Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Nano calcium silicate-polyetheretherketone (PEEK) composite material and preparation method thereof

A nano-calcium silicate and polyetheretherketone technology, which is applied in medical science, prosthesis, etc., can solve the problems of unsatisfactory mechanical strength, affecting polymer properties, and inability to host osseointegration. Biologically active, integrative-friendly effects

Active Publication Date: 2015-06-24
SHANGHAI NINTH PEOPLES HOSPITAL AFFILIATED TO SHANGHAI JIAO TONG UNIV SCHOOL OF MEDICINE
View PDF1 Cites 12 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, polymer materials also have obvious shortcomings: most of them are not ideal in mechanical strength when used alone; some polymers (such as PMMA) cannot be absorbed by themselves when used as bone fillers; the sterilization process may also affect some properties of some polymers
However, PEEK has a fatal shortcoming—biological inertia, which means that PEEK cannot be well integrated with the host bone after implantation, which greatly limits its wide clinical application.

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Nano calcium silicate-polyetheretherketone (PEEK) composite material and preparation method thereof
  • Nano calcium silicate-polyetheretherketone (PEEK) composite material and preparation method thereof
  • Nano calcium silicate-polyetheretherketone (PEEK) composite material and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0029] (1) Materials and equipment required for the experiment

[0030] Material: PEEK powder (average particle size of 20μm, purchased from the UK Company); Ultra-high molecular weight polyethylene (UHMWPE) plates (molecular weight 2,000,000, purchased from Roechling Engineering Plastics, Germany); cell culture plates (Costar, Corning, USA); MC3T3-E1 cells (for this laboratory liquid nitrogen tank Stored cells); other reagents are commercially available analytical reagents.

[0031] Instruments: Ultra-clean workbench (BIO-HAZARD, VCM-420, Taiwan), electronic analytical balance (METTLERTOLEDO, AB204-E, Switzerland), electromagnetic stirrer (STUART, SM24, UK), high-speed ball mill (QM-3B, Nanjing T-BotaScietechInstruments&Equipment Ltd., China), injection molding machine (BA-300 / 050CD, Battenfeld, Belgium), scanning electron microscope (S-4800, Hitachi, Japan), energy dispersive spectrometer (X-Max, Horiba, Japan), Shape analyzer (JC-2000D3, ShanghaiZhongchengDigitalTechnologyCo.,...

Embodiment 2

[0052] The difference between this embodiment and Embodiment 1 is that in the preparation process of the nm-CS / PEEK composite material provided in this embodiment, the volume ratio of nano calcium silicate powder and PEEK powder is 15:85.

Embodiment 3

[0054] The difference between this embodiment and Embodiment 1 is that in the preparation process of the nm-CS / PEEK composite material provided in this embodiment, the volume ratio of nano calcium silicate powder and PEEK powder is 25:75.

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention provides a nano calcium silicate-polyetheretherketone (PEEK) composite material which is composed of nano calcium silicate and PEEK in a volume ratio of (10-30):(70-90). The nano calcium silicate-PEEK composite material maintains the excellent biomechanical characteristics of the PEEK, and greatly enhances the biological activity of the PEEK. After being implanted into the body, the nano calcium silicate-PEEK composite material can be matched with peripheral normal bones in the mechanical aspect, can be well integrated with the host bone, promotes the adhesion, proliferation and osteogenesis differentiation of the bone source cells, can keep long-term stability, can be used in clinic as a spine interbody fusion device material and a joint prosthesis material, has active practical meanings, and can generate huge social and economic benefits.

Description

Technical field [0001] The invention relates to a polymer composite material, in particular to a nano calcium silicate-polyetheretherketone composite material and a preparation method thereof. Background technique [0002] In orthopedics, plastic surgery, oral and maxillofacial surgery and other fields, implants are the main means to repair and reconstruct damaged bone and joint structure and function. Currently commonly used implant materials in clinical practice include: metals, inorganic non-metals, polymers and composite materials. Metals (such as stainless steel, titanium and titanium alloys, cobalt-chromium-molybdenum alloys) have the advantages of high strength, friction resistance, and non-toxicity, and have been widely used in clinical practice. However, the strength and elastic modulus of metal materials are much higher than that of normal human bone tissue. After implantation in the body, the surrounding bone will be absorbed due to the stress shielding effect, which ...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
IPC IPC(8): C08L61/16C08K3/34A61L27/44
Inventor 汤亭亭马瑞魏杰邬迎阳
Owner SHANGHAI NINTH PEOPLES HOSPITAL AFFILIATED TO SHANGHAI JIAO TONG UNIV SCHOOL OF MEDICINE
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com