Kidney bean phytolectin applications in preparation of human drugs and drug composition thereof

A plant lectin and composition technology, which is applied in the directions of pharmaceutical combinations, plant raw materials, plant/algae/fungus/moss components, etc., can solve the problems of inconvenient practical application, short storage time, etc., and achieves long storage time and convenient use. Effect

Active Publication Date: 2013-06-19
YUNNAN KANGZHOU BIOLOGICAL SCI & TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, since the live bacteria need to be stored at low temperature and the storage time is short, it is inconvenient for practical applications, especially for business trips, etc.

Method used

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  • Kidney bean phytolectin applications in preparation of human drugs and drug composition thereof
  • Kidney bean phytolectin applications in preparation of human drugs and drug composition thereof
  • Kidney bean phytolectin applications in preparation of human drugs and drug composition thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0107] Embodiment 1, formula A. In 100 ml of liquid gel contains:

[0108] White Kidney Bean Phytolectin 0.5g,

[0109] Tremella polysaccharide 2.0 grams,

[0110] Oligosaccharides (total amount of stachyose and raffinose) 0.5g

[0111] Bletilla jelly 0.2g

[0112] NaCl 0.85 g,

[0113] pH buffer: acetic acid-sodium acetate buffer solution (pH4.5), take 1.8 grams of sodium acetate, add 0.98 ml of glacial acetic acid, and dilute with water to 100 ml, that is,

[0114] Stabilizer: PEG 4000 2.0 g,

[0115] Preservative: Potassium sorbate 0.3 g,

[0116] The pH is 4.5.

[0117] Add 0.5-2.0ml of gel liquid to 100-200ml of water, which can be used for daily care and cleaning of women's vulva and vagina. After many people have actually used it, 1-2 times a day, it has obvious effects in reducing abnormal leucorrhea, eliminating odor and itching and other adverse symptoms.

Embodiment 2

[0118] Example 2. On the basis of formula A, three needles, extracts of Scutellaria baicalensis or Sophora flavescens were added to form formula B. Formulation B contains in 100ml gel solution:

[0119] Phytohemagglutinin 0.5 g,

[0120] Tremella polysaccharide 2.0 grams,

[0121] Oligosaccharides (total amount of stachyose and raffinose) 0.5g,

[0122] Bletilla striata gum 0.2 g,

[0123] Scutellaria baicalensis dry powder, three needles dry powder and Sophora flavescens dry powder each 1.0 g, a total of 3.0 g of the resulting water extract,

[0124] NaCl 0.85 g,

[0125] pH buffer: citric acid-disodium hydrogen phosphate buffer (pH4.0). Liquid A: Take 21g of citric acid or 19.2g of anhydrous citric acid, add water to dissolve to 1000ml, and store in the refrigerator. Solution B: Take 71.63g of disodium hydrogen phosphate, add water to dissolve it into 1000ml. Take 61.45ml of the above-mentioned solution A and 38.55ml of solution B, mix, shake well,

[0126] Stabilizer...

Embodiment 3

[0129] Embodiment 3, to the treatment of vaginal disease

[0130] According to the A formula of Example 1, when vaginal disease occurs, 2-3ml is injected into the vagina each time. 1-2 times a day. The above is the therapeutic dose. Observe after 48 hours, if then should adopt the formula B of embodiment 2 when not obviously taking a turn for the better. Satisfied with the treatment effect of vaginal diseases.

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Abstract

The invention discloses kidney bean phytolectin applications in preparation of human drugs and a drug composition, and belongs to the technical field of drugs. Kidney bean phytolectins are used as active components for preparing drugs used for adding lactobacillus amounts in woman vaginas. The drug composition adopts the kidney bean phytolectins, tremella polysaccharide, stachyose or / and raffinose and bletilla gum, or added scutellaria, Hollygreen Barberry and matrine extraction as the active components. The drug composition comprises relative weight parts of that 0.5-1.0 part of the kidney bean phytolectins, 1.5-3.0 parts of the tremella polysaccharide, 0.2-2.0 parts of the stachyose or / and raffinose, 0.2-0.5 part of the bletilla gum and 1.0-3.0 parts of the extraction of one kind or more than one kind of scutellaria dry powder, Hollygreen Barberry dry powder and matrine dry powder. The kidney bean phytolectin applications in preparation of people use drugs and the drug composition can be water-soluble complex liquid and is best to be gel, and also can be solid dosage forms such as suppository, disintegrating tablets and the like which are drug dosage forms suitable for external uses. Compared with the prior art, obtained products do not need to be preserved in a low temperature and is long in storage time and convenient to use.

Description

technical field [0001] The invention belongs to the technical field of human medicine. Background technique [0002] The microbiota parasitic in the vagina of healthy women mainly include bacteria, fungi, protozoa and viruses. They mainly inhabit the mucosal folds and fornix of the vagina, followed by the cervix. The main resident bacteria in the vagina are Lactobacillus, Staphylococcus epidermidis, Escherichia coli, Corynebacterium, Group B Streptococcus, Streptococcus faecalis, Mycoplasma, Candida albicans, Peptococcus and Bacteroides and so on. A variety of normal microbial communities in the vagina, hosts, and the environment constitute a dynamic vaginal micro-ecological balance that restricts each other, coordinates with each other. The micro-ecological balance of the vagina plays an important role in maintaining its self-purification function and the health of the host. When the host’s vaginal habitat changes drastically due to the use of broad-spectrum antibiotics,...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K38/16A61K9/06A61P15/02A61K31/715A61K31/702A61K36/898
Inventor 王敏康赵红朱轩轩
Owner YUNNAN KANGZHOU BIOLOGICAL SCI & TECH
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