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Dihydromyricetin-containing toothpaste with functions of whitening and repairing teeth and preparation method thereof

A technology of dihydromyricetin and tooth whitening, applied in dentistry, oral care, pharmaceutical formulations, etc., can solve the problems of gum and tooth body damage, enzymatic effect and insufficient technical maturity, so as to reduce the impact and improve phytic acid Chelate descaling function, improve the effect of anti-oxidation

Inactive Publication Date: 2020-02-18
庐山百草堂生物制药有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] The present invention improves on the prior art. There are three main whitening principles of the existing tooth whitening and repairing toothpaste: physical method to increase the rubbing strength of toothpaste, chemical method to acid-etch the dirt layer or direct peroxide bleaching and biological enzyme method to digest stains Among them, the first two are the ones with obvious clinical curative effect, especially the chemical method has the best clinical effect and the most citations, while the latter enzymatic method has not enough effect and technical maturity
However, the existing most effective chemical whitening toothpaste removes part of the acquired stain film, and it will cause corrosion to the glaze of the tooth itself even deeply, forming a new rough surface with free radicals and holes. If you dispose of it at this time Not good, it is easier to acquire foreign substances and pigments, form new stains and scale films, and rebound quickly, and the damage to the gums and tooth bodies will be more serious due to repeated use

Method used

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  • Dihydromyricetin-containing toothpaste with functions of whitening and repairing teeth and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0024] A tooth whitening and repairing toothpaste containing dihydromyricetin consists of 0.1 wt% dihydromyricetin with a purity of more than 98%, 2 wt% sodium phytate, 0.02 wt% beta-1,3 glucan, glycyrrhizic acid Dipotassium 0.2wt%, Zinc Citrate 0.3wt%, Toothpaste Friction Agent Calcium Carbonate 30wt%, Adhesive Thickener Xanthan Gum 0.6wt%, Carboxymethylcellulose Sodium 0.2wt%, Humectant Glycerin 3wt%, Sorbet Alcohol (70% aqueous solution) 52wt%, foaming agent sodium lauryl sulfate 2wt%, sodium saccharin 0.25wt%, preservatives and essence 2wt%, the rest is pure water.

[0025] Add purified water into the pre-dissolving pot, add water-soluble raw materials such as dihydromyricetin and sodium phytate into the pre-dissolving pot, stir and mix the solution to form an aqueous solution; add toothpaste abrasive to the pre-mixed powder pot, and disperse evenly Prepare the powder; pump the moisturizing agent into the pre-dispersion pot, disperse the adhesive thickener into the pre-dis...

Embodiment 2

[0027] A tooth whitening and repairing toothpaste containing dihydromyricetin consists of 0.03wt% dihydromyricetin with a purity of more than 98%, 2wt% sodium phytate, 0.04wt% beta-1,3 glucan, and glycyrrhizic acid Dipotassium 0.3wt%, Zinc citrate 0.5wt%, Toothpaste abrasive agent calcium dihydrogen phosphate 25wt%, Hydrated silica 7wt%, Adhesive thickener xanthan gum 0.7wt%, Seaweed extract 0.3wt%, Humectant glycerin 2wt%, sorbitol (70% aqueous solution) 48wt%, foaming agent sodium lauryl sulfate 2wt%, sodium saccharin 0.25wt%, paeonol 0.2wt%, preservatives and essence 2wt%, and the rest is pure water.

[0028] Add purified water into the pre-dissolving pot, add water-soluble raw materials such as dihydromyricetin and sodium phytate into the pre-dissolving pot, stir and mix the solution to form an aqueous solution; add toothpaste abrasive to the pre-mixed powder pot, and disperse evenly Prepare the powder; pump the moisturizing agent into the pre-dispersion pot, disperse the ...

Embodiment 3

[0030] A tooth whitening and repairing toothpaste containing dihydromyricetin consists of 0.2wt% dihydromyricetin with a purity of more than 98%, 3wt% sodium phytate, 0.02wt% beta-1,3 glucan, glycyrrhizic acid Dipotassium 0.2wt%, zinc citrate 0.3wt%, toothpaste abrasive aluminum hydroxide 25wt%, hydrated silicon dioxide 5wt%, adhesive thickener xanthan gum 0.6wt%, sodium carboxymethylcellulose 0.2wt% , moisturizing agent polyethylene glycol 3wt%, sorbitol (70% aqueous solution) 50wt%, foaming agent sodium lauryl sulfate 2wt%, sodium saccharin 0.25wt%, chlorella powder 2wt%, preservatives and essence 2wt% %, the rest is pure water.

[0031] Add purified water into the pre-dissolving pot, add water-soluble raw materials such as dihydromyricetin and sodium phytate into the pre-dissolving pot, stir and mix the solution to form an aqueous solution; add toothpaste abrasive to the pre-mixed powder pot, and disperse evenly Prepare the powder; pump the moisturizing agent into the pre-...

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Abstract

The invention discloses dihydromyricetin-containing toothpaste with functions of whitening and repairing teeth and a preparation method thereof. The preparation method comprises the following steps: adding purified water into a pre-dissolving pot, adding water-soluble raw materials, such as dihydromyricetin, sodium phytate and the like, into the pre-dissolving pot, and stirring the mixed solutionto form an aqueous solution; adding a toothpaste abrasive into a pre-mixed powder pot, and performing uniform dispersing to prepare a powder material; pumping a humectant into a pre-dispersing pot, dispersing an adhesive thickening agent into the pre-dispersing pot, feeding materials into a vacuum paste maker, performing homogenizing, grinding and uniform stirring, and performing cooling; adding afoaming agent into the vacuum paste maker, stirring the mixture at medium speed until the mixture is homogenous, feeding other substances into the mixture, and performing stirring; filling paste after the paste is qualified in sampling and inspection to obtain the toothpaste with functions of whitening and repairing teeth. The toothpaste can be used for quickly repairing and removing new surfacecharges outside stains dirt membranes, so that the normal balance of the tooth surface can be maintained, harmful flora can be inhibited, and secondary dyeing factors, such as dietary and other external colors, can be prevented.

Description

technical field [0001] The invention relates to the field of toothpaste, in particular to a dihydromyricetin-containing tooth whitening and repairing toothpaste and a preparation method thereof. Background technique [0002] In the oral environment, tooth surface stains are often mixed with extrinsic stains on the tooth surface, and their formation is based on acquired pellicles. The salivary acquired membrane is formed by the selective adsorption of glycoproteins in saliva to the tooth surface. It is a thin layer of acellular, unstructured, homogeneous organic membrane with a thickness of about several microns. Acquired films contain substances such as amino acids, proteins, carbohydrates and lipids, and can be formed on the surfaces of tooth surfaces and fillings, calculus, restorations and appliances in the oral cavity through the action of ionic charges. After the acquired film is formed, bacteria and dietary pigments such as tea, coffee and soy sauce can adhere to it t...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K8/55A61K8/49A61K8/365A61K8/63A61K8/73A61Q11/00
CPCA61K8/498A61K8/73A61K8/63A61K8/365A61K8/55A61Q11/00
Inventor 吴玉初郭茂军
Owner 庐山百草堂生物制药有限公司