A light-induced infiltration microfluidic chip preparation method and functionalization method

A microfluidic chip and light-induced technology, applied in the fields of biochemistry and microfluidics, can solve the problems of inability to achieve multi-functionality, and achieve the effects of flexible design, reduced production cycle and cost, and reduced preparation cycle
CN109012773BInactive Publication Date: 2021-01-05NORTHWESTERN POLYTECHNICAL UNIV
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
NORTHWESTERN POLYTECHNICAL UNIV
Publication Date
2021-01-05
Estimated Expiration
Not applicable · inactive patent

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Abstract

The invention relates to a preparation method and a functionalization method of a light-induced infiltration microfluidic chip. The surface of the chip is modified by a light-induced hydrophilic and hydrophobic material, and a hydrophilic and hydrophobic region boundary area is generated in the microstructure by ultraviolet exposure. An infiltration region can allow a fluid to pass through, and the fluid cannot enter a non-hydrophobic region subjected to Laplace pressure between columns, so that microfluidic channels are realized. By use of a photomask, exposure of different designs can be realized inside the chip, and different structures and functions of microfluidic chips are realized. Through the design of pressure-driven fluid channels and electroosmotic flow-driven fluid channels, the microfluidic chip can be erasable and can realize multifunctions on a single chip, and the production cycle and cost of design-fabrication-testing-reprocessing needed by traditional chips can be reduced. All the functions such as separation, synthesis, mixing and flow control of the microfluidic chips can be realized.
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Description

technical field

[0001] The invention belongs to the field of microfluidic technology and the field of biochemistry, and relates to a preparation method and a functionalization method of a light-induced infiltration microfluidic chip, in particular to a light-induced infiltration multi-chemical biological chip capable of realizing a single chip structure. Enclosed microfluidic chips for analytical functions and their fabrication. Background technique

[0002] The basic preparation method of the existing chip is mainly the micromachining technology of glass, hard polymers (such as polycarbonate, polymethyl methacrylate, etc.) and elastic polymers (such as polydimethylsiloxane). Among them, photolithography is the core technology of preparation. Photolithography usually includes three steps of pattern transfer (exposure), development and etching to obtain the designed microstructure on the chip. Some researchers have developed a LIGA high-resolution etching process based on p...

Claims

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