Multiple composition for oral treatment

A technology for treating compositions and oral cavity, applied in medical science, dentistry, dental preparations, etc., can solve the problems of weak alkaline antibacterial performance, inability to take into account short-term and long-term synergy, and achieve the effect of reducing sensitivity

Active Publication Date: 2015-04-08
DONGGUAN HONGYUAN MEDICINE TECH +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] Throughout the clinical application in recent years, although a large number of special desensitizing toothpastes have had a positive effect on desensitization, none of them can solve clinical oral problems involving multiple dental lesions, and patients with dentin sensitivity are accompanied by caries, gingival bleeding and adverse Dental plaque problems caused by habits, based on the co

Method used

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  • Multiple composition for oral treatment

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0050] Prepare a desensitizing toothpaste containing two components of bioglass-potassium dihydrogen phosphate. The thickness of the mesoporous structure layer of the bioglass surface layer is one-fifth of the particle radius. The components (mass percentage, %) of the toothpaste are listed as follows:

[0051] 15 % biological glass particles

[0052] 2% potassium dihydrogen phosphate

[0053] 30% friction agent - silica ball particles

[0054] 3% Thickener—Carboxymethyl Cellulose

[0055] 20% Humectant—Polyethylene Glycol

[0056] 2% Blowing Agent—Sodium Lauryl Sulfate

[0057] 0.3% flavor enhancer - peppermint flavor

[0058] 0.1% Preservative - Potassium Sorbate

[0059] The rest is water;

[0060] Wherein, the mass percentage of each component in the bioglass is:

[0061] CaO 28%

[0062] SiO 2 38%

[0063] P 2 o 5 2%

[0064] B 2 o 3 12%

[0065] CuO 0.5%

[0066] ZnO 0.3%

[0067] K 2 O 16%

[0068] Na 2 O 3.2%;

[0069] Among them, the particle ...

Embodiment 2

[0076] Prepare desensitizing chewing gum containing two components of bioglass-potassium hydrogen phosphate, the thickness of the mesoporous structure layer on the surface layer of bioglass is a quarter of the particle radius, and the components (mass percentage, %) of the chewing gum are listed as follows:

[0077] 20% bioglass granules

[0078] 2.5% potassium phosphate

[0079] 15% friction agent - silicon oxide particles

[0080] 8% Thickener—Carboxymethyl Cellulose

[0081] 5% Humectant—Polyethylene Glycol

[0082] 1% blowing agent - sodium lauryl sulfate

[0083] 1% flavor enhancer - glucose

[0084] 0.1% Preservative - Potassium Sorbate

[0085] 25% Gum Base - Styrene Butadiene Rubber

[0086] 3% softener - beeswax

[0087] The rest is water;

[0088] Wherein, the mass percentage of each component in the bioglass is:

[0089] CaO 26%

[0090] SiO 2 40%

[0091] P 2 o 5 2%

[0092] B 2 o 3 16%

[0093] CuO 0.4%

[0094] ZnO 0.4%

[0095] K 2 O 12.2...

Embodiment 3

[0103]Prepare a desensitizing dental adhesive containing two components of bioglass-potassium phosphate, the thickness of the mesoporous structure layer of the surface layer of bioglass is a quarter of the particle radius, and the components (mass percentage, %) of the composition are listed as follows :

[0104] 25% biological glass particles

[0105] 2% potassium dihydrogen phosphate

[0106] 10% friction agent - silica ball particles

[0107] 5% Thickener—Carboxymethyl Cellulose

[0108] 18% Humectant - Polyethylene Glycol

[0109] 0.5% blowing agent - sodium lauryl sulfate

[0110] 0.5% flavor enhancer - peppermint flavor

[0111] 0.1% Preservative - Potassium Sorbate

[0112] The rest is water;

[0113] Wherein, the mass percent composition of each component in the bioglass is:

[0114] CaO 30%

[0115] SiO 2 36%

[0116] P 2 o 5 4%

[0117] B 2 o 3 16%

[0118] CuO 0.2%

[0119] ZnO 0.6%

[0120] K 2 O 10%

[0121] Na 2 O 3.2%;

[0122] Among th...

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Abstract

The invention discloses a multiple composition for oral treatment. The multiple composition comprises 2-25 parts of bioglass and 0.1-10 parts of phosphate of potassium. The bioglass is spherical or ellipsoidal and the granularity is 220-2500 nanometers; the surface layer of bioglass is a mesoporous structure, wherein the mesoporous bore diameter is 6-45 nanometer; the bioglass comprises the components in form of oxides in parts by weight: 20-35 parts of CaO, 30-38 of SiO2, 0.1-1.8 parts of P2O5, 12-18 parts of B2O3, 0.1-0.8 part of CuO, 0-0.7 part of ZnO and 0-4 parts of Na2O, wherein the sum of CuO and ZnO accounts for 0.6-1.5% of the total weight and the ratio of the content of K2O and the sum of CuO and ZnO is (8-30): 1. The composition can be used for immediately reducing sensation, desensitizing with long action, protecting gum and stopping bleeding, inhibiting antibacterial activity of decayed teeth and whitening the teeth and has extreme promotional and practical values.

Description

technical field [0001] The invention belongs to the field of oral care materials, and in particular relates to a multi-oral oral treatment composition. Background technique [0002] Tooth sensitivity, referred to as tooth sensitivity, refers to the short-term and sharp pain sensation that occurs when the exposed dentin after gum recession encounters stimuli such as acid, sweet, cold, or heat. Tooth sensitivity is usually not diagnosed as a tooth defect and disease. The pain it produces is inconvenient to the patient, and may cause chronic or emotional stress, and even changes in eating habits, refusing cold, hot, sour, sweet and other irritating foods. However, those with tooth sensitivity are often accompanied by some chronic dental or oral lesions, such as frequent gingival bleeding caused by dental caries and gingival degeneration. [0003] The main theories about tooth sensitivity include the theory of odontoblast receptors, the theory of direct stimulation of nerve end...

Claims

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Application Information

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IPC IPC(8): A61K6/033A61K6/838
Inventor 李祥永苟中入彭连生杨贤燕
Owner DONGGUAN HONGYUAN MEDICINE TECH
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