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Wood frog antimicrobial peptide gynecological gel

A technology of peptide gynecology and antibacterial peptides, applied in antibacterial drugs, antifungal agents, peptide/protein components, etc., can solve problems such as disrupting the balance of vaginal flora, difficult to cure, and stubborn gynecological diseases

Pending Publication Date: 2018-12-28
林万君
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Abuse or use of antibiotics will cause bacteria to develop drug resistance, kill a large number of beneficial bacteria, and destroy the balance of vaginal flora, resulting in vigorous growth of fungi, and gynecological diseases are stubborn and difficult to cure

Method used

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  • Wood frog antimicrobial peptide gynecological gel
  • Wood frog antimicrobial peptide gynecological gel
  • Wood frog antimicrobial peptide gynecological gel

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0045] Rana antimicrobial peptide gynecological gel is made of the following raw materials by weight percentage: 40% Rana antimicrobial peptide concentrate, 5% Cnidium chinensis extract, 5% Sophora flavescens extract, 5% Phellodendron phellodendri extract, and Comfrey extract 3%, dandelion extract 3%, centipede extract 3%, red peony extract 3%, honeysuckle extract 3%, borneol 0.3%, carbomer 1.5%, chitosan 1%, carboxymethyl cellulose Sodium 0.2%, Glycerin 15%, Ethyl Paraben 0.1%, Triethanolamine 1.5%, Sodium Hydroxide 1%, Purified Water 9.4%.

experiment example 1

[0047] Rana antibacterial peptide gynecological gel

[0048] 1. Raw materials:

[0049] Rana Antibacterial Peptide Concentrate 40% Cnidium Fructus Extract 5%

[0050] Sophora flavescens extract 5% Phellodendron phellodendron extract 5%

[0051] Comfrey Extract 3% Dandelion Extract 3%

[0052] Baibu Extract 3% Radix Paeoniae Rubra Extract 3%

[0053] Honeysuckle extract 3% borneol 0.3%

[0054] Carbomer 1.5% Chitosan 1%

[0055] Sodium Carboxymethyl Cellulose 0.2% Glycerin 15%

[0056] Ethylparaben 0.1% Triethanolamine 1.5%

[0057] Sodium hydroxide 1% Purified water 9.4%.

[0058] 2. Zone of inhibition test

[0059] The following test is to use the Rana antimicrobial peptide gynecology gel configured in Example 1.

[0060] (1) Strains

[0061] Pseudomonas aeruginosa ATCC 27853.

[0062] Escherichia coli ATCC 25922.

[0063] Staphylococcus aureus ATCC 25923.

[0064] Pseudomonas aeruginosa with clinical multi-drug resistance (the main drug-resistant names are piper...

experiment example 2

[0073] Stability test: Example 1 formulation.

[0074] Place the present invention at room temperature, 37°C, and 50°C respectively for 3 months, 2 months, and 1 month, and use the above method to do the antibacterial test every week. The bacterial species is Pseudomonas aeruginosa with clinical multidrug resistance. bacteria.

[0075]

[0076] The conclusion is that the patented product of the present invention has a stable antibacterial function through accelerated tests.

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Abstract

The invention relates to the field of bactericides, that is, wood frog antimicrobial peptide gynecological gel. The gel has the product name of wood frog antimicrobial peptide Qingrui gynecological gel and is used as an auxiliary medicine and a daily antimicrobial nursing product for treating female vaginitis. The gel is made of the following raw materials in percentage by weight: 36-44% of a concentrated wood frog antimicrobial peptide liquid, 4.5-5.5% of a fructus cnidii extract, 4.5-5.5% of a radix sophorae flavescentis extract, 4.5-5.5% of a golden cypress extract, 2.7-3.3% of a lithospermum extract, 2.7-3.3% of a dandelion extract, 2.7-3.3% of a radix stemonae extract, 2.7-3.3% of a common peony root extract, 2.7-3.3% of a honeysuckle extract and auxiliary materials. The wood frog antimicrobial peptide gynecological gel can be used as an auxiliary medicine for treating vaginitis, cervical erosion, leukorrhagia, annexitis, pelvic inflammation, endometritis and senile vaginitis.

Description

technical field [0001] The invention relates to the field of fungicides, namely the Rana antibacterial peptide gynecological gel. Commodity name: Rana antibacterial peptide Qingrui gynecological gel. As an auxiliary drug and daily antibacterial care product for the treatment of female vaginitis. Background technique [0002] Rana antibacterial peptide is a peptide substance with broad-spectrum antibacterial activity. It has an efficient and broad-spectrum killing effect on fungi, bacteria, protozoa, viruses, and common infectious bacteria. It has obvious anti-inflammatory and analgesic effects, dampness and swelling, In addition to the effect of removing putrefaction and promoting muscle growth, it also has the advantages of rapid action without residue, no drug resistance, and no toxic side effects on normal human cells. Abuse or use of antibiotics will cause bacteria to develop drug resistance, kill a large number of beneficial bacteria, and disrupt the balance of vagina...

Claims

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Application Information

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IPC IPC(8): A61K38/17A61K36/904A61K9/06A61K47/38A61P15/00A61P15/02A61P31/04A61P31/10A61K31/045
CPCA61K36/904A61K38/1703A61K47/38A61P15/00A61P15/02A61P31/04A61P31/10A61K9/0034A61K9/06A61K31/045A61K36/234A61K36/288A61K36/30A61K36/355A61K36/489A61K36/65A61K36/71A61K36/756
Inventor 林万君郑玲玲杨宝峰张丹
Owner 林万君
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