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[0003] At present, most of the commonly used drugs for bacterial infectious diseases are antibiotics and broad-spectrum antibacterial drugs, such as imipenem, secondly citioperazone-sulbactam, vancomycin, and secondly nitrofurantoin, which have large side effects and will cause Develop drug resistance, leading to superbugs
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Embodiment 1
[0036] Embodiment 1 Antibacterial activity research of patchouli ketone
[0037] 1 Materials and Instruments
[0038] 1.1 Experimental Instruments
[0039] Multi-point inoculation instrument (Japan Sakuma Manufacturing Co., Ltd., SAKUMAMIT-P type), electric heating constant temperature water bath (Beijing Tonghua Medical Instrument Factory, DSY-1-6 holes), laboratory autoclave (SANYO, MLS-3780 type), CO 2 INCUBATOR (SANYO, MOC-15A), energy-saving purification workbench (Chengdu Xinguang Feilante Purification Engineering Co., Ltd.).
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Abstract
The invention relates to the uses of pogostone (patchoulenone) and its derivatives in the preparation of antibacterial drugs, healthcare food, food, cosmetics, disinfectors or daily chemical articles. The invention also provides a type of antibacterial drug, healthcare food, food, cosmetics, disinfector or daily chemical article. Pogostone has good inhibitory effects on pathogenic bacteria (such as Staphylococcus, etc) or conditional pathogenic bacteria and can be effectively used for treatment of bacterial infectious diseases. Meanwhile, pogostone can also be active against methicillin-resistant bacteria, and thus can be developed as an potential antibacterial agent for clinical therapy.
Description
technical field [0001] The present invention relates to the new application of patchoulone and its derivatives, specifically, the application in the preparation of medicines for treating bacterial infectious diseases. Background technique [0002] Bacterial infectious diseases refer to diseases caused by bacterial infections. Among the common clinical pathogenic bacteria, there are many Gram-negative bacteria, such as Escherichia, Enterobacter, and Pseudomonas bacteria, and there are also Gram-positive bacteria, such as Staphylococcus and Enterobacteriaceae. Bacteria of the genus Coccus. [0003] At present, most of the commonly used drugs for bacterial infectious diseases are antibiotics and broad-spectrum antibacterial drugs, such as imipenem, secondly citioperazone-sulbactam, vancomycin, and secondly nitrofurantoin, which have large side effects and will cause Drug resistance, leading to the emergence of superbugs. Methicillin-resistant Staphylococcus aureus is a kind ...
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