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Drug combination for treating prosopalgia

A technology for trigeminal neuralgia and composition, which can be used in drug combinations, nervous system diseases, antipyretics, etc., and can solve the problems of easy recurrence, large side effects and high risks

Inactive Publication Date: 2017-12-01
臧运华
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The more commonly used clinical methods are mostly focused on neurosurgical treatment. Peripheral branch avulsion, amputation, and trigeminal spinal cord amputation are not suitable for patients of all ages, and they are relatively painful, high-risk, and costly; In the field of neurology in the field of western medicine, most of the symptoms can only be passively controlled and relieved by taking carbamazepine or alcohol injection, but the treatment effect is poor, the recovery period is long, and it is easy to relapse. Carbamazepine, the first choice drug for trigeminal neuralgia Long-term use of the drug is difficult due to large side effects or high risks

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0042] Example 1: Measure centipede, toad venom, tortoise shell, Yuanhu, dried blood, bezoar, bear bile, Nansha ginseng, Gansong, Chuanbei, Polygonatum odoratum, Vitex, cinnamon, lark, dodder, hippocampus decoction pieces according to the formula , crushed into powdered medicine, passed through a 50-mesh sieve, soaked the sieved powdered medicine in deionized water at 45°C for half an hour, filtered with gauze to obtain the medicinal residue, wrapped the medicinal residue with the gauze and tied the mouth, put it into the automatic In the decoction machine, add 2500g of water, decoct under normal temperature and pressure for 3 hours, remove the medicine bag, and divide the obtained medicinal liquid to obtain decoction A.

Embodiment 2

[0044] (1) Monarch drug decoction: Take centipede, toad venom, and tortoise shell decoction pieces twice as much as the formula, crush them into powder and pass through a 100-mesh sieve, soak the sieved powder in deionized water at 45°C for 1 hour, and then use The medicinal mud is obtained by filtering with a double-layer non-woven fabric, wrapping the medicinal mud with the double-layer non-woven fabric and tying the mouth, putting it into an automatic decoction machine, adding 200g of water, and decocting for 1 hour at a working pressure of 170kPa and a temperature of 130°C , remove the non-woven drug bag, add 10g honey to the medicinal liquid, continue to decoct for 2 hours under normal temperature and pressure difference, until the medicinal liquid is concentrated into a paste, and the monarch drug ointment is obtained;

[0045] (2) Decoction of ministerial medicine: take the decoction pieces of Yuanhu, blood dried fruit, bezoar, and bear bile in the prescribed amount, cru...

Embodiment 3

[0050] (1) Pre-treatment of raw materials: take three times the amount of the formula for centipede, toad, and tortoise shell; take twice the amount of the formula for Yuanhu, Xuegan, bezoar, and bear bile; take Nansha ginseng, Gansong, Chuanbei, and jade Bamboo, vitex, cinnamon, lark, dodder, hippocampus, pulverized and mixed, added 1200g deionized water, decocted at normal temperature and pressure for 6 hours, filtered to obtain a medicinal solution, and added 800g deionized water to the filter residue , decocted at a pressure of 80kPa and a temperature of 120°C for 4 hours, filtered to obtain a second medicinal solution, then added 400g of deionized water to the residue, decocted at a pressure of 170kPa and a temperature of 130°C for 2 hours, and filtered to obtain a third medicinal solution ; Combine the first, second and third medicinal liquids above, add 300g honey to the combined medicinal liquid, continue to decoct for 3 hours under normal temperature and differential p...

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PUM

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Abstract

The invention relates to a drug combination for treating prosopalgia. The drug combination is prepared from the following raw materials of centipedes, venenum bufonis, tortoiseshell, rhizoma corydalis, resina draconis, calculus bovis, bear bile, adenophora tetraphylla, rhizoma nardostachyos, bulbus fritillariae cirrhosae, radix polygonati officinalis, fructus viticis, cinnamon, marsdenia longipes, semen cuscutae and hippocampi, wherein the centipedes, the venenum bufonis and the tortoiseshell are sovereign drugs, the rhizoma corydalis, the resina draconis, the calculus bovis and the bear bile are ministerial drugs, the adenophora tetraphylla, the rhizoma nardostachyos, the bulbus fritillariae cirrhosae and the radix polygonati officinalis are adjuvant drugs, and the fructus viticis, the cinnamon, the marsdenia longipes, the semen cuscutae and the hippocampi are conductant drugs. The drug combination prescription for treating prosopalgia is simplified in drug, the drugs are mutually coordinated while taking effects respectively and have the unexpected technical effect on treating prosopalgia after being compounded together, currently, more than 300 various patients are cured, and the effective rate can be 97% or above. The drug combination has the advantages that the effect is taken rapidly, the efficiency is high, the treatment course is short, and relapses are not likely to occur; and in addition, the specific four-image separate preparation process is easy to master and apply.

Description

technical field [0001] The invention relates to the technical field of traditional Chinese medicine, relates to a neurology medicine, in particular to a medicine composition for treating trigeminal neuralgia. Background technique [0002] Trigeminal neuralgia is a common disease in neurology. It is characterized by recurrent paroxysmal severe pain in the trigeminal nerve distribution area on one side of the face. The symptoms are characterized by sudden onset and sudden arrest in the trigeminal nerve distribution area of ​​the head and face. , Lightning-like, knife-like, burning-like, intractable, unbearable severe pain, which affects normal life and work. According to domestic statistics, the incidence rate of this disease is about 52 cases per 100,000 people. The more commonly used clinical methods are mostly focused on neurosurgical treatment. Peripheral branch avulsion, amputation, and trigeminal spinal cord amputation are not suitable for patients of all ages, and they ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/8969A61P29/00A61P25/02A61K35/65A61K35/648A61K35/60A61K35/586A61K35/413
CPCA61K9/0095A61K35/413A61K35/586A61K35/60A61K35/648A61K35/65A61K36/27A61K36/342A61K36/39A61K36/43A61K36/54A61K36/66A61K36/84A61K36/85A61K36/889A61K36/896A61K36/8966A61K36/8969A61K2236/331A61K2236/39A61K2236/51A61K2300/00
Inventor 臧运华高向慧郑志轩王群周喜燕
Owner 臧运华