Antibacterial temperature-sensitive gel agent and preparation method thereof

Abstract

The invention discloses an antibacterial temperature-sensitive gel agent. The antibacterial temperature-sensitive gel agent comprises a percutaneous absorption accelerant which is prepared from 1-5 parts of essential oil from clove, 1-5 parts of fructus cnidii oil, 1-5 parts of cinnamon oil and 1-5 parts of lepaloine. According to the antibacterial temperature-sensitive gel agent, by adding the essential oil from clove, the fructus cnidii oil, the cinnamon oil and the lepaloine to mutually cooperate to serve as the percutaneous absorption accelerant, the four components mutually cooperate andplay a synergistic role to promote absorption of the skin to effective constituents in the gel agent, the utilization rate of the gel agent is improved, the wound healing speed is increased, the irritation is low, the cytotoxicity is low and the biocompatibility is high; the gel agent is applied in a liquid form, and macromolecular semisolid gel is formed on the medicine application part; moreover, the biosecurity is high. The invention further provides a preparation method of the antibacterial temperature-sensitive gel agent. The preparation method has the advantages that operation is simple,implementation is easy, and industrial production is facilitated.

Description

technical field [0001] The invention relates to the field of medical devices, in particular to an antibacterial temperature-sensitive gel and a preparation method thereof. Background technique [0002] Gel is a polymer or macromolecular aggregate that can absorb a large amount of solvent but is insoluble in solvent. They can quickly swell and balance in water and can maintain their shape and three-dimensional space network structure. They are also called "soft materials". The gel exists in the form of liquid or semi-solid before storage and administration (at room temperature), it can undergo sol-gel transformation under temperature changes, and can perform repair and treatment of specific parts, and has good coupling with mucosa And hydration effect, good biocompatibility, slow release and controlled release of drugs, improve bioavailability of drugs, convenient medication, wide application range, suitable for a variety of drug delivery routes, has a great role in the field...

AI Technical Summary

Problems solved by technology

However, the gels in the existing commercially available products have defects such as complicated administration, uneven application, and easy to cause secondary damage to the wound during the administration process.

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