51 results about "Dermal dressing" patented technology

A skin dressing, particularly a wound dressing, comprises oxidoreductase enzyme and, optionally, peroxidase enzyme, wherein the enzyme(s) are present in hydrated condition, e.g. being present in one or more hydrated hydrogels. The dressing is used by being located on the skin of a human or animal e.g. over a wound. The oxidoreductase enzyme catalyses a reaction that produces hydrogen peroxide from an appropriate substrate, the substrate either being naturally present in body fluids and / or being supplied separately and / or being incorporated into the dressing. The currently preferred oxidoreductase enzyme is glucose oxidase. The catalyses reaction of β-D-glucose substrate to give hydrogen peroxide and gluconic acid. A mixture of oxidoreductase enzyme can undergo reaction (optionally catalysed by the peroxidase enzyme) to produce a variety of species including reactive oxygen intermediates that have antimicrobial properties and that can therefore assist in promoting wound healing.

Occlusive tissue dressings and methods including an elastomeric drape and a liquid component, at least partially cross-linked at least after one of drying and curing, suitable for application at a dressing-to-skin interface in order to create a substantially air-tight seal. The same or a different liquid component may be applied by a user at a tube-to-dressing interface in order to create a similar air-tight seal around the tube, if not occlusively sealed during its manufacture.

A skin dressing is adapted, on activation, to release one or more S-nitrosothiols, preferably S-nitroso-L-glutathione. S-nitrosothiols decompose spontaneously to produce nitric oxide, which has beneficial effects on tissues, particularly in wound healing.

The invention discloses a skin dressing and a preparation method of the skin dressing. The skin dressing takes bacterial cellulose as a base and has a skin contact surface and a conductive surface, wherein the electric conductivity of the skin contact surface is smaller than 10<-5>S / cm and the skin contact surface contains 2Mug / cm<2> to 20Mug / cm<2> of drugs; the conductive surface contains 5mg / cm<2> to 50mg / cm<2> of a conductive material, and the conductive material is one or more of a conductive macromolecular material and a conductive nano material; the skin contact surface is used for being in direct contact with a skin so as to heal a wound of the skin; the conductive surface is used for loading voltage so as to control the releasing speed of the drugs on the skin contact surface, and is also used for simulating a biological endogenous electrical field and indirectly accelerating the healing of the wound. According to the skin dressing disclosed by the invention, the conductive surface is in tight combination with the skin contact surface, so that the endogenous electrical field of the wound of the skin can be simulated very well and the skin dressing is more convenient to use.

The invention relates to a composite propellant system for demoline skin dressings, belonging to the technical field of aerosol preparation, comprising the following raw materials: propellant, latent solvent, dispersant, solubilizer, synergist, sterilization and disinfectant and Emulsifier, no freon propellant, environmentally friendly, healthy and environmentally friendly, and added a self-made synergist, with the characteristics of cationic quaternary ammonium salt type gemini surfactant, containing pyridyl quaternary ammonium salt, with high antibacterial performance, and the synergist contains hydrophilic groups (‑OH, ‑NH 2 , quaternary ammonium salt structure) and lipophilic group (alkyl long chain), showing surface activity and solubilizing effect; adding it to the projectile system can effectively disperse and uniformly adsorb the Demoline skin dressing powder, maintain The state of the system is stable, and it cooperates with the sterilizing and disinfecting agent to play a sterilizing and disinfecting effect, so that the Demoline skin dressing powder can better exert its efficacy.

The invention provides a method for manufacturing a fungus pharmaceutical composition. The method comprises steps of knocking, kneading, extension, organic solvent extraction, high temperature alkali treatment, filtering and decolouring. The method is used for extracting poly(glucosamine) cellulose from fungus cell walls. The poly(glucosamine) cellulose is different poly(glucosamine) cellulose made from a China Taiwan patent, the patent number of which is 442496, and having defects of ultralow yield, rougher cellulose, and yellowy color. The poly(glucosamine) cellulose made through the method relatively shows the advantage of high yield, fine cellulose, and white color. The prepared poly(glucosamine) cellulose can be made into an excipient. Furthermore, it is proved through experiments that the poly(glucosamine) cellulose has excellent adsorption power and moisture maintenance of a tissue fluid, and is quite suitable for being used as a skin dressing, artificial skin, or a mask.

The invention provides a 3D bionic skin dressing and a preparation method thereof, comprising interconnected hydrophilic layer fiber membranes and hydrophobic layer fiber membranes, the hydrophilic layer fiber membranes are loaded with biologically active substances, and the hydrophobic layer fiber membranes are loaded with Antibacterial substance, the surface of the hydrophilic layer fiber membrane and the surface of the hydrophobic layer fiber membrane are provided with a bionic hair follicle layer, the bionic hair follicle layer includes symmetrically arranged hair follicle holes, the hair follicle holes run through the hydrophilic layer fiber membrane, hydrophobic A layer of fibrous membrane, the pores of the hair follicle are filled with a hydrogel layer. The invention provides an efficient dressing for the treatment of burn wounds, promotes the development of the theory and application of 3D bionic skin dressings in the treatment of burn wounds, provides new ideas and approaches, and has important academic value and application prospects.