Chitosan oligosaccharide throat-soothing oral tablet and preparation method thereof

A chitosan oligosaccharide and tabletting technology, which is applied in confectionery, confectionary industry, pharmaceutical formulations, etc., can solve problems such as unfavorable blood sugar control

Inactive Publication Date: 2018-04-20
GUANGDONG MEDICAL UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the main additives include glucose, sucrose and other...

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0022] Embodiment 1: The present invention relates to a kind of chitosan oligosaccharide throat moistening oral cavity compression tablet, comprises each component of following parts by weight, chitosan oligosaccharide 100 milligrams, fructose 80 milligrams, green fruit extract 30 milligrams, black plum extract 30 milligrams, hang Chrysanthemum extract 30 mg, maltodextrin 5 mg, microcrystalline cellulose 5 mg, hydroxypropyl methylcellulose 5 mg, sodium carboxymethyl cellulose 5 mg, lecithin 40 mg.

[0023] The preparation method of described chitosan oligosaccharide moistens throat oral tablet, comprises the following steps:

[0024] (1) Weigh each part by weight according to the proportioning ratio;

[0025] (2) Mix all components evenly;

[0026] (3) Put it into a tablet press and press it;

[0027] (4) Dry the compressed tablet on a dryer;

[0028] (5) disinfection;

[0029] (6) Packed into boxes.

Embodiment 2

[0030] Embodiment 2: The present invention relates to a kind of chitosan oligosaccharide throat moistening oral cavity compression tablet, comprises each component of following parts by weight, described chitosan oligosaccharide 200 milligrams, fructose 100 milligrams, green fruit extract 50 milligrams, dark plum extract 50 milligrams mg, 50 mg of Chrysanthemum chrysanthemum extract, 10 mg of maltodextrin, 10 mg of microcrystalline cellulose, 10 mg of hydroxypropyl methylcellulose, 10 mg of sodium carboxymethyl cellulose, 50 mg of lecithin, the preparation method is the same as the implementation example 1.

Embodiment 3

[0031] Embodiment 3: The present invention relates to a kind of chitosan oligosaccharide throat moistening oral cavity compression tablet, comprises each component of following parts by weight, chitosan oligosaccharide 300 milligrams, fructose 120 milligrams, green fruit extract 100 milligrams, black plum extract 80 milligrams, hang 80 mg of chrysanthemum extract, 15 mg of maltodextrin, 15 mg of microcrystalline cellulose, 15 mg of hydroxypropyl methylcellulose, 15 mg of sodium carboxymethyl cellulose, and 60 mg of lecithin. The preparation method is the same as in Example 1.

[0032] Clinical cases: A total of 200 patients were observed, taking buccal tablets 3 times a day, 1 tablet each time, for 10 consecutive days. The diagnostic criteria are all in line with the diagnostic criteria of the "Guiding Principles for Clinical Research of New Drugs (Chinese Medicines) in the Treatment of Chronic Pharyngitis" formulated by the Pharmaceutical Administration Bureau of the Ministry ...

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PUM

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Abstract

The invention relates to a chitosan oligosaccharide throat-soothing oral tablet and a preparation method of the chitosan oligosaccharide throat-soothing oral tablet. The chitosan oligosaccharide throat-soothing oral tablet comprises the following various components by weight: 100-300 mg of chitosan oligosaccharide, 80-120 mg of fructose, 30-100 mg of Chinese olive extract, 30-80 parts of smoked plum extract, 30-80 mg of chrysanthemum morifolium extract, 5-15 mg of maltodextrin, 5-15 mg of microcrystalline cellulose, 5-15 mg of hydroxypropyl methyl cellulose, 5-15 mg of sodium carboxymethylcellulose, and 40-60 mg of lecithin. The chitosan oligosaccharide throat-soothing oral tablet has the advantages that the requirement of market health of chronic pharyngitis and dental ulcer is met, the effects are obvious, the chitosan oligosaccharide throat-soothing oral tablet is strong in pertinence and is convenient to store, and the preparation method is simple and feasible.

Description

technical field [0001] The invention relates to a throat-moistening oral tablet of chitosan oligosaccharide and a preparation method thereof, belonging to the technical field of health-care candies. Background technique [0002] Chronic pharyngitis is the most common disease among throat diseases. The common clinical symptoms are: sore throat, throat discomfort, foreign body sensation, cough, throat secretions are not easy to spit out, nausea and vomiting, throat dry itching, burning sensation, dryness or symptoms such as irritation. The lesions involve upper respiratory tract lesions adjacent to the pharynx, changes in temperature and humidity, poor air quality, stimulation by tobacco and alcohol, spicy and irritating food, dust, etc., allergies and other factors. The incidence rate of various oral diseases in my country is as high as 97.6%, 20% of which are oral ulcers, most of which are recurrent, and the burning and pain caused by ulcers are really troublesome. The inc...

Claims

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Application Information

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IPC IPC(8): A61K36/736A61K31/722A61K9/20A61K47/26A61P1/02A61P11/04A23G3/42A23G3/48A23G3/36
CPCA61K36/32A23G3/364A23G3/42A23G3/48A23V2002/00A61K9/2018A61K31/722A61K36/287A61K36/736A23V2200/314A23V2250/511A23V2250/28A23V2250/606A23V2250/5114A23V2250/21A23V2250/51082A23V2250/51084A23V2250/1842
Inventor 戚怡于丰彦罗辉安伯超梁力中李林科
Owner GUANGDONG MEDICAL UNIV
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