Composition capable of achieving sun protection and preventing infection of mosquito-borne viruses such as Zika virus
A technology of virus infection and composition, applied in the field of formulation of pharmaceutical preparations, can solve problems such as poor prognosis, abnormal development of fetal nervous system, heavy burden on patients' families, etc.
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Embodiment 1
[0031] Mix 10g menthol, 10g borneol, 10g Phellodendron cortex, 10g eggshell membrane paste, 25g lavender oil, 15g monoglyceride, 5g BAAPE, 5g sodium citrate, 5g di-tert-butyl p-cresol, 5g diazoimidazolidine Base urea and 150g of distilled water are dissolved in 700g of 95% alcohol, and then 50g of essence is added to prepare 1kg of base.
[0032] Add 150 g of zinc glycerol, 50 g of gossypol, and 100 g of ascorbyl stearate to 700 g of the base, and stir while adding, so that they are evenly dispersed in the base, and continue stirring for 30 minutes after the addition is complete to obtain a paste.
[0033] The ointment base is diluted according to the ratio of ointment: base = 10:0, 1:1, 1:9, and prepared into preparations with different drug content concentrations for testing.
Embodiment 2
[0035] Dissolve 50g essence, 10g menthol, 30g eggshell membrane powder, 25g lavender oil, 15g Tween, 25g DEET, 5g sodium citrate, 5g di-tert-butyl p-cresol, 5g allantoin, 100g distilled water in 700g cottonseed oil In, then add 50g glycerin, deploy into 1kg oily base.
[0036] Add gossypol 50g and ascorbyl palmitate 100g in this oily base 750g, stir while adding, make them disperse evenly in the oily base. Then continue to stir, add zinc oxide 100g while stirring, continue to stir for 30min after adding, promptly obtain ointment.
[0037] The ointment is diluted with an oily base according to the ratio of ointment: oily base=10:0, 1:1, 1:9, and prepared into preparations with different drug content concentrations for testing.
Embodiment 3
[0039] 40 healthy volunteers were randomly selected, and with reference to the "People's Republic of China Sunscreen Cosmetics Sunscreen Factor (SPF) Measurement Method", the sunscreen effect of the preparations obtained in Example 1 and Example 2 was measured for SPF.
[0040] The results show that each preparation has a good sunscreen effect, and the SPF values corresponding to the preparations made from the ointment are respectively 46 for the ointment, 25 for the 1:1 preparation, and 13 for the 1:9 preparation; Ointment 60, 1:1 preparation 30, 1:9 preparation 15, respectively.
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