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Molecular imprinting electrochemical sensor for detecting trace bisphenol A

A molecular imprinting and electrochemical technology, which is applied in the fields of material electrochemical variables, measuring devices, scientific instruments, etc., to achieve the effect of improving sensitivity and selectivity

Inactive Publication Date: 2016-12-07
ZHAOQING UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

However, there is no report on the use of reduced graphene oxide-doped palladium-modified electrodes for the detection of BPA.

Method used

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  • Molecular imprinting electrochemical sensor for detecting trace bisphenol A
  • Molecular imprinting electrochemical sensor for detecting trace bisphenol A
  • Molecular imprinting electrochemical sensor for detecting trace bisphenol A

Examples

Experimental program
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Effect test

Embodiment 1

[0020] Example 1: Construction of a molecularly imprinted electrochemical sensor for detecting trace amounts of BPA according to the present invention

[0021] (1) Treatment of glassy carbon electrodes:

[0022] Polish the glassy carbon electrode on the suede with 0.05 μm alumina polishing powder, then wash it with 2.0M sulfuric acid, distilled water, and absolute ethanol in sequence, and then stabilize it by cyclic voltammetry scanning in 5.0mM potassium ferricyanide solution, take out Rinse with distilled water and let dry for later use.

[0023] (2) Preparation of rGO@Pd modified electrode:

[0024] Weigh 5.0mg rGO@Pd, disperse it in 2.0mL N,N-dimethylformamide solution, ultrasonically disperse it for 15min, take 4.0μL drop-coated on the surface of the glassy carbon electrode, and dry it under the infrared lamp for use.

[0025] (3) Preparation of BPA molecularly imprinted electrode:

[0026] A certain amount of BPA and pyrrole were respectively dissolved in acetonitrile...

Embodiment 2

[0027] Example 2: Cyclic voltammetry characterization of the molecularly imprinted electrochemical sensor for detecting trace amounts of BPA according to the present invention

[0028] Since the imprinted holes in the membrane can serve as channels for electron transfer, using K 3 Fe(CN) 6 As a probe, characterize the surface properties of various electrodes according to the magnitude of their current. Such as figure 1 As shown, different electrodes at K 3 Fe(CN) 6 The cyclic voltammograms in solution differ significantly.

[0029] Curve a is the cyclic voltammogram of the bare gold electrode. When the reduced graphene oxide is modified on the electrode surface, the redox peak current of potassium ferricyanide increases (curve b). When palladium is further doped, the redox peak current of potassium ferricyanide further increases due to the signal amplification effect of the nanobar (curve c). After the electrode is polymerized in the solution containing BPA and pyrrole, ...

Embodiment 3

[0030] Example 3: SEM characterization of different modified electrodes of the molecularly imprinted electrochemical sensor used to detect trace amounts of BPA according to the present invention

[0031] The microstructure of different modified electrodes was characterized by scanning electron microscopy. Such as figure 2 As shown, after the surface of the electrode is modified with a molecularly imprinted membrane (A), the molecularly imprinted membrane is evenly distributed on the electrode surface; after elution, because the template molecules are eluted, holes are left on the surface of the molecularly imprinted membrane , so the surface becomes rough (B).

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PUM

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Abstract

The invention relates to a molecular imprinting electrochemical sensor for detecting trace bisphenol A. A glassy carbon electrode is modified with reduced graphene oxide doped with palladium (rGO@Pd), and electropolymerization is carried on the modified electrode by using pyrrole as a functional monomer and bisphenol A (BPA) as a template molecule to obtain the BPA molecular imprinting electrochemical sensor. When the BPA is within a concentration range of 1.0 nM to 10.0 nM, electrochemical signal rise level is in good linear relation with BPA concentration, and a process detection limit is 0.1 nM. The molecular imprinting electrochemical sensor for detecting trace bisphenol A overcomes the defects that the prior art methods for detecting BPA are complicated and the steps are difficult, detection sensitivity and selectivity are better improved, and it is easy to automate the detection of low-concentration BPA.

Description

technical field [0001] The invention belongs to the technical field of novel functional materials and electrochemical sensing and detection, and relates to a molecularly imprinted electrochemical sensor, in particular to a molecularly imprinted electrochemical sensor for detecting trace amounts of bisphenol A (BPA). Background technique [0002] Bisphenol A (BPA) is an organic compound that is often used in industry. It can be used as a monomer in the plastics industry to produce epoxy resins and polycarbonates, and is widely used in the manufacture of infant feeding bottles, beverage containers, and food packaging. Because the chemical structure of BPA is similar to estradiol and ethylene estradiol, it has the same effect as other environmental hormones, can imitate or interfere with endogenous estrogen, play a role in mimicking estrogen, and affect the reproduction, growth and development of organisms, the nervous system, Detrimental effects on the immune system and many o...

Claims

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Application Information

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IPC IPC(8): G01N27/30G01N27/31
CPCG01N27/308G01N27/31
Inventor 汪洪武刘艳清姚夙马国坚韦寿莲严子军
Owner ZHAOQING UNIV
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