The invention discloses American cockroach freeze-dried powder based pre-essence which is prepared from the following raw materials: American cockroach freeze-dried powder, fructus anrederae cordifoliae extract, common perillae seed extract, caulis dendrobii officinale extract, Chinese yam extract, fresh dried rehmannia root extract, kudzu vine root extract, ganoderma lucidum extract, chamomile flower extract, flower-de-luce, sweet osmanthus flower, butterflybush flower, rose, honeysuckle flower, glycerol, alcohol and deionized water. The invention further discloses a preparation method for American cockroach freeze-dried powder based pre-essence. The American cockroach freeze-dried powder based pre-essence can maintain genes from source, can promote and improve synthesis of proteins, improves skin microcirculation, improves the skin dull-yellow problem and the pachulosis problem, has the effects of shrinking enlarged pores, homogenizing skin color, concealering, whitening, resisting inflammatory, wrinkles and ageing, screening sunlight, and the like. After the American cockroach freeze-dried powder based pre-essence is used, skin changes to be tender and smooth in touch, skin color is improved, skin quality is remarkably improved; and moreover, raw materials are basically pure natural traditional Chinese medicines, have excellent corrosion resistance, do not need to add any preservative, do not harm skin, and are high in safety coefficient.