Alimentary canal gel protective agent and use method and application thereof

Abstract

The invention relates to the technical field of foods and pharmacy, and provides an alimentary canal gel protective agent. The alimentary canal gel protective agent comprises gels and an acid-solublecross-linking agent, wherein the gels are alginate, and the acid-soluble cross-linking agent is a multivalent metal salt or alkali which is insoluble under a neutral condition and soluble under an acidic condition; in addition, the invention further provides a use method and application of the alimentary canal gel protective agent. The alimentary canal gel protective agent and the use method and application thereof have the advantages that a stable gel protective layer is quickly formed on the gastrointestinal mucous membrane surface after the gel protective agent is taken, the absorption of food compositions by the alimentary canal mucous membrane is blocked or delayed through the modes of 'embedding' and 'isolation', particularly the absorption of fat, cholesterol, glucose, heavy metal ions and ethyl alcohol in the food can be reduced, the effects of losing weight, detoxifying emergently, avoiding alcohol, protecting peptic ulcer, reducing blood fat and protecting glucostasis are achieved, no toxic and side effects exist, the gel protective agent can be made into beverages, dissolved medicines and tablets for use, the production is simple and convenient, and the use is convenient.

Description

technical field [0001] The invention belongs to the technical field of food and pharmacy, and in particular relates to a digestive tract gel protectant and its use method and application. Background technique [0002] Gastrointestinal mucosal protective agents are common drugs used to treat gastrointestinal diseases. For example, bismuth (such as colloidal bismuth pectin, etc.) is deposited on the gastric mucosa in the form of bismuth salts to protect the ulcer surface and exert anti-Helicobacter pylori effects. In addition, there are sucralfate, aluminum magnesium carbonate, bismuth potassium citrate, montmorillonite powder and other drugs, which can quickly attach to the gastric mucosa and lesion surface after oral administration, forming a protective film, so that the local area is no longer affected by gastric acid. It is widely used in the treatment of gastric and duodenal ulcers. However, the above drugs all have side effects, such as causing constipation, toxic accum...

AI Technical Summary

Problems solved by technology

However, the above drugs all have side effects, such as causing constipation, toxic accumulation of bismuth and other metals in the human body, etc., and these drugs basically only have a protective effect on the gastric mucosa. Thin film layer will dilute or redissolve, unable to form a stable protective layer

[0003] Chinese Patent Announcement No. CN101411477, CN102727514 and CN101292994 provide gel protective agents made of pectin as the main component, but the conditions for pectin to form gel are more complicated and harsh, and it is difficult to form a stable gel layer in the whole digestive tract. When the gel layer redissolves or only forms a viscous protective layer, the ability to protect and isolate the mucous membrane of the digestive tract will be greatly reduced

In addition, Chinese patent announcement number CN102871117 also uses alginate as a digestive tract gel protector, but uses a calcium complexing agent, which can release calcium under acidic conditions in the stomach. However, when the gel enters the intestinal tract and is out of the acidic environment, the calcium complexing agent will recombine with calcium ions, making the gel redissolve, and the protection of the intestinal tract is only It is the protective function of the viscous sol, and loses the protective function of the gel on the intestinal mucosa