Microecological preparation and preparation method and application thereof
A micro-ecological preparation and compound microorganism technology, applied in the field of medicine and health care, can solve the problems of short shelf life, insufficient number of viable bacteria, unstable viable bacteria, etc., and achieve the effects of prolonging the shelf life, promoting growth and reproduction, and enhancing human resistance.
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preparation example Construction
[0032] The present invention also provides the preparation method of the above-mentioned probiotics, comprising: adding the above-mentioned prepared Rosa roxburghii extract, the above-mentioned prepared fig extract, and the above-mentioned composite oligosaccharides to the above-mentioned composite microbial bacterial powder, After fully mixing, add the above-mentioned auxiliary protection carrier and essence, and mix well again to make a microecological preparation.
[0033] The microecological preparation of the present invention can promote the growth and reproduction of probiotics by adding roxburghii extract and fig extract, so that it can always maintain a sufficient number of viable bacteria during the shelf life, prolong the shelf life, and have longer strains Vitality period, so it can better improve the intestinal micro-ecological environment and help digestion, prevent and treat intestinal diseases, treat diarrhea caused by intestinal flora imbalance, chronic diarrhe...
experiment example 1
[0038] Table 1 shows the comparison data between the probiotics prepared by using the Rosa roxburghii extract and the fig extract prepared above and the comparative examples. It should be noted that the above-mentioned preparation of Rosa roxburghii extract and fig extract is only illustrative, as long as the extracts obtained by extracting Rosa roxburghii and fig can achieve the same effect, they will not be listed one by one.
[0039] Table 1:
[0040]
[0041]
[0042]
[0043] Note: Comparative Example 1 is compared with Example 1. In Comparative Example 1, Rosa roxburghii extract and fig extract are removed, and other ingredients are prepared in the same batch as Example 1; Comparative Example 2 is relatively Contrast in Example 2, remove Rosa roxburghii extract and fig extract in Comparative Example 2, except that other ingredients are the same batch of components prepared in Example 2; Comparative Example 3 is compared with Example 3 , Remove Rosa roxburghii e...
experiment example 2
[0046] In this experimental example, the probiotics of Examples 1-3 and the examples 1-3 in Table 1 respectively correspond to the same batch, and the probiotics in Comparative Examples 1-3 and Comparative Example 1 in Table 1 -3 corresponds to the same batch.
[0047] Table 2:
[0048]
[0049]
[0050] The tolerance to gastric acid and bile salts determines whether the probiotics can colonize and exert their efficacy in vivo. According to human physiological characteristics, the stomach is the most acidic part of the entire digestive tract, its pH is usually around 3, and the passage time is generally 1-2 hours, while the concentration of bile salts in the small intestine fluctuates in the range of 0.03-0.3%. Therefore, pH 2.0 and bile salt concentration of 0.3% were used to simulate the gastrointestinal environment. It can be seen from Table 2 that the probiotics exhibit good tolerance to the gastrointestinal environment, and the viability is above 90%.
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