Device and method for endovascular optical coherence tomography - opto-acoustic - ultrasonic multimode imaging

Abstract

The invention belongs to the field of blood vessel endoscopic imaging and discloses a device and method for endovascular optical coherence tomography - opto-acoustic - ultrasonic multimode imaging. The device comprises a computer, an optical coherence tomography (OCT) excitation and collection system, an opto-acoustic signal excitation and collection system, an ultrasonic signal excitation and collection system and an integrated probe. The OCT excitation and collection system comprises a field programmable logic array (PFGA) panel, a superluminescent diode, an isolator, a first optical fiber coupler, a reference arm, a linear array charge coupled device (CCD) and a first collecting card. The opto-acoustic signal excitation and collection system comprises a pulsed laser, a diaphragm, a second optical fiber coupler and a doubly clad optical fiber. The ultrasonic signal excitation and collection system comprises a pulse ultrasonic emitter / receiver, a signal amplifier, a signal filter and a second collecting card. The OCT, opto-acoustic and ultrasonic tri-modal blood vessel endoscopic imaging system integrates three imaging modes and respective advantages thereof, and multi-parameter physiological function information and multiscale structural information of a blood vessel can be obtained.

Description

technical field [0001] The invention relates to the research field of vascular endoscopy, in particular to an intravascular optical coherence tomography-photoacoustic-ultrasound multimode imaging device and method. Background technique [0002] Cardiovascular and cerebrovascular diseases are diseases with a high mortality rate, and the accuracy of blood vessel detection has higher requirements. There are modern medical methods for detecting blood vessels, including magnetic resonance (MRI) angiography, angiographic imaging (IVUS) and intravascular optical coherence tomography (OCT). The above detection methods can better present the external shape of blood vessels or internal contours, but cannot provide local details of the vessel wall and lumen. Intravascular photoacoustic imaging technology is a new type of medical imaging technology. The main principle is to irradiate tissue with pulsed laser light, and the tissue absorbs the light to generate thermoelastic waves. By im...

AI Technical Summary

Problems solved by technology

The end of the optical fiber of this device directly emits light at 90°, the laser is divergently irradiated on the object to be measured, the laser is not converged, and there is also the problem of poor resolution of the photoacoustic image, and in the device disclosed in this technology, the coupling of the laser and the optical fiber is adopted The way of direct coupling, in this way, the deviation is very easy to occur during the rotation of the fiber, which leads to the reduction of the transmission efficiency of the laser to the fiber, and directly affects the generation of photoacoustic signals

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