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Antibacterial inflammation-elimination composition as well as preparation method and application thereof

A composition and the technology of chrysanthemum extract, which are applied in the field of biomedicine, can solve the problems of destroying the balance and restriction of vaginal flora, large toxic and side effects, and repeated illnesses, and achieve excellent antibacterial effect, low irritation, and excellent antibacterial effect Effect

Inactive Publication Date: 2019-12-24
GUANGZHOU SHENNONG BIOLOGICAL TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] Most antibacterial products currently on the market for vaginal cleaning are drugs containing chemical ingredients, which can achieve significant antibacterial effects, but the side effects of long-term use of chemical drugs: A, large toxic and side effects, and bacteria are prone to drug resistance; B , while killing the germs, it also kills the beneficial vaginal bacilli, destroys the balance and restriction relationship between the vaginal flora, and reduces local resistance; thus leading to aggravation of the disease and recurrence of the disease

Method used

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  • Antibacterial inflammation-elimination composition as well as preparation method and application thereof

Examples

Experimental program
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Effect test

Embodiment 1

[0026] The antibacterial and anti-inflammatory composition of pomegranate peel, honeysuckle and chrysanthemum comprises the following raw materials in parts by weight: 50 parts of pomegranate peel extract, 50 parts of honeysuckle flower extract, and 50 parts of chrysanthemum flower extract.

[0027] The preparation method comprises the following steps:

[0028] The pomegranate peel, honeysuckle and chrysanthemum are extracted to obtain a mixed extract A; the medicinal materials of the pomegranate peel, honeysuckle and chrysanthemum are respectively extracted by a heating and reflux extraction method.

[0029] Pomegranate peel extract: Mix the raw materials of pomegranate peel and drinking water at a mass volume ratio of 1:5, heat and reflux for extraction for one hour, filter through a 100-mesh sieve, collect the filtrate, repeat the operation three times, and combine the filtrate; Concentrate under reduced pressure under the condition of 0.07MPa~0.090MPa to obtain the water-e...

Embodiment 2

[0032] The antibacterial and anti-inflammatory composition of pomegranate peel, honeysuckle and chrysanthemum is prepared into an effervescent tablet preparation, including the following raw materials in parts by weight: 50 parts each of pomegranate peel, honeysuckle and chrysanthemum extract; 10 parts of tartaric acid; 10 parts of sodium bicarbonate; sodium carboxymethyl starch (CMS-Na) 8 parts; microcrystalline cellulose (MCC-102) 9 parts; lactose 27 parts; magnesium stearate 1 part.

[0033] The preparation method comprises the following steps:

[0034] S1. Extracting pomegranate peel, honeysuckle and chrysanthemum to obtain a mixed extract A; extracting the mixture of pomegranate peel, honeysuckle and chrysanthemum by heating and refluxing extraction.

[0035] The specific operation of extracting pomegranate peel is as follows: mix the raw material of pomegranate peel and drinking water at a mass volume ratio of 1:5, heat and reflux for extraction for one hour, filter thro...

Embodiment 3

[0040] The antibacterial and anti-inflammatory composition of pomegranate peel, honeysuckle and chrysanthemum is prepared into an ointment preparation, including the following raw materials in parts by weight: 10 parts each of pomegranate peel, honeysuckle and chrysanthemum extract, 18 parts of petrolatum, 20 parts of beeswax, 16 parts of liquid paraffin, 1 part of borneol, 15 parts of tea seed oil.

[0041] The preparation method comprises the following steps:

[0042] S1. Extract pomegranate peel, honeysuckle, and chrysanthemum to obtain mixed extract A; the mixture of pomegranate peel, honeysuckle, and chrysanthemum is extracted by heating and reflux extraction.

[0043] The specific operation of heating and refluxing the mixture of pomegranate peel, honeysuckle and chrysanthemum is as follows: mix the raw materials of pomegranate peel, honeysuckle and chrysanthemum at a ratio of 1:1:1, and mix the raw materials of pomegranate peel, honeysuckle and chrysanthemum with drinki...

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Abstract

The invention discloses an antibacterial inflammation-elimination composition which consists of 10-100 parts by weight of a pomegranate bark extract, 10-100 parts by weight of a honeysuckle extract and 10-100 parts by weight of a chrysanthemum extract. The pure traditional Chinese medicine preparation which is prepared by using an advanced process through refining is safe and reliable, and treatment effects can be taken into play gently and continuously. Various animal tests and in-vitro antibacterial tests show that the treatment effects are definite, and compared with a product sold in the market, the composition has an in-vitro antibacterial effect prior to that of the product sold in the market at present.

Description

technical field [0001] The invention relates to the technical field of biomedicine, and more specifically, to an antibacterial and anti-inflammatory composition, a preparation method and application thereof. Background technique [0002] Vaginitis, a group of conditions that cause vulvovaginal symptoms such as itching, burning, irritation, and abnormal discharge. Due to the characteristics of anatomical tissue, the vagina of normal healthy women has a natural defense function against the invasion of pathogens. For example, the closure of the vaginal opening, the close contact of the front and rear walls of the vagina, the hyperplasia of vaginal epithelial cells and keratinization of surface cells under the influence of estrogen, and the balance of vaginal pH balance inhibits the reproduction of pathogens that adapt to alkaline, while the cervical mucus appears Alkaline, when the natural defense function of the vagina is destroyed, pathogens are easy to invade, leading to va...

Claims

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Application Information

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IPC IPC(8): A61K36/355A61P15/02A61P31/04
CPCA61K36/185A61K36/287A61K36/355A61P15/02A61P31/04A61K2300/00
Inventor 李莹雪
Owner GUANGZHOU SHENNONG BIOLOGICAL TECH
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