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41results about How to "Improve anti-inflammatory and antibacterial effect" patented technology

Artificial lens with drug sustained release micro-capsules inlaid on loop and manufacturing method thereof

The invention relates to an artificial lens with drug sustained release micro-capsules inlaid on a loop and a manufacturing method of the artificial lens. The artificial lens can suppress microbial infection and the like after a cataract surgery effectively. The manufacturing method is simple, mature and practical. The artificial lens with the drug sustained release micro-capsules inlaid on the loop is characterized in that at least one loop hole is formed in the loop, and the sustained release micro-capsules are inlaid in the loop holes. The manufacturing method comprises the following steps: 1) the loop holes are carved in the loop of the artificial lens, ultrasonic cleaning is conducted to the holes and the holes are reserved; 2) inner cores of the micro-capsules are prepared; 3) a plurality of layers of nanometer films are arranged on the inner surface layer of the inner core of each micro-capsule in a self-assembly mode; 4) the obtained micro-capsules are stored in cold, vacuum drying is conducted to the micro-capsules so that dry capsules without water are obtained; 5) the dry micro-capsules are inlaid in the loop holes of the artificial lens under a microscope, and therefore the artificial lens with the drug sustained release micro-capsules inlaid on the loop is manufactured; and then ethylene oxide sterilization and sealed package are conducted.
Owner:SECOND AFFILIATED HOSPITAL ZHEJIANG UNIV COLLEGE OF MEDICINE

Anti-inflammatory sterilizing essential oil composition, and preparation method and application thereof

The invention provides an anti-inflammatory sterilizing essential oil composition. Through combined action of tea tree essential oil, lavender essential oil, folium artemisiae argyi essential oil, peppermint essence oil, rosemary essential oil and thyme essential oil, the effects of improving inflammation treatment and bacteria resistance, prolonging volatilization time and enhancing durability ofessential oil are achieved synergistically. According to the essential oil composition provided by the invention, on the one hand, phenolic substances in the components enter cell membranes or cell walls of microorganisms, so that a cell membrane function is affected, leak of cellular content is promoted, cell structures are destroyed, and death of the microorganisms is caused; and on the other hand, terpenoids in the components inhibit microbial metabolism and inhibit reduced coenzyme and other enzymes, so that microorganism metabolism disorder is caused, and a bacteriostatic effect is achieved. According to the essential oil composition provided by the invention, synergistic interaction is achieved through interaction of the components, so that inhibition and killing efficiency on bacteria are effectively improved, meanwhile, action time of the essential oil can be prolonged, and thus the anti-inflammatory and anti-bacterial effect lasts long.
Owner:HUBEI CHUANGJIE BIOLOGICAL TECH CO LTD

Acne removal traditional Chinese medicine composition as well as preparation method and application thereof

The invention provides an acne removal traditional Chinese medicine composition. The acne removal traditional Chinese medicine composition is prepared by mixing extract liquid of the following components in parts by weight and ecologic nutritional solution, 20 to 50 parts of radix scutellariae, 15 to 40 parts of radix et rhizoma rhei, 8 to 30 parts of radix sophorae flavescentis, 5 to 25 parts ofgalla chinensis, 3 to 10 parts of licorice roots and 0 to 5 parts of dry gingers. The invention also provides a preparation method of the acne removal traditional Chinese medicine composition. The preparation method comprises the following steps: heating, refluxing and extracting by using ethanol, filtering, centrifuging filtrate, dissolving, performing membrane separation treatment, adding ecological nutritional solution and the like; on one hand, the radix scutellariae alcohol extract is obtained by virtue of the ethanol refluxing extraction, and the antibacterial and anti-inflammation effect is good; and on the other hand, by adding the ecological nutritional solution, acne propionibacteria causing the acnes can be prevented, the regeneration state of saprophytic bacteria is optimized,the micro ecology of the skin is regulated, and the balance of the biologic flora is maintained. The invention also provides application of the traditional Chinese medicine composition in cosmetics. The acne removal traditional Chinese medicine composition is non-irritating to the skin.
Owner:科丽思化妆品(上海)有限公司

Traditional Chinese medicine composition with bacteriostatic, anti-inflammatory, hemostatic and analgesic effects and preparation method thereof

The invention discloses a traditional Chinese medicine composition with bacteriostatic, anti-inflammatory, hemostatic and analgesic effects and a preparation method thereof. According to the method, apithecellobium clypearia extract and a lamiophlomis rotata extract are used as raw materials; poly(lactic-co-glycolic acid) PLGA, vitamin E polyethylene glycol succinate TPGS and poloxamer are used as a drug-loaded matrix. The preparation method comprises the following steps: mixing raw medicinal materials with the drug-loaded matrix to form an oil phase and an oil-in-water phase, performing probe ultrasonic emulsification to obtain a nano-suspension, and adding carbomer, collagen tripeptide, oat beta-glucan and propylene glycol as a gel matrix to obtain traditional Chinese medicine composition nanogel. The prepared traditional Chinese medicine composition nanogel has the particle size of 120 nm-260 nm, has good drug loading capacity, obviously improves the solubility and bioavailabilityof hydrophobic drugs, inhibits bacteria, diminishes inflammation, stops bleeding and relieves pain, and is definite in curative effect.
Owner:江西杏林白马药业股份有限公司

Compound norfloxacin composition and preparation method

The invention discloses a compound norfloxacin composition and a preparation method. The composition comprises the following components: norfloxacin, frankincense, fructus setariae germinatus, medicated leaven, dried ginger, Luying, largehead atractylodes rhizome, morinda root, red dates, leaves of officinal magnolia bark, bitter orange, sodium carboxymethyl starch, low-substituted hydroxypropyl cellulose, starch, sucrose ester and aerosil. The preparation method comprises the steps of material preparation, extraction of active ingredients of active pharmaceutical ingredients of traditional Chinese medicines, granulation, drying, granule integration and tabletting/encapsulation. The composition has the beneficial effects that the medicines have obvious synergistic effects, not only have the effect of improving the bacteriostatic and antiphlogistic effects of norfloxacin but also have the effect of overcoming the side effects of norfloxacin on gastrointestinal tracts and have the effects of tonifying the spleen and nourishing the stomach, thus improving the compliance of patients; the composition is reasonable in usage amount of the medicinal auxiliary materials and usage amount selection and is simple in formula; the preparation process is reasonable and stable, has good reproducibility and easily achieves industrial production; the cost is low, thus being beneficial to reducing the product price.
Owner:QINGDAO HAIZHIYUAN INTELLIGENT TECH

Hyaluronic acid-containing vola repairing and moisturizing spray and preparation method thereof

The invention discloses a hyaluronic acid-containing vola repairing and moisturizing spray and a preparation method thereof. The hyaluronic acid-containing vola repairing and moisturizing spray is prepared from super-active sodium hyaluronate, medium and low molecular weight sodium hyaluronate, zinc hyaluronate, low molecular weight zinc hyaluronate, centella asiatica extract, vitamins, amino acids, a preservative and purified water. The preparation method of the spray comprises the following steps: weighing the components, dissolving, filtering and filling into a spray bottle to prepare the water-soluble spray. The spray can be used for foot chapped symptoms commonly existing in life, and has the effects of foot moisturizing, bacteriostasis, inflammation diminishing and repairing. Super-active sodium hyaluronate, medium and low molecular weight sodium hyaluronate, zinc hyaluronate, low molecular weight zinc hyaluronate and centella asiatica are combined according to a certain mass ratio and can interact with one another, so that a synergistic effect is achieved, and the antibacterial and anti-inflammatory effects of the hyaluronic acid-containing vola repairing and moisturizing spray are remarkably improved.
Owner:BLOOMAGE BIOTECHNOLOGY CORP LTD +1

Compound norfloxacin sustained release tablet and preparation method

The invention discloses a compound norfloxacin sustained release tablet and a preparation method. The sustained release tablet comprises the following components: norfloxacin, frankincense, fructus setariae germinatus, medicated leaven, dried ginger, Luying, largehead atractylodes rhizome, morinda root, red dates, leaves of officinal magnolia bark, bitter orange, sodium alginate, starch, polysorbate and aerosil. The preparation method comprises the steps of material preparation, extraction of active ingredients of traditional Chinese medicines, granulation, drying, granule integration and tabletting. The sustained release tablet has the beneficial effects that the medicines have obvious synergistic effects, not only have the effect of improving the bacteriostatic and antiphlogistic effects of norfloxacin but also have the effect of overcoming the side effects of norfloxacin on gastrointestinal tracts and have the effects of tonifying the spleen and nourishing the stomach, thus improving the compliance of patients; the efficacy is maintained, the frequency of release to peak of the medicines is reduced and the visceral organs of the patients are also protected to a certain extent by controlling the concentrations of the medicines in blood.
Owner:QINGDAO HAIZHIYUAN INTELLIGENT TECH

A kind of natural medicinal composition for external use and preparation method thereof for preventing and treating acne

The invention discloses an external use type natural medicine composition for preventing and treating acne. The external use type natural medicine composition is prepared from the following componentsof herba sophorae alopecuroidis extract, herba nasturtii officinale extract and flos spiraeae ulmariae extract; or aloperine, sophoridine, herba nasturtii officinale extract, and flos spiraeae ulmariae extract. The invention also provides a preparation method of the external use type natural medicine composition. The external use type natural medicine composition has the advantages that the composition is a natural medicine extract or a single compound composition, the natural property is good, the side effect is small, the easiness in production of medicine resistance is avoided, and the like; proofed by test, the bacteria-inhibiting and anti-inflammatory functions are better, and the growth, proliferation and inflammation of propionibacterium acnes , staphylococcus epidermidis and staphylococcus aureus are inhibited; the effects of inhibiting bacteria, resisting inflammatory and inhibiting grease excretion are realized, and the irritation to skin is smaller after using for a long time; the aloperine and sophoridine components have good synergistic function, the better bacteria-inhibiting and anti-inflammatory treatment effects are realized, and the application prospect is betterin acne treatment.
Owner:NINGXIA VOCATIONAL TECH COLLEGE

External preparation for carrying out insect killing and sterilization on household pets and preparation process thereof

The invention provides an external preparation for carrying out insect killing and sterilization on household pets. The external preparation comprises the following components: tetramethrin, beta-cypermethrin, permethrin, a synergist, an emulsifier, alcohol, an antioxidant, a hair protection agent, artemisia apiacea essential oil, tea polyphenol, an aromatic, a defoaming agent and water. The artemisia apiacea essential oil and the tea polyphenol are added as components during preparation, the characteristics of the artemisia apiacea essential oil and the tea polyphenol are utilized, the anti-inflammatory and antibacterial capabilities of the pets are improved, the immunity of the pets is enhanced, and maintenance on the pets is implemented; meanwhile, a special preparation tank is adopted technologically, a supporting seat is arranged outside the preparation tank, up-and-down movement of a tank body is implemented by utilizing sliding connection between the supporting seat and the tank body, a stirring rod rotates to carry out stirring on raw materials, a rotating plate can implement horizontal movement in the tank body and then is matched with external lifting so as to improve the uniform mixing efficiency of preparation; and meanwhile, the sealing performance between a tank cover and the tank body is enhanced through a locking assembly so as to reduce external pollution in the preparation process.
Owner:HENAN HEIMA ANIMAL PHARM CO LTD
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