Surface enhanced Raman scattering microfluidic system based on PDMS three-dimensional micro-nano antenna

Abstract

The invention provides a surface enhanced Raman scattering microfluidic system based on PDMS three-dimensional micro-nano antenna, which is used for molecular detection. A PDMS micro-nano antenna structure is adopted as a silver nanoparticle carrier, a layer of graphene covers the silver nanoparticle carrier so as to form a PDMS/silver nanoparticle/graphene-based Raman scattering base with the three-dimensional micro-nano antenna structure, which is taken as a detection area; a laser light source and a spectrograph are connected with an optical fiber and an SERS (Surface-Enhanced Raman Scattering) probe, and irradiate the detection area of a microchannel; the microchannel adopts PDMS materials. According to the system, graphene protects the oxidization of silver nanoparticles on one hand, and brings high chemical reinforcement on the other hand; the PDMS three-dimensional micro-nano antenna structure has a large specific surface area and more Raman enhanced hot points, effectively reinforces the filling effect of the silver nanoparticles, and is beneficial to localized surface plasmon resonance, and the strength of Raman scattering signals is enhanced; according to the system, the PDMS materials and the optical fiber are coupled, the manufacturing process is simple, the cost is low, and portable and on-line detection of molecules can be realized conveniently.

Description

technical field [0001] The invention belongs to the fields of nanophotonics and microfluidics, and specifically relates to surface-enhanced Raman scattering spectroscopy technology. Background technique [0002] With the development of human society, the demand for trace molecular detection of human health diseases, food pollution, environmental toxins, drugs, and national security explosives such as military defense is increasing, and it has become a rapid growth in the fields of chemistry, physics, life sciences and nanotechnology. research topics. Spectral wavelengths, intensities, and polarization states of molecules absorbed or emitted under different conditions are inherently related to the structural characteristics of the molecules. Therefore, spectroscopic methods are considered to be powerful tools for detecting and studying trace molecules. Among them, Raman spectroscopy is an inelastic collision of a photon incident on a molecule, and its frequency change corres...

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Problems solved by technology

[0004] In order to solve the shortcoming that silver nanoparticles are easily oxidized by air, the present invention proposes the use of graphene, on the one hand to protect the easily oxidized silver nanoparticles, on the one hand to obtain good chemical enhancement; at the same time, in order to solve the problem that the SERS detection system has a large volume ...

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