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Iodine-contained cervix antibiosis repair material and preparation method thereof
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A technology for repairing materials and cervix, which can be used in medical science, absorbent pads, bandages, etc., and can solve problems such as affecting curative effect.
Inactive Publication Date: 2012-01-11
甘少磊
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Summary
Abstract
Description
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Problems solved by technology
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Problems solved by technology
Due to drug lavage and local application, it is difficult to keep the drug in the lesion for a long time, which greatly affects the curative effect
Method used
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[0025] Step 2: Add 5g of carboxymethyl chitosan to solution A, stir well until fully dissolved to obtain B;
[0026] Step 3: Add 2g of sodium hyaluronate to solution B, stir well until completely dissolved to obtain mixed solution C;
[0027] Step 4: Add 1g of iodine grains to C, stir well until the mixture is uniform, and obtain D;
[0028] Step 5: Take 3ml of D and pour it into the mold, freeze at -10°C to -5°C for 2 hours, then vacuum freeze-dry at -35°C to -25°C for 6 hours to obtain a dry antibacterial material;
[0029] Step 6: Disinfect the antibacterial material with Co60 to obtain the required iodine-containing cervical antibacterial repair material.
[0030]
Embodiment 2
[0032] Step 1: 4g gelatin is dissolved in the 2wt% acetic acid aqueous solution of 100ml to obtain solution A;
[0033] Step 2: Add 4g of carboxymethyl chitosan to solution A, stir well until fully dissolved to obtain B;
[0034] Step 3: Add 1g of sodium hyaluronate to solution B, stir well until completely dissolved to obtain mixed solution C;
[0035] Step 4: Add 1g of iodine grains to C, stir well until the mixture is uniform, and obtain D;
[0036] Step 5: Take 3ml of D and pour it into the mold, freeze at -10°C to -5°C for 2 hours, then vacuum freeze-dry at -35°C to -25°C for 6 hours to obtain a dry antibacterial material;
[0037] Step 6: Disinfect the antibacterial material with Co60 to obtain the required iodine-containing cervical antibacterial repair material.
Embodiment 3
[0039] Step 1: 4g gelatin is dissolved in the 2wt% acetic acid aqueous solution of 100ml to obtain solution A;
[0040] Step 2: Add 1g of sodium hyaluronate to solution A, stir well until completely dissolved to obtain B;
[0042] Step 4: Add 1g of povidone iodine to C, stir well until the mixture is uniform, and obtain D;
[0043] Step 5: Take 3ml of D and pour it into the mold, freeze at -10°C to -5°C for 2 hours, then vacuum freeze-dry at -35°C to -25°C for 6 hours to obtain a dry antibacterial material;
[0044] Step 6: Disinfect the antibacterial material with Co60 to obtain the required iodine-containing cervical antibacterial repair material.
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Abstract
The invention discloses an iodine-contained cervixantibiosisrepair material and a preparation method thereof. The iodine-contained cervixantibiosisrepair material comprises the following raw material components according to parts by weight: 0.01-100 parts of gelatin, 0.01-100 parts of water-soluble chitosan, 1 part of iodine particles or iodine complex and 0.1-300 parts of acidic aqueous solution. The preparation method comprises the following steps of: adding the gelatin and the water-soluble chitosan into the acidic aqueous solution; fully stirring; adding the iodine particles or iodine complex; injecting into a die; and freezing and drying in vacuum to obtain dry antibiosis material. The preparation method has the characteristics of simple formula, easily-realized preparation technology, low temperature, low vacuum degree, low energy consumption and low pollution and conforms to the requirement of synthetizing material in the mode of soft processing.
Description
technical field [0001] The invention belongs to the technical field of biomedical materials, and in particular relates to a cervical antibacterial repair material with simple preparation, good biocompatibility and remarkable effect and a preparation method thereof. Background technique [0002] Cervicitis is a common disease in women of childbearing age, there are two kinds of acute and chronic. Acute cervicitis often coexists with acute endometritis or acute vaginitis, but chronic cervicitis is more common. The main manifestations are increased leucorrhea, thick mucus or purulent mucus, sometimes accompanied by bloodshot or bloodshot. At present, the treatment methods for cervicitis mainly include methods such as drug lavage and topical application. Due to drug lavage and local application, it is difficult to keep the drug in the lesion for a long time, which greatly affects the curative effect. In addition, cervical surgery (laser, freezing, electrocautery, etc.) will a...
Claims
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Application Information
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