment 3
[0025]The polysulfone membrane was soaked and cleaned with ethanol to remove impurities adsorbed on the surface of the membrane, and the ethanol was removed by vacuum drying. Place the pretreated film sample between the upper and lower plates in the chamber of the plasma processing machine, first pass in helium and maintain it for 5 minutes, then pass in carbon dioxide and keep the composition of the atmosphere in the machine chamber constant, and then turn on the plasma Processor power supply, adjust the voltage to 20 volts, after the current is stable, carry out atmospheric pressure low-temperature plasma treatment for 120 seconds, then turn off the power supply and gas valve, and take the membrane sample out of the reaction chamber. Rinse three times with acetone, dry in vacuo, and place in a desiccator until ready to use. Immerse the plasma-treated membrane sample in a citric acid buffer solution at pH = 5.0 with a heparin concentration of 0.6 g / L and add 1-(3-dimethylamin...
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Abstract
Description
Claims
Application Information
- IPC
- B01D71/06; B01D67/00; B01D69/02; B01J20/26; B01J20/28; B01J20/30; A61M1/18
- Inventors
- 黄小军; 李晶