Decarboxylation and Decarboxylation Radical Addition of Alkyl Carboxylates of Photoactivated Electron Donor-Acceptor Complexes

Abstract

Decarboxylation and Decarboxylation Giese Radical Addition of Alkyl Carboxylates of a Photoactivated Electron Donor-Acceptor Complex: Irradiation of Hans Ester and Blue-violet Light in the Wavelength Range of 370–470 nm in a Solution Environment The reaction was carried out under an inert protective atmosphere at an equivalence ratio of 1:1–3:1–2. The photoactivated hans esters are converted into free radicals, which can undergo decarboxylation without catalyst under the attack of free radicals, and undergo Giese radical addition reactions with compounds containing alkenyl groups.

Description

technical field [0001] The invention belongs to the field of organic chemistry, and in particular relates to a decarboxylation and decarboxylation Giese radical addition reaction of an alkyl carboxylate of a photoactivated electron donor-acceptor complex. Background technique [0002] Aliphatic carboxylic acids have excellent properties such as easy operation, abundant products, and environmental friendliness, and can be widely used in green chemical synthesis. Based on this, decarboxylation and decarboxylation Giese radical addition reactions of alkyl carboxylates using aliphatic carboxylic acids as reactants have been intensively developed. At present, the method mainly used to promote the decarboxylation of carboxylate to form a carbon-carbon bond structure is mainly: using a transition metal complex as a catalyst under high temperature reaction conditions to catalyze the reaction of the reactants. However, the catalysts used for the above purposes are often expensive, w...

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Problems solved by technology

However, the catalysts used for the above purposes are often expensive, which greatly increases the cost of raw materials in production and reduces the economic benefits of production.

In addition, the catalyst mixed in the target product is often highly toxic and difficult to separate from the target product. The manufacturer must invest a lot of technical costs in order to separate the catalyst in the target product. At the same time, the remaining catalyst in the target product that cannot be separated It will also reduce the purity of the target product and affect the quality of the product

For example, the decarboxylation product obtained by the Barton decarboxylation reaction is inevitably mixed with tin compounds and mercaptans. These substances have high toxicity and pungent odor, which introduce safety hazards to the product. The cost of separating these substances from the product Occupies a large proportion of the product output cost

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