A drug-coated titanium nail with calcium alginate fiber as carrier

Abstract

The invention belongs to the field of medical devices, and specifically relates to a drug-coated titanium nail with calcium alginate fiber as a carrier. Human implants, artificial organs and catheters can be coated with calcium alginate fibers or coated with calcium alginate fibers as drug-controlled release carriers. The titanium nails are used for open and laparoscopic anastomotic staplers , skin suture, linear stapler, clip applier, titanium nails with a diameter of 0.1-0.5, titanium nails made of TA1, TA2 and metal nails made of 316LVM stainless steel, self-reinforced poly-L-lactide SR-PLLAl2 nails and self-reinforced poly The coating of L-polyglycolide SR-PGA nails can effectively improve the use of surgical stomach, lung and other tissues and digestive tract surgical tissues, reduce the incidence of complications of patients, improve the survival rate and quality of life of patients, and the process is simple. The cost is low, the coating of the titanium nail is uniform, and the loading capacity of the drug and the controlled release carrier is also greatly increased.

Description

Technical field:

[0001] The invention belongs to the field of medical devices, in particular to a drug-coated titanium nail with calcium alginate fiber as a carrier. Background technique:

[0002] Titanium nails are widely used in the field of medical devices, and are often used in surgical stomach, lung and other tissues and digestive tract surgical tissues. However, due to the biological inertia of titanium, when the suture area oozes, inflammation, etc., it will cause suture failure. When the titanium nail and its surrounding tissue heal, the surface properties of the titanium nail play a key role in the tissue. Therefore, many technical methods for the surface modification of the titanium nail have been proposed in the field of medical devices, including improving the physical and chemical properties of the titanium nail surface, surface morphology, and Biochemical properties, etc. Although the current drug coating method is simple in process operation, the coating is pr...