Amino arene structure unit-containing polyacrylate functionalized polymer and preparation method thereof

Abstract

The invention relates to an amino arene structure unit-containing polyacrylate functionalized polymer and a preparation method thereof. The preparation method comprises the steps of: by utilizing a method of initiating solution polymerization through free radicals, initiating an amino arene structure unit-containing polyacrylate monomer to be in free radical polymerization in an alcohol-water solvent, performing molecular weight regulation to the polymer by lauryl mercaptan, separating according to different solubilities of polymers with different molecular weights in the alcohol-water system to obtain the amino arene structure unit-containing polyacrylate functionalized polymer with the molecular weight range of 4,000-12,000. The functionalized polymer can be used for entirely replacing o-chloroaniline for preparing vitamin B1, can be recycled after being filtered, the preparation method is simple and convenient to operate, and high in yield, thereby being an industrialized green and environment-friendly production method with the raw material cost advantage.

Description

technical field [0001] The invention relates to a polyacrylate functional polymer containing amino aromatic hydrocarbon structural units and a preparation method thereof, belonging to the technical field of polyacrylate functional polymers. Background technique [0002] As an important basic nutrient, vitamin B1 has many important physiological functions. The structural formula of vitamin B1 is as follows: [0003] [0004] As an important basic nutrient, vitamin B1 has many important physiological functions. In the past ten years, the preparation of vitamin B1 and its derivatives has attracted much attention. Among them, 2-methyl-4-amino-5-aminomethylpyrimidine is the key intermediate commonly used in the preparation of vitamin B1. And the present three kinds of routes about the synthesis of 2-methyl-4-amino-5-aminomethylpyrimidine all have various drawbacks: such as the cyanopyrimidine route needs to use a large amount of ethyl acetimide hydrochloride (1.8 to 2 equiv...

AI Technical Summary

Problems solved by technology

And the present three kinds of routes about the synthesis of 2-methyl-4-amino-5-aminomethylpyrimidine all have various drawbacks: such as the cyanopyrimidine route needs to use a large amount of ethyl acetimide hydrochloride (1.8 to 2 equivalents), the raw material and malononitrile are expensive, which is not conducive to the reduction of product cost; the reaction steps of the formyl pyrimidine route are complicated, the reaction cycle is long, and an autoclave (about 50 kg pressure) is used for hydrogenation reaction, which is difficult to implement industrially ; and the formylaminopyrimidine route takes 3-aminopropionitrile as starting raw material, although the raw material of this route is cheap and easy to get, the reaction conditions of each step are relatively mild, and the yield is higher, which is conducive to product cost control

But this route has fatal disadvantages: it uses highly carcinogenic o-chloroaniline, which requires high operating environment and is not conducive to environmental protection; and despite steam distillation and multiple recrystallizations, it is still difficult to remove trace amounts of o-chloroaniline in the final product vitamin B1. Chloroaniline

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