A kind of glatiramer acetate microsphere and preparation method thereof

A technology of glatiramer acetate and microspheres, which is applied in the direction of pharmaceutical formulas, medical preparations containing active ingredients, peptide/protein components, etc., which can solve frequent problems, achieve stable disease conditions, stable quality, and reduce the frequency of medication.
CN103169670BActive Publication Date: 2016-07-06HYBIO PHARMA
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Patent Information

Authority / Receiving Office
CN Β· China
Patent Type
Patents(China)
Current Assignee / Owner
HYBIO PHARMA
Publication Date
2016-07-06

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Abstract

The invention relates to an acetic acid copaxone microsphere and a preparation method thereof. The preparation method is simple in process, and the encapsulation efficiency of the prepared acetic acid copaxone microsphere is high and stable in quality.
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Description

Technical field

[0001] The invention relates to a medicinal microsphere and a preparation method thereof, in particular to a glatiramer acetate microsphere and a preparation method thereof. Background technique

[0002] Glatirameracetate (abbreviated as GA) is an acetate salt of an artificial peptide, which contains a mixture of four randomly polymerized natural amino acids: L-glutamic acid, L-alanine, L-lysine and L-tyrosine. The average molecular weight of glatiramer acetate is 5,000-9,000 daltons.

[0003] Glatiramer acetate (trade name: ) is developed and manufactured by Israel's Teva Pharmaceutical Industries Ltd. (TEVA). It was approved by the U.S. FDA in 1996 for the treatment of multiple sclerosis. Currently There are two products: water for injection and freeze-dried powder for injection, both for subcutaneous injection.

[0004] In Western countries with more people with multiple sclerosis, The efficacy and tolerability have been fully affirmed. In additio...

Claims

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