Puerarin sodium phosphate injection and preparation method thereof

A technology of sodium puerarin phosphate and puerarin phosphate, which is applied in the field of injections whose main drug is sodium puerarin phosphate and its preparation, and can solve problems such as instability of puerarin injection
CN103784397AActive Publication Date: 2014-05-14SHENZHEN XINGYIN PHARML
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
SHENZHEN XINGYIN PHARML
Publication Date
2014-05-14

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Abstract

The invention relates to a puerarin sodium phosphate injection and a preparation method thereof. The puerarin sodium phosphate injection comprises puerarin sodium phosphate, a preservative, an isoosmotic adjusting agent, a pH value adjusting agent, an antioxygen, a local analgetic and injection water, wherein due to the addition of the antioxygen, the stability of the puerarin sodium phosphate injection can be improved, and due to the addition of the local analgetic, the pain of a patient can be lightened and no influence is caused to a main drug. The preparation method of the puerarin sodium phosphate injection mainly comprises the steps: weighing, dissolving, adsorbing a heat source by active carbon, filtering, metering volume, end-filtering, sub-packaging, plugging and covering. The puerarin sodium phosphate injection is used for adjuvant therapy of the coronary heart disease, the stenocardia, the myocardial infarction, the retina artery and vein occlusion, sudden deafness, ischemic cerebrovascular disease and the like. The puerarin sodium phosphate injection is stable in quality, accurate in treatment effect, and beneficial to acceptation by a patient.
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Description

technical field

[0001] The invention relates to the field of preparations, in particular to an injection whose main drug is puerarin sodium phosphate and a preparation method thereof. Another authorized invention patent of our company, CN10171267.6, has disclosed the structure and preparation method of puerarin sodium phosphate. Background technique

[0002] Puerarin is the main active ingredient in the traditional Chinese medicine puerarin, a flavonoid glycoside, chemically named 7,4'-dihydroxy-8-β-D-glucose isoflavone, and the molecular formula is C 21 h 20 o 9 , molecular weight 416.38, CAS number 82373-94-3. Puerarin has the functions of improving immunity, enhancing myocardial contractility, protecting myocardial cells, lowering blood pressure, and anti-platelet aggregation. It is widely used in the treatment of clinical hypertension, coronary heart disease, acute cerebral infarction, diabetes and other diseases.

[0003] However, the water solubility of puerarin i...

Claims

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