Preparation method of water-soluble cannabidiol shower gel
A technology of cannabidiol and water solubility, which is applied in the field of sanitary products, can solve the problems that have not been seen in the research report of cleaning bath products, the solubility of active ingredients is reduced, and the bioavailability is reduced, so as to improve allergic reactions, increase water solubility, and save energy. The effect of raw material costs
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Embodiment 1
[0028] (1) The preparation of water-soluble cannabidiol includes the following steps:
[0029] ① Accurately weigh 100g of cannabidiol solid powder (purity above 99%) and 500g of ethanol into a 1L single-necked round bottom flask; mechanically stir for 30 minutes to fully dissolve the cannabidiol solid; cool to room temperature after the dissolution is complete.
[0030] ② Accurately weigh 300g of α-cyclodextrin and 900g of primary purified water into a 2L single-necked round bottom flask, place the flask in a 40°C water bath, and stir mechanically for 30 minutes to fully dissolve the α-cyclodextrin in the water to form Transparent solution; after the dissolution is complete, add the solution described in step ① into it at one time, and continue to stir for 10 minutes.
[0031] ③Inclusion, put the mixed solution prepared in step ② into the high-pressure homogenizer, start the high-pressure pump, and homogenize 3 times at a pressure of 35MPa and a temperature of 25°C; after the ...
Embodiment 2
[0039] (1) The preparation method of water-soluble cannabidiol is the same as in Example 1.
[0040] (2) A preparation of water-soluble cannabidiol shower gel, comprising the following steps:
[0041] ①To prepare 100 kg of product, add 30 kg of deionized water, 20 kg of sodium cocoyl glycinate and 20 kg of cocamidopropyl betaine into the reaction kettle, heat to 80°C and stir until completely dissolved.
[0042] ② Cool down to 50°C, add 0.05 kg of EDTA-2Na, 0.5 kg of xanthan gum, 3 kg of glycerin, 2 kg of allantoin, 1 kg of jojoba oil and 0.5 kg of almond oil in turn, keep stirring until completely dissolved.
[0043] ③ Cool down to 40°C, add 0.5 kg of water-soluble cannabidiol, 0.001% lavender essence, 0.01 kg of methyl paraben, stir until completely dissolved, and use citric acid to adjust the pH value of the solution to 6.5, and remove the insufficient part Make up with ionized water and stir to make it evenly mixed.
[0044] ④Stay for more than 24 hours to defoam the pro...
Embodiment 3
[0046] (1) The preparation method of water-soluble cannabidiol is the same as in Example 1.
[0047] (2) A preparation of water-soluble cannabidiol shower gel, comprising the following steps:
[0048] ①To prepare 100 kg of product, add 30 kg of deionized water, 40 kg of sodium cocoyl glycinate and 10 kg of cocamidopropyl betaine into the reaction kettle, heat to 80°C and stir until completely dissolved.
[0049] ② Cool down to 60°C, add 0.08 kg of EDTA-2Na, 2 kg of xanthan gum, 5 kg of glycerin, 3 kg of glycerin, 1 kg of jojoba oil and 1 kg of olive oil in sequence, keep stirring until completely dissolved.
[0050] ③ Cool down to 40°C, add 1 kg of water-soluble cannabidiol, 0.001% rose essence, 0.001 kg of methyl paraben, stir until completely dissolved, and adjust the pH value of the solution to 7.0 with citric acid, and remove the insufficient part Make up with ionized water and stir to make it evenly mixed.
[0051] ④Stay for more than 24 hours to defoam the product, and...
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