Chinese herbal pieces processed by enzymes and preparation method of Chinese herbal pieces

A technology for decoction pieces of traditional Chinese medicine and enzyme treatment, which can be used in pharmaceutical formulations, medical preparations containing active ingredients, plant raw materials, etc., can solve problems such as differences in berberine content, and achieve the effects of convenient taking, simple preparation method and significant curative effect.

Inactive Publication Date: 2018-01-19
GUANGXI UNIV OF CHINESE MEDICINE
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AI Technical Summary

Problems solved by technology

[0020] Ma Juyun, Zhao Jingyan, etc. selected Coptis Rhizoma to extract berberine, and studied the effect of its enzyme-added group and non-enzyme-added group on the extraction of active ingredient berberine. Compared with the original process, the new process is just one more step to add cellulase Enzymatic hydrolysis process, but the content of berberine extracted by the two processes is significantly different, while the extracted components are the same

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1 4

[0062] Example 1 Sijunzi Decoction Chinese medicine extraction, the Sijunzi Decoction is composed of the following raw materials in parts by weight: Codonopsis 30-50; Atractylodes Rhizome 30-50; Licorice 5-10; Poria 30-50.

[0063] Codonopsis pilosula, Atractylodes macrocephala, licorice, and Poria cocos are crushed separately, and then extracted with enzymes.

[0064] Codonopsis pilosula is made of plant rhizome fiber Chinese medicinal materials: two or more enzymes of cellulase, xylanase, amylase, and glucoamylase are used to extract;

[0065] Atractylodes macrocephala adopts plant rhizome fiber Chinese herbal medicine: it is extracted by two or more enzymes of cellulase, xylanase, amylase and glucoamylase;

[0066] Licorice uses plant rhizome fiber Chinese herbal medicines: two or more enzymes of cellulase, xylanase, amylase, and glucoamylase are used to extract;

[0067]Poria cocos is extracted by enzymes from starchy Chinese medicinal materials: two or more enzymes of am...

Embodiment 2

[0074] Huanglian Jiedu Decoction, the dosage of Huanglian Jiedu Decoction, Coptidis 9g, Scutellaria baicalensis 6g, Phellodendron 6g, Gardenia 9g.

[0075] Huanglian Jiedu Decoction, the name of a traditional Chinese medicine prescription. As a heat-clearing agent, it has the effect of clearing heat and detoxifying. Indications triple burner fire poison syndrome. Severe fever and irritability, dry mouth and throat, wrong speech and insomnia; or febrile disease with hematemesis and epistaxis; Yellow-red urine, red tongue with yellow fur, and strong pulse. Clinically, it is often used to treat patients with heat toxicity such as sepsis, sepsis, dysentery, pneumonia, urinary tract infection, epidemic cerebrospinal meningitis, and Japanese encephalitis.

[0076] Four flavors of Qingrejiedu decoction, Scutellaria baicalensis, Phellodendron japonica, manic fever, vomiting and insomnia, vomiting of bleeds and hair spots can be used.

[0077] Composition, coptis, scutellaria, cort...

Embodiment 3

[0090] Example 3, Ganoderma lucidum and Salvia miltiorrhiza Proven prescription for treating coronary heart disease

[0091] Prescription: Ganoderma lucidum 15 grams, Salvia miltiorrhiza 20 grams, Chuanxiong 10 grams, Acanthopanax 20 grams; the traditional extraction method is to add five flavors to 3-5 times of water, boil for 2-4 hours, filter, and add 2 times of water to the obtained medicinal residues Boil for 1-2 hours, combine the medicinal liquids, concentrate them into oral liquids, or concentrate them into pastes, add auxiliary materials, and make capsules or tablets.

[0092] The above-mentioned proven prescriptions have the effects of enhancing myocardial contraction, improving blood circulation, reducing myocardial oxygen consumption, nourishing the myocardium, improving heart function, lowering blood sugar, etc., and are mainly used to treat angina pectoris, arrhythmia, myocardial infarction, coronary heart disease, etc.

[0093] But the above-mentioned water extr...

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PUM

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Abstract

Disclosed is a preparation method of Chinese herbal pieces processed by enzymes. The preparation method comprises the steps that firstly, single Chinese herbal medicines are extracted by using the enzymes according to Chinese herbal medicines of different categories, then medicine dregs are filtered, the medicine dregs are extracted by water/alcohol secondarily, seperatefiltrating taking and concentrating are conducted, and the Chinese herbal pieces of various forms or water-insoluble (dispersed) granules are processed; more than one of cellulase enzymes, xylanase, amylase and saccharifying enzymes is used; (2) more than one of protease, pancreatic enzymes, lipase and beta-dextranase in the Chinese herbal medicines of animals is used; (3) more than one of amylase, glucose oxidase, catalaseand beta-dextranase in the Chinese herbal medicines of starch is used; and (4) more than one of cellulase enzymes, pectinase, saccharifying enzymes and beta-dextranase in the Chinese herbal medicinesof fruit is used. According to the preparation method of the Chinese herbal pieces processed by the enzymes, the extraction rate of Chinese herbal ingredients extracted by the enzymes is increased by20-30% than that of an ordinary water extracting method and alcohol-water extracting method, and the preparation method has the advantages of being pollution-free and fully using limited resources.

Description

technical field [0001] The invention relates to the field of extraction technology and application of traditional Chinese medicine, in particular to a Chinese medicine decoction piece prepared by enzymatic treatment of a single Chinese medicine or a traditional Chinese medicine prescription and a preparation method thereof. Background technique [0002] Traditional Chinese medicine is the treasure of the Chinese nation. Thousands of years ago, the ancient Chinese knew how to use traditional Chinese medicine to treat diseases. From the Yellow Emperor's Internal Classic to the Compendium of Materia Medica, all of them shine with the light and wisdom of the Chinese nation, enabling the Chinese nation to thrive in health and have a splendid culture. And history, since the founding of the People's Republic of China, especially since my country's reform and opening up, China has made great achievements in the use of Chinese herbal medicine to treat various diseases. Many diseases th...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/00B01D11/02
Inventor 梁健钦岳桂华张爱珍马晓聪熊万娜
Owner GUANGXI UNIV OF CHINESE MEDICINE
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