A kind of production method of conjugated linoleic acid

Abstract

The invention discloses a production method of conjugated linoleic acid, which belongs to the field of chemical synthesis methods of fats and oils. The separated short alcohol ester of linoleic acid is subjected to alkali-catalyzed isomerization, saponification, acid hydrolysis and water washing to obtain conjugated linoleic acid. The production process of the present invention can be carried out continuously and efficiently, and has the advantages of simple preparation process, mild reaction conditions, high utilization rate of raw materials, high product purity, and high product stability; low energy consumption not only reduces production cost, but also reduces Pollution to the environment, suitable for large-scale production.

Description

Technical field [0001] The present invention relates to the preparation of fatty acids, in particular a method of producing a linoleic acid, which is a chemical synthesis method of grease. Background technique [0002] Lyric acid is one of a variety of fatty acids that form fat. Lyric acid is both one of people and animals that are indispensable fatty acids, and a substance that cannot be synthesized by people and animals must be taken from food. The conjugated linoleic acid (CLA) is the isomer of linoleic acid. It is a series of linoleic acid in carbon 9, 11 or 10, 12 bonds and geometric isomers in nature. It mainly exists in ruminant cattle, sheep cream and meat products and some plants, but the content is very small. It has been studied that conjugated linoleic acid has anti-cancer, removes free radicals, enhancing the human antioxidant capacity and immunity, promoting growth development, regulates blood cholesterol and triglyceride levels, prevents atherosclerosis, promotes f...

AI Technical Summary

Problems solved by technology

[0006] Chinese patent CN107216249A discloses a preparation method of conjugated linoleic acid, which is to carry out transesterification reaction between vegetable oil and short-chain alcohol under the action of basic catalyst to prepare fatty acid short-chain alcohol ester, and then add basic catalyst to carry out isomerization Chemical reaction, saponification, acidification, and molecular distillation after low-temperature crystallization. In this preparation method, the transesterification reaction is to add a non-reusable basic catalyst to carry out the catalytic reaction. The catalyst uses a large amount and is not easy to recycle. It is costly and pollutes the environment. Secondly, the final product is obtained by molecular distillation. Due to the high boiling point of fatty acids, the high temperature during purification will increase the trans-isomer of conjugated linoleic acid, resulting in deterioration of product quality; In the production process, other by-products, such as some substances obtained by the reaction of oleic acid or palmitic acid in the starting raw material vegetable oil, will also be incorporated into the final product conjugated linoleic acid, which further leads to the purity of conjugated linoleic acid. reduce

[0007] A method for preparing conjugated linoleic acid disclosed in Chinese patent CN101440030B is to use corn germ or corn germ oil as a raw material, through the enrichment of linoleic acid under certain temperature and pressure conditions, alkali-catalyzed isomerization, ultra- The critical reaction separator and the rectifier are obtained by rectification. The whole process is carried out under the condition of supercritical carbon dioxide. The energy consumption of the reaction is high, and the product is also purified after the conjugation reaction. Consumption of processing aids also increases production costs

[0008] Chinese patent CN107312805A discloses a method for preparing polyunsaturated fatty acids of conjugated linoleic acid, which is to add lipase to the oil for enzymolysis, then enrich the polyunsaturated fatty acids by urea inclusion method, supercritical carbon dioxide extraction, alkali Catalytic isomerization to prepare conjugated linoleic acid, in which lipase is added according to the quality of oil, lipase is free in the reaction raw materials, the enzymolysis effect is poor, the utilization rate of the enzyme is low, and the enzyme recovery is difficult; the urea inclusion method will have the need The problem of a large amount of organic solvents requires more cost to remove organic solvents in the later stage