Compound wintercreeper soft capsule and preparation method thereof

A technology for soft capsules and compound recipes, applied in the field of compound Fufangteng soft capsules and their preparation, can solve the problems of difficulty in promoting the absorption of raw materials, inability to cover the odor of raw materials, easy access to air, oxidation, etc., and achieve the promotion of drug efficacy. , to ensure the comfort of taste and improve the effect of immunity

Active Publication Date: 2018-09-07
GUANGXI UNIV OF CHINESE MEDICINE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Compound Fufangteng currently sells dosage forms in the market such as capsules and oral liquids. The above dosage forms are easy to contact with air and oxidize during the actual production process, resulting in the disappearance of the efficacy of the raw materials. At the same time, it is relatively difficult for hard capsules to promote

Method used

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  • Compound wintercreeper soft capsule and preparation method thereof
  • Compound wintercreeper soft capsule and preparation method thereof
  • Compound wintercreeper soft capsule and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Example

[0022] Preparation Scheme Example 1:

[0023] Preparation Process:

[0024] Step 1: Melting and heat preservation of gelatin, the melting temperature is 70℃, and the heat preservation temperature is 60℃;

[0025] Step 2: Drying and shaping of the capsule shell: Use a drying roller cage machine to shape and dry the soft capsules to remove excess water from the compressed soft capsules to maintain the appearance of the soft capsules and moderate disintegration. The water-removed capsules The water content of the finished product is under the quality standard of 10%, the water removal temperature is 60℃, and the water removal time is 6 hours;

[0026] Step 3: Weigh the raw materials according to the formula, 130 parts by weight of Fufangteng, 100 parts by weight of red ginseng, and 30 parts by weight of Astragalus root, bake at 80°C for 5 hours, dry to room temperature, mix and crush for 30 minutes, and pass through a 100 mesh sieve , Get the bulk drug powder;

[0027] Step 4: After ster...

Example

[0028] Preparation Scheme Example 2:

[0029] Preparation Process:

[0030] Step 1: Melting and heat preservation of gelatin, the melting temperature is 70℃, and the heat preservation temperature is 60℃;

[0031] Step 2: Drying and shaping of the capsule shell: use a drying roller cage machine to shape and dry the soft capsules to remove excess water from the compressed soft capsules to maintain the appearance of the soft capsules and moderate disintegration. The water-removed capsules The water content of the finished product is under the quality standard of 10%, the water removal temperature is 60℃, and the water removal time is 6 hours;

[0032] Step 3: Weigh the raw materials according to the formula, 120 parts by weight of Fufangteng, 80 parts by weight of red ginseng and 20 parts by weight of Astragalus root, bake at 80°C for 5 hours, dry to room temperature, mix and crush for 30 minutes, and pass through a 100 mesh sieve , Get the bulk drug powder;

[0033] Step 4: After steril...

Example

[0034] Preparation Scheme Example 3:

[0035] Preparation Process:

[0036] Step 1: Melting and heat preservation of gelatin, the melting temperature is 70℃, and the heat preservation temperature is 60℃;

[0037] Step 2: Drying and shaping of the capsule shell: Use a drying roller cage machine to shape and dry the soft capsules to remove excess water from the compressed soft capsules to maintain the appearance of the soft capsules and moderate disintegration. The water-removed capsules The water content of the finished product is under the quality standard of 10%, the water removal temperature is 60℃, and the water removal time is 6 hours;

[0038] Step 3: Weigh the raw materials according to the formula, 150 parts by weight of Fufangteng, 120 parts by weight of red ginseng, and 50 parts by weight of Astragalus, bake at 80°C for 5 hours, dry to room temperature, mix and crush for 30 minutes, and pass through a 100 mesh sieve , Get the bulk drug powder;

[0039] Step 4: After sterilizi...

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Abstract

The invention discloses a compound wintercreeper soft capsule, including a capsule shell of the capsule and bulk pharmaceutical chemicals with which the interior of the capsule is coated. The bulk pharmaceutical chemicals consist of the following substances: by weight, 120-150 parts of wintercreeper, 80-120 parts of red ginseng, and 20-50 parts of Astragalus membranaceus. The part inside the capsule shell is also coated with: by weight, 160-200 parts of soybean oil, 5-15 parts of beeswax, and 75-100 parts of tween. The capsule shell consists of the following substances: gelatin, glycerol and water in a ratio of 1 : 0.3-0.4 : 1, and ethylparaben used as a preservative of the capsule shell. The compound wintercreeper soft capsule has a good isolation function, thereby effectively isolating air and light, making product contents stable in the validity period, and guaranteeing effectiveness of the function. The soft capsule is accurately quantified, can promote the rapid absorption of internal bulk pharmaceutical chemicals, is safe in carrying and convenient to use, ensures the taste and comfort of the taking process, and has broad market prospects and economic benefits.

Description

technical field [0001] The invention relates to a soft capsule, in particular to a compound Fufangteng soft capsule and a preparation method thereof. Background technique [0002] Compound Fufangteng mixture is composed of red ginseng, astragalus, and Fufangteng traditional Chinese medicine. Modern pharmacological studies have shown that compound Fufangteng mixture has the effects of nourishing qi and blood, strengthening the spleen and nourishing the heart, among which Fufangteng water extract and alcohol extract have Antibacterial, prevention of thrombosis, hemostasis, sedation, improvement of body immunity, etc., so it has a wide range of applications in actual production and life. [0003] Soft capsule is a new type of health product dosage form developed after tablets, hard capsules, pills, oral liquids and other dosage forms. It has excellent light and oxygen isolation functions and good visual effects. The application of new soft capsule production technology has gre...

Claims

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Application Information

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IPC IPC(8): A61K36/481A61K9/48A61K47/44A61K47/26A61P1/14A61P7/06
CPCA61K9/4858A61K9/4866A61K36/258A61K36/37A61K36/481A61P1/14A61P7/06A61K2300/00
Inventor 赵立春唐云丽廖夏云王刚周改莲高红伟杨涛
Owner GUANGXI UNIV OF CHINESE MEDICINE
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