Method for preparing lipidosome

Abstract

The invention provides lipidosome. The lipidosome is prepared from the following components in percentage by weight: 1-20 percent of lecithin, 1-15 percent of polyol, 0.1-2 percent of a surfactant, 0.01-0.2 percent of inorganic salt and the balance of water. The invention further provides a method for preparing the lipidosome. The method comprises the following steps: firstly, dissolving lecithin in polyol to obtain a uniform organic phase; secondly, uniformly dispersing and dissolving the surfactant and the inorganic salt in water to obtain a uniform aqueous-phase component; thirdly, slowly adding the organic phase into the aqueous phase at a uniform stirring velocity of 300-800rpm to obtain a uniform lipidosome suspension; and finally, performing ultrasonic treatment on the lipidosome suspension for 1-8 minutes with an ultrasonic power of 20-40 percent, stirring until the system is uniform, and naturally cooling the system to room temperature to obtain the lipidosome. The lipidosome prepared by the method has a stable system, can be used for simultaneously covering multiple effective ingredients, is mild to skin, and is a dispersion system with functionality and beautifying property.

Description

technical field [0001] The invention belongs to the technical field of cosmetics and relates to a preparation method of liposomes. Background technique [0002] Liposomes are hollow vesicles formed by phospholipids dispersed in water. They are widely used in cosmetics because of their unique phospholipid bilayers, which have a structure similar to cell membranes and have affinity with the skin. Liposomes provide remarkable properties for cosmetic formulations. They make the skin smooth, soft, elastic, and occlusive, and can create a thin film on the skin to prevent water loss from the skin. In addition, as a coating carrier, liposome can coat fat-soluble and water-soluble active ingredients in its phospholipid bilayer and hollow core, and act on the deep layer of the skin to play a slow-release effect. [0003] In the past ten years, the research on liposome in dermatology and cosmetics is booming. Liposome-containing cosmetics have incomparable advantages of traditional co...

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Problems solved by technology

[0005] For the above-mentioned mechanical problems in the prior art, the invention provides a kind of preparation method of liposome, the preparation method of described this kind of liposome has solved the liposome preparation method in the prior art due to extensive use toxic Organic reagents are likely to cause residues of organic substances and technical problems that are likely to cause damage to the skin

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