Blue shark skin collagen compound gel preparation and preparation method and application thereof

A composite gel and gel preparation technology, applied in the field of medical biomaterials, can solve problems such as incompletely clear etiology, unsatisfactory effects, ulcer tissue inflammation, etc., achieve low mucosal irritation, reduce congestion and edema, and increase additional value effect

Inactive Publication Date: 2017-05-24
上海麦琳生物医学工程科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The pathological changes of oral ulcers are mainly ulcerative lesions in the local oral mucosa. The pathogenesis is extremely complex, which is related to many factors such as genetic factors and immune factors. It has the characteristics of periodic and burning pain. Tissue inflammation and necrosis,

Method used

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  • Blue shark skin collagen compound gel preparation and preparation method and application thereof
  • Blue shark skin collagen compound gel preparation and preparation method and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0051] Embodiment 1, a kind of blue shark skin collagen composite gel preparation, this gel preparation is made up of the following components by weight percentage:

[0052] Blue Shark Skin Collagen 9%;

[0053] Chitosan 2.25%;

[0054] The balance is gel base.

Embodiment 2

[0055] Embodiment 2, a kind of blue shark skin collagen composite gel preparation, this gel preparation is made up of the following components by weight percentage:

[0056] Blue Shark Skin Collagen 3%;

[0057] Chitosan 0.75%;

[0058] The balance is gel base.

Embodiment 3

[0059] Embodiment 3, a kind of blue shark skin collagen composite gel preparation, this gel preparation is made up of the following components by weight percentage:

[0060] Blue Shark Skin Collagen 1%;

[0061] Chitosan 0.25%;

[0062] The balance is gel base.

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Abstract

The invention discloses a blue shark skin collagen compound gel preparation. The blue shark skin collagen compound gel preparation is characterized in that the gel preparation comprises the following components by weight percent: 1-9% of blue shark skin collagen, 0.25-2.25% of chitosan, and the balance of a gel matrix. The invention further provides a preparation method of the gel preparation. The gel preparation can be used to rehabilitate a wound surface in an oral cavity.

Description

technical field [0001] The invention belongs to the field of medical biomaterials, and relates to a gel preparation, in particular to a blue shark skin collagen composite gel preparation and a preparation method and application thereof. Background technique [0002] Aquatic collagen is a natural biopolymer material with low antigenicity, hemostatic properties, and bioabsorbability. It can provide continuous and slow drug delivery to wounded skin spongy tissue, promote granulation growth, prevent rebleeding, and promote wound healing. heal. [0003] Chitosan is a natural alkaline polysaccharide existing in nature, and it is a deacetylated product of chitin. The content of chitin in nature is second only to cellulose, and it has a wide range of sources. As a natural polymer material, chitosan has good biocompatibility, degradability, antibacterial properties, healing promotion, non-toxic, non-irritating to mucous membranes, and can promote mucous membrane adhesion. In the fie...

Claims

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Application Information

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IPC IPC(8): A61K38/39A61K9/06A61P1/02A61K31/722
CPCA61K9/06A61K31/722A61K38/39A61K47/38A61K2300/00
Inventor 蒋升徐晓刚李铁军吴文惠杨桥王淑军吕明生缪辉南
Owner 上海麦琳生物医学工程科技有限公司
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