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Pharmaceutical composition for treating female climacteric syndrome and preparing method thereof

A composition and syndrome technology, applied in the field of pharmaceutical compositions for treating female climacteric syndrome and the field of preparation thereof, can solve the problems of complex raw materials, high cost, and ineffective effects of traditional Chinese medicine compositions, and achieve better drug treatment effects , low cost, and the effect of solving the root cause of the disease

Inactive Publication Date: 2016-02-03
叶宗耀
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] Chinese patent 201210482089.0 discloses a traditional Chinese medicine composition for treating menopausal syndrome. The traditional Chinese medicine composition is prepared from the following raw materials in parts by weight: 5-20 parts of Epimedium, 3-10 parts of Curculigo, 5- 15 parts, Cistanche 10-30 parts, Phellodendron 10-30 parts, Anemarrhena 10-30 parts, Angelica 5-25 parts, Ligustrum lucidum 5-25 parts, Eclipta 5-15 parts, floating wheat 10-40 parts , Schisandra 5-25 parts, Ophiopogon japonicus 10-30 parts, Scrophulariaceae 10-30 parts, Moutan bark 5-25 parts, Zhuru 5-20 parts, Achyranthes bidentata 5-20 parts, Lily 10-30 parts, raw land 10-30 servings, 5-20 servings of fried jujube kernels, 5-25 servings of Bai Wei, 10-30 servings of Nocturna vine, 5-20 servings of Baiziren, 5-25 servings of motherwort, 10-30 servings of cornus, Poria cocos 5-25 parts, 5-25 parts of polygala and 5-15 parts of licorice. The raw materials of the composition are complicated and the cost is high

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0046] The pharmaceutical composition of Example 1 of the present invention is prepared from the following raw materials in parts by weight: 12 parts of Vitex Vitex, 8 parts of Astragalus, 4 parts of Ginseng, 6 parts of Artemisia argyi, 4 parts of Corydalis Corydalis, 6 parts of Angelica, 4 parts of Toosendan, 5 parts of paeonol bark, 10 parts of malt, 6 parts of mulberry, 5 parts of cinnamon, 4 parts of green skin, 6 parts of white peony root, 4 parts of curcuma, 10 parts of oyster, 4 parts of dried ginger, 10 parts of Poria cocos, 5 parts of Polygonum multiflorum, 5 parts of mussels 6 parts, 6 parts of lily and 8 parts of licorice.

[0047] The preparation method is as follows:

[0048] Step 1: Take Vitex Vitex and pulverize it, place it in a supercritical carbon dioxide extraction device, add 30% ethanol with a volume fraction of 60% of the total volume of Vitex Vitex, control the flow of carbon dioxide to 15L / h, extract pressure to 15MPa, and extract to temperature 40°C, ...

Embodiment 2

[0052] The pharmaceutical composition of Example 2 of the present invention is prepared from the following raw materials in parts by weight: 18 parts of Vitex vitex, 16 parts of astragalus, 10 parts of ginseng, 25 parts of Artemisia argyi, 8 parts of Corydalis, 12 parts of angelica, 8 parts of Toosendan, 14 parts of paeonol, 14 parts of malt, 1 part of mulberry, 8 parts of cinnamon, 8 parts of green skin, 16 parts of white peony root, 8 parts of curcuma, 16 parts of oyster, 12 parts of dried ginger, 15 parts of Poria cocos, 13 parts of Polygonum multiflorum, 13 parts of mussels 14 parts, 14 parts of lily and 18 parts of licorice.

[0053] The preparation method is as follows:

[0054] Step 1: Get Vitex Vitex and pulverize it, place it in a supercritical carbon dioxide extraction device, add 40% ethanol with a volume fraction of 75% of the total volume of Vitex Vitex, control the flow of carbon dioxide to 18L / h, extract pressure to 18MPa, and extract to temperature 50°C, the e...

Embodiment 3

[0058] The pharmaceutical composition of Example 3 of the present invention is prepared from the following raw materials in parts by weight: 16 parts of Vitex vitex, 12 parts of astragalus, 6 parts of ginseng, 18 parts of Artemisia argyi, 6 parts of Corydalis, 10 parts of angelica, 6 parts of Toosendan, 11 parts of paeonol, 13 parts of malt, 7 parts of mulberries, 6 parts of cinnamon, 5 parts of green skin, 12 parts of white peony, 6 parts of curcuma, 14 parts of oysters, 8 parts of dried ginger, 12 parts of poria cocos, 8 parts of Polygonum multiflorum, 7 parts of mussels 10 parts, 10 parts of lily and 12 parts of licorice.

[0059] The preparation method is as follows:

[0060] Step 1: Take Vitex Vitex and pulverize it, place it in a supercritical carbon dioxide extraction device, add 45% ethanol whose volume fraction is 85% of the total volume of Vitex Vitex coarse powder, control the flow rate of carbon dioxide to 20L / h, the extraction pressure to 20MPa, and the extraction...

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PUM

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Abstract

The invention belongs to the field of traditional Chinese medicine, and relates to a pharmaceutical composition for treating female climacteric syndrome and a preparing method thereof. The pharmaceutical composition is prepared from, by weight, 12-18 parts of vitex, 8-16 parts of astragalus membranaceus, 4-10 parts of ginseng, 6-25 parts of folium artemisiae argyi, 4-8 parts of corydalis tuber, 6-12 parts of angelica sinensis, 4-8 parts of szechwan Chinaberry fruit, 5-14 parts of cortex moutan, 10-14 parts of malt, 6-11 parts of mulberry, 5-8 parts of cinnamon, 4-8 parts of pericarpium citri reticulatae viride, 6-16 parts of radix paeoniae alba, 4-8 parts of curcuma zedoary, 10-16 parts of oyster, 4-12 parts of dried ginger, 10-15 parts of poria cocos, 5-13 parts of polygonum multiflorum, 5-13 parts of mussel, 6-14 parts of lily and 8-18 parts of liquorice. The pharmaceutical composition can invigorate vital energy and promote blood flow, regulate menstruation and relieve pain, moisturize dryness by nourishing yin, ease mental anxiety and tonify spleen and kidney and has the advantages of being good in curative effect, mild in side effect, convenient to take, capable of coordinating intestines and stomach and the like.

Description

technical field [0001] The invention belongs to the field of traditional Chinese medicines, and in particular relates to a pharmaceutical composition for treating climacteric syndrome in women and a preparation method thereof. Background technique [0002] Menopausal syndrome is a transitional period in which women's ovarian function gradually declines to disappear completely. A series of clinical symptoms appear due to physiological and psychological changes. Common symptoms include hot sweating, irritability, palpitations, insomnia, depression and forgetfulness. Traditional Chinese medicine refers to menopausal syndrome as "all symptoms before and after menstruation", and believes that its main pathogenesis is kidney deficiency and imbalance of yin and yang. Therefore, traditional Chinese medicine prescriptions or traditional Chinese and Western compound preparations are often used clinically to treat the disease. Medications for kidney deficiency can invigorate the kidney...

Claims

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Application Information

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IPC IPC(8): A61K36/9068A61P15/12A61K35/618
Inventor 叶宗耀
Owner 叶宗耀
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