A kind of silk fibroin/polylactic acid composite microporous membrane material and its preparation method and application

A technology of polylactic acid and microporous membranes, applied in prostheses, bandages, absorbent pads, etc., can solve the problems of reducing the biological activity of scaffold materials and limiting applications, and achieve the effects of low production cost, easy operation, and good interaction
CN110982099BActive Publication Date: 2022-07-08NANJING NORMAL UNIVERSITY
2 Cites 0 Cited by

Patent Information

Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
NANJING NORMAL UNIVERSITY
Publication Date
2022-07-08

Smart Images

  • Figure 1
    Figure 1
  • Figure 2
    Figure 2
  • Figure 3
    Figure 3
Patent Text Reader

Abstract

The invention discloses a silk fibroin / polylactic acid composite microporous membrane material and a preparation method and application thereof. In the invention, the natural silk fibroin material and the polymer polylactic acid material are compounded in a certain proportion, and the silk fibroin of different mixing proportions with a certain porosity and controllable structure and mechanical properties is prepared by a solid solvent-free gas foaming method. / polylactic acid composite microporous membrane. The preparation method of the silk fibroin / polylactic acid composite microporous membrane material in the present invention has the advantages of non-toxicity, no residue, simple operation, etc., and the organic solvent or high temperature used in the traditional stent preparation method is avoided in the micropore preparation process; And according to the pressure of the foaming gas, the pore size and porosity of the composite microporous membrane material and its thermal stability and mechanical properties can be flexibly adjusted. The preparation of the invention can obtain a safe, non-toxic and degradable composite microporous membrane material, which can be used for tissue engineering, such as skin dressings, artificial blood vessels, bone scaffolds and the like.
Need to check novelty before this filing date? Find Prior Art

Description

technical field

[0001] The invention belongs to the field of processing methods for polymer materials, and in particular relates to a silk fibroin / polylactic acid composite microporous membrane material and a preparation method and application thereof. At the same time, this method can control the pore size and porosity, thermal stability and mechanical properties of the composite membrane. The invention is suitable for research and application in the fields of tissue engineering, biomedicine, food and the like. Background technique

[0002] China is a major producer of silk, accounting for more than 70% of the world's silk production. Silk fibroin is the main component of silk. Silk fibroin not only has good biocompatibility and degradation properties, but also has the characteristics of easy processing and modification, non-toxic degradation products, and excellent physical and mechanical properties, so it has become an ideal biological Medical materials have been extens...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More