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Antiseptic system for infant wet tissue immersion liquid and preparation method thereof

A technology of baby wipes and soaking liquid, which is applied in the field of antibacterial sanitary products, can solve the problems of low safety, toxic and side effects, bad sour taste, etc., and achieve the effect of broad market prospects, high safety performance, and wide spectrum of antiseptic bacteria

Inactive Publication Date: 2020-04-07
FUJIAN HENGAN HLDG CO LTD +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Sodium benzoate and potassium sorbate are compounded in the conventional food-grade wet wipe soaking liquid antiseptic system. In order to achieve stable antiseptic performance, the system requires the pH value to be controlled at 4.0-4.5, and the characteristic odor of these two raw materials leads to wet wipes The product has a strong bad sour taste and is easily rejected by infants and young children when used. At the same time, due to the unstable structure of potassium sorbate, wet wipes are prone to yellowing
[0003] In addition, when the wet wipes are used for wiping, the soaking liquid of the wet wipes will remain on the baby's skin. The toxic side effects and irritation of the preservatives compounded by sodium benzoate and potassium sorbate will cause damage to the delicate skin of infants.
At the same time, wet wipes contain a lot of water, and there are problems of bacterial contamination and bacterial reproduction during storage and use, with low safety and poor antibacterial effect

Method used

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  • Antiseptic system for infant wet tissue immersion liquid and preparation method thereof
  • Antiseptic system for infant wet tissue immersion liquid and preparation method thereof
  • Antiseptic system for infant wet tissue immersion liquid and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0031] A kind of preservative system used for soaking liquid of baby wipes, comprising the following components by weight ratio: ε-polylysine 0.05%, lauroyl arginine ethyl ester hydrochloride 0.08%, natamycin 0.01%, Dehydroacetic acid 0.01%, lactic acid 0.01%, alkyl glycoside 0.1%, glycerin 0.2%, secondary reverse osmosis water 99.54%.

[0032] The lauroyl arginine ethyl ester hydrochloride is fully reacted by L-arginine hydrochloride in a mixed solution of water and methyl ethyl ketone with lauroyl chloride at a pH of 7 and a temperature of -5°C. After the reaction is completed, adjust the pH to 5, centrifuge, and dry to obtain lauroyl arginine, then add ethanol and thionyl chloride to the lauroyl arginine to fully react, dry to obtain lauroyl arginine ethyl ester hydrochloride The crude product is obtained by adding ethyl acetate to the crude product of ethyl lauroyl arginine hydrochloride, stirring, dissolving, adjusting the pH to 5, standing still, taking the organic layer...

Embodiment 2

[0053] A preservative system for soaking liquid of baby wet wipes, comprising the following components by weight ratio: ε-polylysine 0.275%, lauroyl arginine ethyl ester hydrochloride 0.24%, natamycin 0.055%, Dehydroacetic acid 0.03%, lactic acid 0.055%, alkyl glycoside 0.3%, glycerin 0.5%, secondary reverse osmosis water 98.545%.

[0054] The lauroyl arginine ethyl ester hydrochloride is fully reacted by L-arginine hydrochloride in a mixed solution of water and ethyl acetate and lauroyl chloride at a pH of 10 and a temperature of 12°C. After the reaction is completed, adjust the pH to 7, centrifuge, and dry to obtain lauroyl arginine, then add ethanol and thionyl chloride to the lauroyl arginine to fully react, dry to obtain lauroyl arginine ethyl ester hydrochloride The crude product is obtained by adding butyl acetate to the crude product of ethyl lauroyl arginine hydrochloride, stirring, dissolving, adjusting the pH to 6, standing still, taking the organic layer, cooling t...

Embodiment 3

[0074] A kind of preservative system used for soaking liquid of baby wipes, comprising the following components by weight ratio: ε-polylysine 0.5%, lauroyl arginine ethyl ester hydrochloride 0.4%, natamycin 0.1%, Dehydroacetic acid 0.05%, lactic acid 0.1%, alkyl glycoside 0.5%, glycerin 0.8%, secondary reverse osmosis water 97.55%.

[0075] The lauroyl arginine ethyl ester hydrochloride is fully reacted by L-arginine hydrochloride in a mixed solution of water and butyl acetate and lauroyl chloride at a pH of 12 and a temperature of 30°C. After the reaction is completed, adjust the pH to 9, centrifuge, and dry to obtain lauroyl arginine, then add ethanol and thionyl chloride to the lauroyl arginine to fully react, dry to obtain lauroyl arginine ethyl ester hydrochloride The crude product is obtained by adding ethyl acetate to the crude product of ethyl lauroyl arginine hydrochloride, stirring, dissolving, adjusting the pH to 7, standing still, taking the organic layer, cooling ...

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Abstract

The invention relates to the technical field of antibacterial hygienic products, particularly to an antiseptic system for infant wet tissue immersion liquid. The antiseptic system comprises the following components, by weight: 0.05 to 0.5% of epsilon-polylysine, 0.08% to 0.4% of ethyl lauroyl arginate hydrochloride, 0.01% to 0.1% of natamycin, 0.01% to 0.05% of dehydroacetic acid, 0.01% to 0.1% oflactic acid, 0.1% to 0.5% of alkyl glycoside, 0.2% to 0.8% of glycerinum, and 97.55% to 99.54% of secondary reverse osmosis water. The preparation method is simple and convenient to process; the prepared antiseptic system is natural, safe, non-toxic, odorless, mild, non-irritant, environmentally friendly, stable in property, not prone to discoloring, good in cleaning effect, good in skin moistening effect and good in antibacterial and bacteriostatic performances.

Description

technical field [0001] The invention relates to the technical field of antibacterial sanitary products, in particular to an antiseptic system used for soaking liquid of baby wet wipes and a preparation method thereof. Background technique [0002] With the improvement of consumers' health and safety awareness, the demand for baby hand and mouth wipes is growing rapidly, and the demand for food-grade wet wipes soaked in antiseptic systems is also increasing. Sodium benzoate and potassium sorbate are compounded in the conventional food-grade wet wipe soaking liquid antiseptic system. In order to achieve stable antiseptic performance, the system requires the pH value to be controlled at 4.0-4.5, and the characteristic odor of these two raw materials leads to wet wipes The product has a strong bad sour taste, and is easily rejected by infants and young children when used. At the same time, due to the unstable structure of potassium sorbate, wet wipes are prone to yellowing. [...

Claims

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Application Information

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IPC IPC(8): A61K8/88A61K8/60A61K8/44A61K8/365A61K8/36A61K8/02A61K8/34A61Q17/00A61Q19/00A61Q19/10
CPCA61K8/88A61K8/44A61K8/602A61K8/604A61K8/365A61K8/36A61K8/345A61K8/0208A61Q17/005A61Q19/10A61Q19/005A61K2800/524A61K2800/85A61K2800/72
Inventor 蔡增雄马宏强许贵珠
Owner FUJIAN HENGAN HLDG CO LTD
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