Preparation method of porous zinc support material for composite ZnO nanorod

Abstract

The invention relates to a preparation method of porous zinc support material for composite ZnO nanorod, and relates to a prosthesis inorganic material or a prosthesis-coated inorganic material. The method comprises the following steps of: firstly, preparing a porous zinc support material with an apparent density in the range of 1.5+/-0.1-3.5+/-0.1g/cm3 and an open-rate range of 48.4 +/-1.5-78.2+/-1.2%, which is similar to the natural bone of the human body, and preparing a ZnO nanorod in-situ on the surface of the pore wall of the porous zinc support material, in addition, obtaining the porous zinc support material of the composite ZnO nanorod. The preparation method of porous zinc support material for composite ZnO nanorod overcomes that different kinds of nitrates are needed in the process of preparing the ZnO nanorod on the surface of the substrate by the prior art, or a ZnO seed layer or a seed layer is firstly prepared on the surface of the substrate; oxygen is continuously introduce into the sodium chloride solution, and the obtained ZnO is a non-nano rod during preparation of ZnO on the surface of the zinc sheet; and the prepared degradable open-hole porous zinc and the zinc alloy biological material do not have the defects of antibacterial and sterilization performance.

Description

technical field [0001] The technical solution of the invention relates to a prosthesis inorganic material or a prosthesis coated inorganic material, specifically a method for preparing a porous zinc support material composited with ZnO nanorods. Background technique [0002] In the field of degradable biomedical metal materials, since metal zinc has a more positive standard electrode potential than metal magnesium (-0.762V SHE vs. -2.372V SHE ) and a denser oxide film (density coefficient > 1), making metal zinc have better corrosion resistance than metal magnesium in a corrosive environment. Moreover, zinc is also an essential nutrient element for the human body. Many physiological functions of the human body, such as normal growth, immune function, synthesis of DNA polymerase and transcription factors, wound healing and bone metabolism, cannot be separated from the participation of zinc. In addition, in vitro studies have shown that zinc can effectively induce Ca and...

AI Technical Summary

Problems solved by technology

[0003] At present, the problems of degradable biomedical zinc-based implants are: (1) Compared with human bones, zinc-based implants have a greater density (about 7.14g / cm 3 vs.1.8~2.1g / cm 3 ), in order to reduce the density of zinc-based implants, it has become a research and development direction to prepare them into porous zinc scaffold materials. In addition, the porous structure of zinc scaffold materials will also facilitate the in-growth of tissues and bones and make zinc-based implants Implants have better damping properties

(2) Metal zinc does not have antibacterial and bactericidal properties. When zinc-based implants are implanted in the body, bacterial infection is one of the most serious complications after surgery.

[0004] CN105088344B discloses a method for preparing a PbS Minhua ZnO nanorod array on a zinc sheet. The method uses the zinc sheet as a substrate and uses n-butylamine, lanthanum nitrate, lead nitrate and sodium sulfide as raw materials on the surface of the zinc sheet to prepare the PbS Minhua ZnO nanorod array, n-butylamine, lanthanum nitrate and sodium sulfide used in the process of preparing PbS sensitized ZnO nanorods are hazardous chemicals, lead nitrate is a hazardous chemical that is prone to explosives, and the prepared The surface of ZnO is evenly covered with a layer of toxic PbS quantum dots. The PbS-sensitized ZnO nanorod material is mainly used in solar cells, photocatalysis and other fields, and is not suitable for degradable biomedical zinc-based implants.

CN104258458B discloses degradable open-pore porous zinc and zinc alloy biomaterials and a preparation method thereof. During preparation, sodium chloride crystal particles are sintered to obtain an open-pore porous sodium chloride prefabricated structure; zinc or zinc alloy melt is poured into Place the mold cavity with sodium chloride prefabricated body for pressure seepage casting; remove the outer skin of the zinc or zinc alloy block containing the sodium chloride prefabricated body, wash with alkali, filter out sodium chloride, and obtain porous zinc and zinc alloy biomaterials , when the method prepares degradable open-pore porous zinc and zinc alloy, it is necessary to pre-sinter the sodium chloride particles at a high temperature of 650-790°C for 0.5-24 hours to obtain an open-pore porous sodium chloride prefabricated body. The pure zinc or zinc alloy block outer skin of the sodium prefabricated body is removed, and the solution used to remove sodium chloride contains 1mol / L sodium hydroxide as a strong alkaline solution, which is not only complicated in process, high in energy consumption, but also the final opening Porous zinc and zinc alloy biomaterials do not have antibacterial and bactericidal properties

[0005] In short, in the above-mentioned prior art, the methods for preparing ZnO nanorods need to use different kinds of nitrates in the process of preparing ZnO nanorods on the substrate surface, and some methods also need to prepare ZnO seed crystal layers or seeds on the substrate surface. layer; in the process of preparing ZnO on the surface of zinc sheet, it is necessary to continuously feed oxygen into the sodium chloride solution, and the obtained ZnO is non-nano-rod; the prepared degradable open-pore porous zinc and zinc alloy biomaterials do not have antibacterial and bactericidal properties. performance

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