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Preparation method of appetite and digestion promoting particles

A technology for appetizing digestion and granulation, applied in the field of medicine, can solve the problems of incompatibility with the modernization requirements of traditional Chinese medicine preparation technology, lack of effective control of extract quality, loss of heat-sensitive components of medicines, etc., to save production time, high yield, The effect of short extraction times

Inactive Publication Date: 2013-03-06
JIANGXI POZIN PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Due to the high decoction temperature and long decoction time, it is time-consuming and labor-intensive, and it is easy to cause damage to the effective components of the medicine, consume energy and easily cause the loss of heat-sensitive components of the medicine, and at the same time, there is no effective control on the quality of the extract. Very incompatible with modern requirements

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0014] Prescription composition: hawthorn 40kg, malt 6kg, Qianqu 6kg, starch 120kg, made into 10000 bags (15g / bag).

[0015] The following steps are used to prepare: Hawthorn, malt and Qianqu three raw materials are ultrasonically extracted twice at room temperature with water as a solvent, each time for 0.5h, and the ultrasonic power is 60kw to obtain a water extract extract, which is filtered through a microporous membrane Filtrate, combine the filtrates, concentrate under reduced pressure at 0.95Mpa at 70°C to a thick paste with a relative density of 1.30 (80°C), add starch, granulate, granulate, and pack in one step.

[0016] Identification: Take 10g of this product, grind it finely, add 20ml of 2% hydrochloric acid ethanol solution, soak for 30 minutes, shake it from time to time, filter, evaporate the filtrate to nearly dryness, add 5ml of ethanol to dissolve, filter, and use the filtrate as the test solution. Take another 3 g of hawthorn reference medicinal material, ...

Embodiment 2

[0018] Prescription composition: Hawthorn 20kg, malt 3kg, Qianqu 3kg, starch 60kg, made into 5000 bags in total (15g / bag).

[0019] The following steps are used to prepare: Hawthorn, malt and Qianqu three-flavor raw materials are ultrasonically extracted twice at room temperature with water as a solvent, each time for 25 minutes, and the ultrasonic power is 45kw to obtain a water extract extract, which is filtered through a microporous membrane Filtrate, combine the filtrates, concentrate under reduced pressure at 0.90Mpa at 60°C to a thick paste with a relative density of 1.28 (70°C), add starch, granulate, granulate, and pack in one step.

Embodiment 3

[0021] Prescription composition: Hawthorn 20kg, malt 3kg, Qianqu 3kg, starch 40kg, sugar powder 18kg, edible sodium bicarbonate 2kg, citric acid 2kg, made 5000 bags of effervescent granules (15g / bag).

[0022] The following steps are used to prepare: Hawthorn, malt and Qianqu three-flavor raw materials are ultrasonically extracted twice at room temperature with water as a solvent, each time for 25 minutes, and the ultrasonic power is 50kw to obtain a water extract extract, which is filtered through a microporous membrane Filtrate, combine the filtrates, concentrate under reduced pressure at 0.90Mpa at 60°C to a thick paste with a relative density of 1.28 (70°C), add various excipients, granulate, granulate, and pack in one step.

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Abstract

A preparation method of appetite and digestion promoting particles belongs to the technical field of medicines. The appetite and digestion promoting particles comprises the following raw medicines by weight parts: 40-400 parts of hawthorns, 6-60 parts of malts and 6-60 parts of Qianqu tablets. The appetite and digestion promoting particles are prepared by adopting the following steps: (1) carrying out supersonic extraction on the hawthorns, the malts and the Qianqu tablets by using water as a solvent to obtain a water extract; (2) filtering a water extract by using microfiltration membranes, and concentrating the water extract till thick paste is obtained; and (3) adding starch into the thick paste and uniformly mixing, pelletizing, drying, arranging particles and conducting subpackaging to obtain the appetite and digestion promoting particles. The preparation method has the beneficial effects that the appetite and digestion promoting particles have the characteristics of short extraction time, high yield and no need of heating through ultrasonic extraction by adopting advanced preparation technologies such as one-step pelletizing by the ultrasonic extraction, the production time is saved, the extraction ratio is increased, the degradation and the loss of effective constituents, particularly temperature-sensitive constituents in medicines are reduced, the extraction technology is simplified, the production cost is reduced, and the quality of products is improved.

Description

technical field [0001] The invention belongs to the technical field of medicine, and in particular relates to a preparation method of Kaiweixiaoshi granules. Background technique [0002] Kaiweixiaoshi granules are composed of three raw materials of hawthorn, malt and Qianqu. Modern studies have shown that hawthorn contains a variety of organic acids such as maslinic acid, which can enhance gastric acid and help food digestion. The lipase contained in hawthorn can also promote the digestion of fatty foods. The effect of astringent and dysentery; malt has the effects of promoting qi and eliminating food, invigorating the spleen and appetizing, reducing breast milk and reducing swelling; Qianqu is prepared by solid-state fermentation of 24 traditional Chinese medicines such as Poria cocos and tangerine peel and distiller's yeast, rich in biologically active blood, and Contains a large amount of probiotics that help digestion, and has special effects such as invigorating the s...

Claims

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Application Information

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IPC IPC(8): A61K36/899A61P1/14
Inventor 肖军平郭峰吴永忠李旭
Owner JIANGXI POZIN PHARMA
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