Ten-medicine Xiang Lu capsule, preparation method thereof and ginsenoside content analysis method

Abstract

The invention discloses a ten-medicine Xiang Lu, a preparation method thereof and a ginsenoside content analysis method, and belongs to the technical field of traditional Chinese medicine formulas. The capsule gives full play to the values of the traditional Chinese medicines, has the effects of soothing liver-qi stagnation, softening hardness to dissipate stagnation and the like, the pharmacodynamic material basis of ginseng is ginsenoside which has an adjusting effect on the neuroendocrine function of the pituitary-gonad axis and can excite the pituitary to secrete gonadotropin, promote biosynthesis of DNA and protein synthesis related zymoprotein and increase the gonad activity. Through the two-way regulation effect on the pituitary-gonad axis, the positive and negative feedback functions of neuroendocrine are balanced so as to achieve the purpose of reducing estradiol which is abnormally increased, and mammary gland cell proliferation controlled by ovarian hormone is inhibited; andinternal components of traditional Chinese medicines are selected as internal standards in a quantitative analysis of multiple components by single marker, and the content of the to-be-detected components is calculated by measuring relative correction factors (RCF) between the internal standards and other to-be-detected components, so that the use amount of reference substances is reduced, and the cost is saved.

Description

technical field [0001] The invention belongs to the technical field of traditional Chinese medicine formulas, and in particular relates to a traditional Chinese medicine for regulating mammary gland hyperplasia and a method for verifying its efficacy. Background technique [0002] Mammary gland hyperplasia (Hmg) belongs to the category of "breast pain" in traditional Chinese medicine. The basic cause of the occurrence and development of this disease is the dysfunction of the three viscera - liver depression, spleen deficiency, and kidney deficiency. The external manifestations are phlegm coagulation, qi stagnation, and blood stasis. The main ingredients of the existing therapeutic prescriptions are Bupleurum, Fritillaria, Angelica, Mint, Poria, Green Bark, Atractylodes Rhizome, Prunella vulgaris, Radix Paeoniae Alba, Curcuma, Radix Glycyrrhiza, Coptidis Rhizoma, Scutellaria Baicalensis, Pangolin, Turtle Shell, Cortex Moutan, Rhizoma Chuanxiong Salvia miltiorrhiza, Mitsubishi...

AI Technical Summary

Problems solved by technology

The main ingredients of the existing therapeutic prescriptions are Bupleurum, Fritillaria, Angelica, Mint, Poria, Green Bark, Atractylodes Rhizome, Prunella vulgaris, Radix Paeoniae Alba, Curcuma, Radix Glycyrrhiza, Coptidis Rhizoma, Scutellaria Baicalensis, Pangolin, Turtle Shell, Cortex Moutan, Rhizoma Chuanxiong Salvia miltiorrhiza, Mitsubishi, honeysuckle, even wing, curcuma, coix seed, and dried ginger. The original formula of Taohong Siwu Decoction adopts the method of promoting blood circulation, and on the basis of the main prescription, additional medicines such as Bupleurum, Angelica, Chuanxiong, or the method of dispelling stagnation and relieving pain are self-made prescriptions. Medicines include Radix Bupleurum, Curcuma Curcuma, Radix Paeoniae Alba, Corydalis Corydalis, Prunella vulgaris, Oyster forge and Fritillaria japonicus; There are many types of related Chinese medicine components for oral administration and external application, but the healing effect is not obvious, or the cycle is long; therefore, in the prior art, there is an urgent need for A new technical solution to solve this problem

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