Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Stannous sulfide nanometer photo-thermal agent and preparation method thereof

A stannous sulfide, nano-light technology, applied in chemical instruments and methods, nanotechnology, nanotechnology and other directions, can solve the problem that the photothermal treatment effect of precious metal photothermal agents is not obvious, the market application of precious metal photothermal agents is limited, and the preparation process is complicated. and other problems, to achieve the effect of abundant raw materials, obvious photothermal effect, and simple preparation process

Active Publication Date: 2018-09-04
SHENZHEN UNIV
View PDF3 Cites 4 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, these photothermal agents have their own shortcomings. The photothermal properties of gold and other precious metals mainly come from the surface plasmon resonance effect, and this effect is affected by the surface morphology, size, and dielectric constant of the surrounding medium. The impact is so great that the actual photothermal treatment effect of noble metal photothermal agents is not obvious; in addition, the high price also limits the market application of noble metal photothermal agents
However, carbon materials have disadvantages such as complicated preparation process and low absorption coefficient at 808nm.

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Stannous sulfide nanometer photo-thermal agent and preparation method thereof
  • Stannous sulfide nanometer photo-thermal agent and preparation method thereof
  • Stannous sulfide nanometer photo-thermal agent and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

preparation example Construction

[0034] The second aspect of the embodiment of the present invention provides a method for preparing a stannous sulfide nano-photothermal agent, comprising the following steps:

[0035] After grinding the stannous sulfide block for 20-60 minutes, dispersing it in an organic solvent to obtain a dispersion;

[0036] Sonicate the dispersion in a water bath at 5°C-10°C for 8-12 hours to obtain an ultrasonicated dispersion;

[0037] After the ultrasonic dispersion liquid is centrifuged, the precipitate is collected and dried to obtain stannous sulfide quantum dots.

[0038] In the embodiment of the present invention, the dispersion liquid is ultrasonicated in a water bath at 10° C. for 8-12 hours.

[0039] In the embodiment of the present invention, the organic solvent includes one or both of isopropanol and nitrogen methyl pyrrolidone, and the mass concentration of stannous sulfide in the dispersion is 0.5-5 mg / mL, that is, stannous sulfide block After grinding, the mass concentr...

Embodiment 1

[0049] A preparation method of stannous sulfide nano photothermal agent, comprising the following steps:

[0050] (1) After grinding the stannous sulfide block for 30 minutes, disperse it in isopropanol to obtain a dispersion with a concentration of 1 mg / mL;

[0051] (2) Ultrasonic the above-mentioned dispersion liquid with a probe for 5 hours, the probe power of the probe ultrasonic is 360w, and the temperature of the probe is kept at 5-10°C during the ultrasonic process, and when the temperature rises during the period, use an ice pack to cool down;

[0052] (3) Ultrasonic the dispersion in a water bath for 8 hours to obtain the ultrasonic dispersion, and keep the temperature of the ultrasonic in the water bath at 5-10°C;

[0053] (4) Centrifuge the ultrasonically dispersed liquid at a speed of 15,000 rpm for 0.5 h, take the supernatant, then centrifuge the supernatant at a speed of 20,000 rpm for 0.5 h, collect the precipitate, and dry , to obtain tin sulfide quantum dots;...

Embodiment 2

[0057] A preparation method of stannous sulfide nano photothermal agent, comprising the following steps:

[0058] (1) After grinding the stannous sulfide block for 40 minutes, disperse it in nitrogen methyl pyrrolidone to obtain a dispersion with a concentration of 1 mg / mL;

[0059] (2) Ultrasonic the above-mentioned dispersion liquid with a probe for 8 hours, the probe power of the probe ultrasonic is 150w, and the temperature is kept at 10-10°C during the ultrasonic probe process, and when the temperature rises during the period, use an ice pack to cool down;

[0060] (3) Ultrasonic the dispersion in a water bath for 12 hours to obtain the ultrasonic dispersion, and keep the temperature of the ultrasonic in the water bath at 5-10°C;

[0061] (4) After centrifuging the ultrasonically dispersed liquid, centrifuge at a speed of 13,000 rpm for 1 hour, take the supernatant, then centrifuge the supernatant at a speed of 18,000 rpm for 1 hour, collect the precipitate, and dry it to...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

PropertyMeasurementUnit
Sizeaaaaaaaaaa
Login to View More

Abstract

The invention provides a stannous sulfide nanometer photo-thermal agent. The stannous sulfide nanometer photo-thermal agent comprises a stannous sulfide quantum dot, has obvious photo-thermal effects,high chemical stability and low toxicity, is prepared from abundant raw materials, has a low price, is prepared through simple processes and has a broad application prospect in the field of photo-thermal therapy. The invention also provides a preparation method of the stannous sulfide nanometer photo-thermal agent. The preparation method comprises grinding stannous sulfide blocks for 20 to 60 minutes, dispersing the powder in an organic solvent to obtain a dispersion liquid, carrying out ultrasound treatment on the dispersion liquid in a water bath at 5-10 DEG C for 8 to 12 hours to obtain the dispersion liquid subjected to ultrasonic treatment, centrifuging the dispersion liquid, collecting the precipitates and carrying out drying to obtain the stannous sulfide quantum dot. A preparationmethod of the stannous sulfide nanometer photo-thermal agent utilizes easily available raw materials, has simple processes and easily realizes large-scale production.

Description

technical field [0001] The invention relates to the technical field of nano photothermal agents, in particular to a stannous sulfide nano photothermal agent and a preparation method thereof. Background technique [0002] In recent years, photothermal therapy, as a new type of cancer therapy, has attracted widespread attention. It mainly uses photothermal agents to generate local high temperature under the irradiation of 808nm laser to kill cancer cells, with few side effects and high efficiency. [0003] At present, more photothermal agents have been studied, including precious metals such as gold, silver, and platinum, and carbon materials such as graphene, graphene oxide, and carbon nanorods. However, these photothermal agents have their own shortcomings. The photothermal properties of gold and other precious metals mainly come from the surface plasmon resonance effect, and this effect is affected by the surface morphology, size of the nanostructure, and the dielectric con...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
IPC IPC(8): A61K41/00A61K47/10C01G19/00A61P35/00B82Y40/00
CPCA61K41/0052A61K47/10A61P35/00B82Y40/00C01G19/00C01P2004/64B82Y15/00C01P2004/04
Inventor 张晗谢中建范涛健
Owner SHENZHEN UNIV
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com