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Butyrate, butyrate derivative and benzoic acid compound formula, preparation method and application of butyrate, butyrate derivative and benzoic acid compound product as feed additive

A technology of butyrate and benzoic acid, applied in animal feed, animal feed, applications, etc., can solve the problems of not being able to form enough butyric acid molecules, lack of hydrogen ions in the hindgut, and affecting the balance of the gastrointestinal tract

Pending Publication Date: 2015-11-25
SINGAO
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] The existing technology is to add sodium butyrate alone in the feed, and make it enter the intestinal tract through coating technology to have an effect, but there is a lack of hydrogen ions in the hindgut, and it is impossible to form enough butyric acid molecules, but it cannot be added too much. Too much sodium butyrate, because adding too much sodium butyrate will also affect the balance of the gastrointestinal tract

Method used

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  • Butyrate, butyrate derivative and benzoic acid compound formula, preparation method and application of butyrate, butyrate derivative and benzoic acid compound product as feed additive
  • Butyrate, butyrate derivative and benzoic acid compound formula, preparation method and application of butyrate, butyrate derivative and benzoic acid compound product as feed additive
  • Butyrate, butyrate derivative and benzoic acid compound formula, preparation method and application of butyrate, butyrate derivative and benzoic acid compound product as feed additive

Examples

Experimental program
Comparison scheme
Effect test

Embodiment example 1

[0036] Seventy-two 28-day-old healthy weaned piglets were randomly divided into two experimental groups, A and B. Group A was the experimental group, and group B was the control group, with 36 weaned piglets in each group. The test group was fed with 3 kilograms of feed added per ton of the product made according to formula 1 (the content of sodium butyrate was 50%, the content of sodium benzoate was 50%, and the content of dextrin was 0%.) The control group was fed with the product added per ton of feed. 60ppm salinomycin diet. The effect on the digestibility of nutrients in weaned piglets was obtained, and the results are as follows:

[0037] project

[0038] The results show that: 1, formula 1 product improves the nutrient substance digestibility of weaned piglets, wherein the energy digestibility improves by 2.96%, the dry matter digestibility improves by 1.12%, the crude protein digestibility improves by 1.18%, and the phosphorus digestibility improves by 2.58%...

Embodiment example 2

[0040] 20,000 1-day-old AA broilers were selected and randomly divided into two treatment groups, each with 10,000 broilers. The chicks in the test group were fed with 1.5 kg per ton of feed at the stage of feeding according to Formula 2 (the content of sodium butyrate was 20%, the content of sodium benzoate was 70%, and the content of dextrin was 10%.) Add 0.9 kg of the product made according to formula 2 per ton of feed, and the feces will be formed and recovered after 7 days, indicating that the digestion and absorption of broilers is good. In the control group, the feces were thin and soft, and the ammonia smell in the chicken house was heavy, indicating that the digestion and absorption of broilers was not complete.

Embodiment example 3

[0042] Ten 28-day-old piglets with a weaning weight of 4.24 kg were randomly divided into two experimental groups, A and B. Group A was the experimental group, and group B was the control group, with 5 weaned piglets in each group. The test group was fed with 2 kg per ton of feed added according to formula 3 (the content of sodium butyrate was 5%, the content of sodium benzoate was 95%, and the content of dextrin was 0%.) The control group was fed with basic diet. The effect on growth performance of weaned piglets was obtained after 42 days and the results are as follows:

[0043]

[0044] The results showed that the formula 3 product could improve the growth performance of piglets with low weaning weight, the weight gain was increased by 9.4%, the average daily gain (ADG) was increased by 10.66%, and the feed-to-feed ratio (FCR) was improved by 12.16%.

[0045] In this case, butyric acid and benzoic acid are reacted with basic metal ions (such as sodium, potassium, calcium...

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Abstract

The invention discloses a butyrate, butyrate derivative and benzoic acid compound formula, a preparation method and an application of the butyrate, butyrate derivative and benzoic acid compound product as a feed additive. The weight ratio of butyrate or a butyrate derivative and benzoic acid or benzoate is 5%-50% and 50%-95%. With the adoption of the scheme, benzoate and butyrate enter an animal body and are dissociated into acidic molecules, butyric acid stimulates growth of parietal cells, parietal cells produce hydrochloric acid reducing pH value in the stomach, benzoic acid in the stomach inhibits facultative anaerobes such as lactobacillus and anaerobes producing butyric acid, and the two groups of bacterial communities become dominant bacterial communities, generate more endogenous organic acid such as lactic acid and butyric acid and are beneficial to gastrointestinal tract health and animal growth, so that the superimposed effect of benefits of the two components is realized.

Description

technical field [0001] The invention relates to the field of feed additives, in particular to feed additives for regulating animal gastrointestinal microbial flora. Background technique [0002] Sodium butyrate (or butyrate and other butyric acid derivatives) can provide a fast and easily absorbed energy source for the animal body and its tissue cells, and its active ingredient is a short-chain volatile fatty acid - butyric acid, butyric acid Molecules enter the small intestine from the stomach to work, especially the energy preferred by enterocytes (cecum and colon cells), and are the main energy source for colonic mucosal epithelial cells, accounting for about 70% of the energy produced by SCFA oxygen consumption, and are easily transported from the intestine Intraluminal absorption, butyrate undergoes energy metabolism in enterocytes through β-oxidation in the hydroxymethylglutaryl-CoA cycle, first by converting butyrate to butyrate-CoA by butyrate-CoA synthetase, and the...

Claims

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Application Information

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IPC IPC(8): A23K1/16
Inventor 赖州文章亮
Owner SINGAO
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