Unlock instant, AI-driven research and patent intelligence for your innovation.

Medicament for treating premature ovarian failure and preparation method thereof

A technology for premature ovarian failure and drugs, which is applied in the directions of drug combinations, pharmaceutical formulations, and medical preparations containing active ingredients, etc., can solve problems such as unsatisfactory clinical effects of traditional Chinese medicines for premature ovarian failure, unreasonable prescription compatibility, and unsatisfactory curative effects.

Active Publication Date: 2014-08-20
深圳市安美信生物医药科技有限公司
View PDF1 Cites 0 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, traditional Chinese medicine has achieved certain curative effect in the treatment of this disease, but the curative effect is not ideal and the effective rate is low. The specific manifestations are: 1. At present, the whole material of traditional Chinese medicine is used as medicine, and the efficacy of the medicine is affected, and the effect is not ideal; 2. The compatibility of prescriptions is not reasonable
It is because of these reasons that the clinical effects of existing Chinese medicines for the treatment of premature ovarian failure are not ideal.

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Medicament for treating premature ovarian failure and preparation method thereof
  • Medicament for treating premature ovarian failure and preparation method thereof
  • Medicament for treating premature ovarian failure and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

preparation example Construction

[0045] The present invention also provides a simple preparation method of the above-mentioned medicine for treating premature ovarian failure, please refer to the technical process for the preparation method of the medicine for treating premature ovarian failure figure 1 . The preparation method of the medicine for treating premature ovarian failure comprises the following steps:

[0046] Step S01. Weighing the components of each Chinese medicine raw material extract:

[0047] According to the formula of the above-mentioned medicine for treating premature ovarian failure, each Chinese medicine raw material extract component is weighed;

[0048] Step S02. Prepare the medicine for treating premature ovarian failure by adopting oral dosage form technology:

[0049] The components of the extracts of Chinese medicinal raw materials in step S01 are mixed, and the medicine for treating premature ovarian failure is prepared by an oral dosage form process.

[0050] Specifically, the...

Embodiment 1

[0063] Pueraria mirifica, yam, soybean germ, angelica, jujube seed are crushed, extracted with ethanol according to the existing process conditions, and then filtered, concentrated, spray-dried, milled, and sieved to obtain Pueraria mirifica extract and Chinese yam respectively. extract, soybean germ extract, angelica extract, jujube seed extract;

[0064] Grape seed and raspberry are pulverized and then extracted with water respectively according to the existing process conditions, and then successively filtered, concentrated, spray-dried, milled, and sieved to obtain grape seed root extract and raspberry extract respectively;

[0065] Weigh 10 grams of kudzu root extract, 10 grams of yam extract, 7 grams of grape seed extract, 6 grams of angelica extract, 5 grams of soybean germ extract, 5 grams of jujube seed extract, 5 grams of raspberry extract, pearl 2 grams of powder, each extract is ground, sieved and mixed, sterilized by 60Co radiation (irradiation dose 6KGY, time irr...

Embodiment 2

[0067] For the extraction methods of Pueraria mirifica extract, yam extract, soybean germ extract, grape seed root extract, angelica extract, jujube seed extract and raspberry extract, refer to the extraction method in Example 1.

[0068] Weigh 9 grams of kudzu root extract, 8 grams of yam extract, 3 grams of grape seed extract, 5 grams of angelica extract, 4 grams of soybean meal extract, 6 grams of jujube seed extract, 4 grams of raspberry extract, pearl Powder 2 grams, each extract is ground, sieved and mixed, sterilized by 60Co radiation (irradiation dose 6KGY, time irradiation 80 minutes), adding 5% of the total weight of the mixture in a sterile environment to a concentration of 70 % ethanol, made into a soft material, passed through a 10-16 mesh sieve to granulate, dried at 70°C for 2 hours in an aseptic environment, and made into traditional Chinese medicine composition granules, granulated according to the existing process in an aseptic environment, and dried in a ster...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention discloses a medicament for treating premature ovarian failure and a preparation method thereof. The medicament for treating premature ovarian failure comprises the following traditional Chinese medicine raw material extracts, by weight: 4-18 parts of a Pueraria extract, 2-20 parts of a yam extract, 2-15 parts of a grape seed extract, 3-20 parts of an angelica extract, 2-10 parts of a soybean extract, 3-15 parts of a spinadateseed extract, 3-13 parts of a raspberry extract and 2-10 parts of a pearl powder. The components in the medicament for treating premature ovarian failure are proportioned according to the principles of warming uterus, nourishing ovary, nourishing yin, tonifying kidney, promoting blood circulation, removing blood stasis, regulating menstruation, arresting leucorrhoea, and inducing diuresis for removing edema, so that the medicament for treating premature ovarian failure has significant clinical effect and high effective rate. In addition, the medicine for treating premature ovarian failure is a safe pure natural herb, and has no toxic or side effect, no damage to liver and kidney function, and no adverse reaction. The medicament for treating premature ovarian failure provided by the invention has a simple preparation method, stable and reliable drug performance, high production efficiency and low production cost.

Description

technical field [0001] The invention belongs to the technical field of pharmaceutical preparations, and in particular relates to a medicine for treating premature ovarian failure and a preparation method thereof. Background technique [0002] Premature ovarian failure refers to women who have established regular menstruation. Before the age of 40, persistent amenorrhea and sexual organ atrophy occur due to ovarian function decline. There is often an increase in gonadotropin levels and a decrease in estrogen. The incidence rate is about 1%~3%, and the incidence rate within 30 years old is about 0.1%. Clinical manifestations are accompanied by pre- and post-menopausal symptoms such as hot flashes, hyperhidrosis, insomnia, irritability, palpitations, fatigue, emotional stress, vaginal dryness, low sexual function, infertility, and early amenorrhea. Congenital aging, if not adjusted and treated in time, can lead to the emergence of chronic diseases such as osteoporosis and card...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/8945A61P15/08A61K35/56A61K35/618
Inventor 王建伟严富国詹泰生李瑛凯恩伯格·柯克克里斯托弗·马斯特森黄昭玲
Owner 深圳市安美信生物医药科技有限公司