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A composition for relieving joint pain and its medicine and application

A joint pain and composition technology, which is applied in the field of joint pain relief composition, can solve the problems of large side effects, etc., and achieve the effects of preventing degenerative changes, relieving pain, and promoting the improvement of joint activities

Active Publication Date: 2020-07-28
BY HEALTH CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Although the curative effect of these western medicines is more remarkable, but the side effect is bigger

Method used

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  • A composition for relieving joint pain and its medicine and application
  • A composition for relieving joint pain and its medicine and application
  • A composition for relieving joint pain and its medicine and application

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0030] Embodiment 1: efficacy test

[0031] 1.1 The test groups are shown in Table 1 and Table 2:

[0032] Table 1: Combination 1~combination 5 formulations

[0033]

[0034] Table 2: Experimental group settings and intervention programs

[0035]

[0036] 2.2 Effect test:

[0037] 2.2.1 Test method

[0038]A total of 195 outpatients with knee arthritis and osteoarthritis were selected and randomized into 13 groups for double-blind intervention. The average W0MAC arthritis index score and VAS pain scale were used to evaluate the improvement of clinical symptoms and the changes in the structure and function of articular cartilage in each group before and after the intervention. situation and perform statistical analysis.

[0039] VAS Pain Rating Scale: This method uses a 10cm straight line or ruler, with the words 0 and 10 indicated at both ends, and the patient is asked to mark the corresponding position of their own pain or functional limitation on the straight line ...

Embodiment 2

[0049] Example 2: Preparation of film-coated tablets

[0050] 1. Product formula

[0051]

[0052] 2. The preparation process is as follows:

[0053] 2.1 Weighing and preparing materials:

[0054] Accurately weigh D-glucosamine sulfate potassium salt, calcium carbonate, chondroitin sulfate, turmeric extract, type II collagen, non-denatured type II collagen, vitamin K2 powder, vitamin D3 powder, and croscarmellose according to the formula quantity Sodium cellulose, microcrystalline cellulose, sodium carboxymethyl cellulose, silicon dioxide, magnesium stearate, and film coating premix for later use.

[0055] 2.2 Granulation and drying

[0056] ①Preparation of 0.5% sodium carboxymethyl cellulose slurry: add water in a certain proportion to prepare sodium carboxymethyl cellulose into 0.5% sodium carboxymethyl cellulose slurry for later use.

[0057] ② Add the formula amount of D-glucosamine sulfate potassium salt, calcium carbonate, and part of croscarmellose sodium into th...

Embodiment 3

[0065] Embodiment 3: the preparation of capsule

[0066] 1. Product formula

[0067]

[0068] 2. Preparation process:

[0069] 2.1 Weighing and preparing materials:

[0070] Accurately weigh D-glucosamine sulfate potassium salt, calcium carbonate, chondroitin sulfate, turmeric extract, type II collagen, non-denatured type II collagen, vitamin K2 powder, vitamin D3 powder, pregelatinized starch, Magnesium stearate and silicon dioxide are used for standby.

[0071] 2.2 Granulation and drying

[0072] ①Preparation of 0.5% sodium carboxymethyl cellulose slurry: add water in a certain proportion to prepare sodium carboxymethyl cellulose into 0.5% sodium carboxymethyl cellulose slurry for later use.

[0073] ② Add the formula amount of D-glucosamine sulfate potassium salt, calcium carbonate, and part of croscarmellose sodium into the granulator and mix, then start the boiling granulator, and transfer the materials to be granulated to the In the fluidized granulator, the prep...

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PUM

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Abstract

The invention discloses an arthralgia relief composition, an arthralgia relief health-care product, and application of the arthralgia relief composition. The arthralgia relief composition comprises D-glucosamine sulfate potassium chloride, calcium carbonate, chondroitin sulfate, type II collagen, non-denatured type II collagen, turmeric extract, vitamin K2 powder, and vitamin D3 powder. Human feeding trials prove that the components are synergistic, allowing arthralgia to be relieved shortly, promoting joint activity improvement, and preventing further degenerative changes in articular cartilages; the arthralgia relief composition has good safety and effect, and a quick, effective scheme is provided for relief of osteoarthritis or rheumatoid arthritis pains.

Description

technical field [0001] The invention belongs to the technical field of medicines, and in particular relates to a composition for relieving joint pain, medicines and applications thereof. Background technique [0002] Arthritis generally refers to an inflammatory disease that occurs in human joints and their surrounding tissues. The clinical manifestations are joint redness, swelling, heat, pain, dysfunction and joint deformity. Severe cases lead to joint disability and affect the quality of life of patients. The etiology of arthritis is complex, mainly related to inflammation, autoimmune reaction, infection, metabolic disorder, trauma, degenerative disease and other factors. Pain is the main manifestation of arthritis, and swelling is a common manifestation of joint inflammation, which is not necessarily related to the degree of joint pain. Joint pain and edema of the tissues around the joint caused by inflammation can lead to limited joint movement. Types of arthritis incl...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K38/01A61P19/02A61P29/00A61K31/7008A61K33/10A61K31/737A61K36/9066A61K31/122A61K31/59
CPCA61K31/122A61K31/59A61K31/7008A61K31/737A61K33/10A61K36/9066A61K38/014A61P19/02A61P29/00A61K2300/00
Inventor 邱春媚殷光玲张旭光黄仪友张志超夏玉
Owner BY HEALTH CO LTD
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