Nitrogen-doped carbon quantum dot with high fluorescence quantum yield and preparation method and application of nitrogen-doped carbon quantum dot

Abstract

The invention discloses a nitrogen-doped carbon quantum dot with high fluorescence quantum yield and a preparation method and an application of the nitrogen-doped carbon quantum dot. The carbon quantum dot is obtained by the following steps: mixing a nitrogen-containing carbon source, a surface-modified molecule and high-boiling point alcohol, and fully reacting in an inert protective atmosphere at 200-240 DEG C. The prepared carbon quantum dot has the characteristics of uniform particle size (mainly distributed at 2-4nm), high nitrogen content (can be up to 10wt%), high fluorescence quantum efficiency (can be up to 20%), low cytotoxicity and the like, and can be widely applied to the fields such as cell imaging and living imaging; synthesis and surface modification are finished in one step; and the nitrogen-doped carbon quantum dot is simple in process and low in cost, can be produced in a macro scale, and can fully meet the requirements of industrialized application.

Description

Technical field [0001] The present invention involves a quantum dot material, especially a nitrogen doped carbon quantum dot and its preparation process and application with a high fluorescent quantum yield. It belongs to the field of inorganic non -metal nanomaterials. Background technique [0002] Carbon quantum dots (as follows as "carbon dots") Since being discovered for the first time in 2004, it has attracted widespread attention from scientists due to its superior performance.Compared with traditional semiconductor quantum dots, carbon dots have the following superior properties: good biocompatibility, stable optical luminous performance, wide stimulation wavelength range, the characteristics of the launch wavelength dependency of the excitation wavelength, and the surface is easy to modify.Therefore, carbon points are expected to replace semiconductor quantum dots in the fields of biomarkers, biological images, photoelectric devices, and biosensors. [0003] At present, t...

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Problems solved by technology

However, the above synthesis methods have disadvantages. The electrochemical synthesis method and the microwave method need to use special experimental equipment, and the experimental operation is complicated; the combustion pyrolysis method has a low yield and cannot be prepared in large quantities; the hydrothermal method requires high temperature and high pressure conditions, and the operation is safe. Hidden danger: the acid oxidation method cannot control the uniformity of the product size, and will produce a large amount of harmful gases at the same time

[0004] In short, the synthesis of carbon dots is still in its infancy, and most of the synthesis methods have defects such as multi-step operations, complicated procedures, and low fluorescence quantum efficiency.

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