Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

A 3D printed artificial skull patch and preparation method thereof

A technology of 3D printing and patch, which is applied in the field of 3D printed artificial skull patch and its preparation, can solve the problems of increasing operation time, affecting the appearance, weakening the strength of titanium alloy mesh, etc., to solve the problem of biocompatibility , High matching degree of shape and size, and the effect of inducing bone cell growth

Active Publication Date: 2018-10-30
FOURTH MILITARY MEDICAL UNIVERSITY +1
View PDF6 Cites 0 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

This kind of operation puts forward very high requirements for the doctor. The doctor must manufacture the restoration on the operating table as soon as possible according to the shape of the patient's skull defect. However, since the shape of each patient's skull defect is different, the restoration material titanium alloy is not easy to form. As a result, the titanium plate for skull repair prepared by hand does not fit well with the patient's skull defect, and some parts are sometimes warped, which affects the appearance; and repeated cutting of the titanium alloy mesh plate will weaken its strength and increase the use of titanium alloy screws. Increased cost of surgical treatment
Due to the need to repeatedly shape the titanium plate during the operation, the operation time is increased, the wound exposure time is increased, and the risk of postoperative infection is also increased. Once infection occurs, it may mean that the operation fails. The built-in skull repair titanium plate needs Take out, or need to operate again, which increases the trauma and economic burden of the patient

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • A 3D printed artificial skull patch and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0037] A preparation method of a 3D printed artificial skull patch, specifically comprising the following steps:

[0038] 1. Data collection

[0039] Obtain the patient's preoperative skull image data, and then input the data into the 3D software for 3D reconstruction, complete the design of the artificial skull patch, and obtain the 3D data of the artificial skull patch.

[0040] 2. Raw material preparation

[0041] 2.1 Grind the autologous bone into powder at -15°C, and then pass refining and sieving to screen the autologous bone powder with a particle size of 100 μm;

[0042] 2.2 Prepare 0.2mol / L CaCl 2 Solution 20mL, according to the ratio of Ca / P molar ratio is 1.67, CaCl 2 The solution was slowly dropped into 24mL of 0.1mol / L H 3 PO 4 solution, and then use sodium hydroxide solution to adjust the pH value to 7-10 to form a gel of calcium hydroxyphosphate. After aging for 24 hours, wash it, then dry it in a drying oven at 105°C for 2 days, grind and sieve Finally, c...

Embodiment 2~7

[0050] Embodiment 2~7 and comparative example 1~6

[0051] The preparation method steps and mechanical property testing methods of Examples 2-7 and Comparative Examples 1-6 are the same as Example 1, and the difference from Example 1 lies in the particle size (A) of autologous bone powder and the particle size (B) of calcium hydroxyphosphate. ), the mass ratio (C) of autologous bone powder and calcium hydroxyphosphate and the mass ratio (D) of the mass of the powder material to the volume of the dilute phosphoric acid (D), its specific parameters and mechanical properties are shown in Table 1:

[0052] Table 1

[0053]

[0054] control sample

[0055] The preparation method steps and mechanical property testing method of the control sample are the same as those in Example 1. The difference from Example 1 is that the control sample only uses calcium hydroxyphosphate with a particle size of 120 μm as the raw material of the 3D printing powder, without adding autologous bone ...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

PropertyMeasurementUnit
particle diameteraaaaaaaaaa
particle diameteraaaaaaaaaa
particle diameteraaaaaaaaaa
Login to View More

Abstract

The invention provides an artificial skull repairing piece and a preparation method thereof. A 3D printing technology is adopted in the preparation method; autologous bone powder and hydroxyl calcium phosphate are used as basic raw materials of the artificial skull repairing piece, and thus the problem in biocompatibility of the artificial skull repairing piece is effectively solved; the outline dimension matching degree between the 3D printed artificial skull repairing piece and the defect part is high, and thus the working strength of doctors is greatly reduced; with good biocompatibility, the artificial skull repairing piece is conducive to inducing bone cell growth and promoting repairing; and due to high mechanical strength, the operation safety is improved.

Description

technical field [0001] The present invention relates to the field of artificial skull prostheses, and more specifically, to a 3D printed artificial skull prosthesis and a preparation method thereof. Background technique [0002] Skull defects caused by various reasons, such as craniocerebral trauma surgery or brain tumor surgery to remove the skull bone flap, due to the change in the shape of the skull defect area, the scalp is affected by the atmospheric pressure, causing its invagination to compress the brain tissue, seriously affecting brain function, and Without the protection of the skull, the brain is extremely vulnerable to re-injury. Therefore, it is necessary to perform cranioplasty 3-6 months after craniectomy. [0003] At present, the commonly used skull repair materials can be divided into two categories: autologous bone and artificial materials. Among them, autologous bone is mainly used for autologous bone transplantation. Although autologous bone has good b...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Patents(China)
IPC IPC(8): A61F2/28A61L27/12A61L27/36
CPCA61F2/2875A61F2002/2835A61F2310/00293A61F2310/00359A61L27/12A61L27/3608A61L27/365A61L2430/02
Inventor 费舟罗百顺陈红庆袁玉宇
Owner FOURTH MILITARY MEDICAL UNIVERSITY
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com