Xiaojin rubber plaster as well as preparation method and application thereof

A plaster and rubber technology, which is applied in the field of Xiaojin rubber plaster and its preparation and application, can solve the problems of not being able to quickly relieve symptoms and other treatment effects, and achieve the effects of fast onset, good stability, and good coating effect

Inactive Publication Date: 2018-08-03
CHENGDU UNIV OF TRADITIONAL CHINESE MEDICINE
View PDF2 Cites 5 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] However, Xiaojin Pills uses raw medicinal materials to powder into medicine, and the way of administration is oral, which cannot quickly exert anti-inflammatory and analgesic effects on the corresponding lesions, and cannot achieve the therapeutic effect of quickly relieving symptoms.

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Xiaojin rubber plaster as well as preparation method and application thereof
  • Xiaojin rubber plaster as well as preparation method and application thereof
  • Xiaojin rubber plaster as well as preparation method and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0044] Embodiment 1 The preparation of Xiaojin rubber plaster of the present invention

[0045] 1. Preparation of Xiaojin Extract

[0046] The dried Xiaojin medicine powder is extracted with 40% ethanol aqueous solution as a solvent, the ratio of solid to liquid is 1:12, the extraction time is 3 hours, and the extract is concentrated to obtain an extract.

[0047] 2. Weigh raw and auxiliary materials

[0048]

[0049] 3. Preparation method

[0050] 1) Rubber mixing: Take natural rubber, cut it into small pieces, put it into the rubber mixing machine, and refine it into mesh flakes.

[0051] 2) Mixing: take lithopone and solid tackifier rosin, mix and pulverize into coarse powder, add liquid tackifier cyclopentadiene, softener cyclopentadiene, vaseline, lanolin, add step 1) obtained mesh Thin slices of natural rubber are uniformly mixed to obtain a plaster base, and Xiaojin extract is added to the plaster base for mixing and refining.

[0052] 3) Coating: coating the dru...

Embodiment 2

[0054] Embodiment 2 The preparation of Xiaojin rubber plaster of the present invention

[0055] 1. Preparation of Xiaojin Extract

[0056] The dried Xiaojin medicine powder is extracted with 30% ethanol aqueous solution as a solvent, the ratio of solid to liquid is 1:10, the extraction time is 2h, and the extract is concentrated to obtain an extract.

[0057] 2. Weigh raw and auxiliary materials

[0058]

[0059] 3. Preparation method

[0060] 1) Rubber mixing: Take natural rubber, cut it into small pieces, put it into the rubber mixing machine, and refine it into mesh flakes.

[0061] 2) Mixing: take lithopone and solid tackifier rosin, mix and pulverize into coarse powder, add liquid tackifier cyclopentadiene, softener cyclopentadiene, vaseline, lanolin, add step 1) obtained mesh Thin slices of natural rubber are uniformly mixed to obtain a plaster base, and Xiaojin extract is added to the plaster base for mixing and refining.

[0062] 3) Coating: coating the drug-conta...

Embodiment 3

[0064] Embodiment 3 Preparation of Xiaojin rubber plaster of the present invention

[0065] 1. Preparation of Xiaojin Extract

[0066] The dried Xiaojin medicine powder is extracted with 50% ethanol aqueous solution as a solvent, the ratio of solid to liquid is 1:15, the extraction time is 4 hours, and the extract is concentrated to obtain extract.

[0067] 2. Weigh raw and auxiliary materials

[0068]

[0069] 3. Preparation method

[0070] 1) Rubber mixing: Take natural rubber, cut it into small pieces, put it into the rubber mixing machine, and refine it into mesh flakes.

[0071] 2) Mixing: take lithopone and solid tackifier rosin, mix and pulverize into coarse powder, add liquid tackifier cyclopentadiene, softener cyclopentadiene, vaseline, lanolin, add step 1) obtained mesh Thin slices of natural rubber are uniformly mixed to obtain a plaster base, and Xiaojin extract is added to the plaster base for mixing and refining.

[0072] 3) Coating: coating the drug-conta...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

PUM

No PUM Login to view more

Abstract

The invention discloses Xiaojin rubber plaster which is prepared from the following raw and auxiliary materials in parts by weight: 6-7 parts of Xiaojin extract, 30-80 parts of natural rubber, 40-60 parts of a tackifier, 20-45 parts of a softening agent and 50-120 parts of a filling agent. The invention further discloses a preparation method of the Xiaojin rubber plaster. The invention also discloses application of the Xiaojin rubber plaster in preparation of medicines for treating hyperplasia of mammary glands, breast cancer, thyroid nodule and thyroid cancer. The Xiaojin rubber plaster disclosed by the invention has the advantages of being smooth in production and processing, good in coating effect, excellent in plaster surface smoothness (fine without blank spots), excellent in bondingproperty, excellent in stability, appropriate in stripping and the like. The Xiaojin rubber plaster disclosed by the invention is fast in efficacy by virtue of transdermal drug delivery, can locally and rapidly achieve the effects of diminishing inflammation and relieving pain at lesions, and has the advantages of being in transdermal delivery ability, long in drug efficacy retention time, high indrug tolerance, safe to use and the like.

Description

technical field [0001] The invention specifically relates to a rubber plaster containing Xiaojin extract and its preparation method and application. Background technique [0002] Xiaojin Wan originated from Wang Hongxu's "Surgical Syndrome and Treatment of Quansheng Ji" in the Qing Dynasty. It is composed of 10 herbs including musk, zhicaowen, wood turtle, maple balm, earthworm, wulingzhi, frankincense, myrrh, angelica, and Jingmo. It has the effect of dispelling stagnation, reducing swelling, removing blood stasis and relieving pain. It is mainly used to treat scrofula, goiter, breast rock, breast addiction and other syndromes caused by phlegm stagnation. It is the first choice of Chinese patent medicine for clinical treatment of breast diseases. Based on comprehensive literature data, it was found that Xiaojin Pills and its medicinal flavors have different degrees of inhibitory effect on the proliferation of tumor cells, and its anti-tumor components are mainly concentrate...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

Application Information

Patent Timeline
no application Login to view more
Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/714A61K9/70A61P5/14A61P15/14A61P35/00A61K33/44A61K35/24A61K35/55A61K35/62
CPCA61K9/7076A61K33/44A61K35/24A61K35/55A61K35/62A61K36/185A61K36/232A61K36/324A61K36/328A61K36/42A61K36/714A61P5/14A61P15/14A61P35/00A61K2300/00
Inventor 韩丽熊茜张定堃张亿慈志敏许润春冯碧
Owner CHENGDU UNIV OF TRADITIONAL CHINESE MEDICINE
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Try Eureka
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap