Alimentary canal gel protective agent and use method and application thereof

A technology of digestive tract and protective agent, applied in the field of food and pharmacy, can solve the problems of loss of intestinal mucosal gel protection function, side effects, harshness, etc.

Inactive Publication Date: 2018-08-28
南京健辉生物科技有限公司
View PDF8 Cites 8 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the above drugs all have side effects, such as causing constipation, toxic accumulation of bismuth and other metals in the human body, etc., and these drugs basically only have a protective effect on the gastric mucosa. Thin film layer will dilute or redissolve, unable to form a stable protective layer
[0003] Chinese Patent Announcement No. CN101411477, CN102727514 and CN101292994 provide gel protective agents made of pectin as the main component, but the conditions for pectin to form gel are more complicated and harsh, and it is difficult to form a stable gel layer in the whole digestive tract. When the gel layer redissolves or only forms a viscous protectiv

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0025] Prepare the gel protectant according to the ratio of sodium alginate: calcium carbonate = 1:0.1 (weight ratio), mix well and prepare a drink according to the following formula.

[0026] Gel protectant 10g

[0027] 60g fructose syrup

[0028] Purified water 1000g

[0029] Dissolved into a uniform suspension at 90°C and then refrigerated to prepare a beverage-type digestive tract gel protector.

Embodiment 2

[0031] Prepare the gel protectant according to the ratio of potassium alginate: iron hydroxide = 1:0.2 (weight ratio), mix well and prepare granules according to the following formula.

[0032] Gel protectant 10g

[0033] 40g white sugar

[0034] 30g whole milk powder

[0035] Non-dairy creamer 20g

[0036] After the above ingredients are uniformly mixed, 100 grams of granules are obtained, brewed with 1000 grams of boiled water, and can be used after being stirred evenly to obtain a solid beverage type digestive tract gel protector.

Embodiment 3

[0038] Prepare the gel protectant according to the ratio of sodium alginate: calcium phosphate = 1:1 (weight ratio), mix well and prepare tablets according to the following formula.

[0039] Gel Protectant 200g

[0040] Citric acid 52g

[0041] Sodium bicarbonate 205g

[0042] Macrogol 6000 20g

[0043] Polyvinylpyrrolidone 10g

[0044] The above ingredients are ground into powder, sieved, blended with polyvinylpyrrolidone as a binder to granulate, dried, sterilized and pressed into tablets. Each tablet weighs 2 grams to obtain an effervescent tablet-type digestive tract gel protector.

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

PUM

No PUM Login to view more

Abstract

The invention relates to the technical field of foods and pharmacy, and provides an alimentary canal gel protective agent. The alimentary canal gel protective agent comprises gels and an acid-solublecross-linking agent, wherein the gels are alginate, and the acid-soluble cross-linking agent is a multivalent metal salt or alkali which is insoluble under a neutral condition and soluble under an acidic condition; in addition, the invention further provides a use method and application of the alimentary canal gel protective agent. The alimentary canal gel protective agent and the use method and application thereof have the advantages that a stable gel protective layer is quickly formed on the gastrointestinal mucous membrane surface after the gel protective agent is taken, the absorption of food compositions by the alimentary canal mucous membrane is blocked or delayed through the modes of 'embedding' and 'isolation', particularly the absorption of fat, cholesterol, glucose, heavy metal ions and ethyl alcohol in the food can be reduced, the effects of losing weight, detoxifying emergently, avoiding alcohol, protecting peptic ulcer, reducing blood fat and protecting glucostasis are achieved, no toxic and side effects exist, the gel protective agent can be made into beverages, dissolved medicines and tablets for use, the production is simple and convenient, and the use is convenient.

Description

technical field [0001] The invention belongs to the technical field of food and pharmacy, and in particular relates to a digestive tract gel protectant and its use method and application. Background technique [0002] Gastrointestinal mucosal protective agents are common drugs used to treat gastrointestinal diseases. For example, bismuth (such as colloidal bismuth pectin, etc.) is deposited on the gastric mucosa in the form of bismuth salts to protect the ulcer surface and exert anti-Helicobacter pylori effects. In addition, there are sucralfate, aluminum magnesium carbonate, bismuth potassium citrate, montmorillonite powder and other drugs, which can quickly attach to the gastric mucosa and lesion surface after oral administration, forming a protective film, so that the local area is no longer affected by gastric acid. It is widely used in the treatment of gastric and duodenal ulcers. However, the above drugs all have side effects, such as causing constipation, toxic accum...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

Application Information

Patent Timeline
no application Login to view more
IPC IPC(8): A61K33/10A61K33/26A61K33/42A61K31/734A61K31/194A61P1/00A61P1/10A23L2/00A23L2/385A23L33/00
CPCA61K33/10A23L2/00A23L2/385A23L33/00A23V2002/00A61K31/194A61K31/734A61K33/26A61K33/42A61K2300/00A23V2200/32A23V2200/3204A23V2200/332A23V2200/30A23V2200/3262A23V2200/328A23V2250/5026A23V2250/606A23V2250/61A23V2250/032A23V2250/5114A23V2250/5112A23V2250/51084A23V2250/612
Inventor 张文辉
Owner 南京健辉生物科技有限公司
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Try Eureka
PatSnap group products