10 results about "Dermal dressing" patented technology

The invention relates to the field of biological dressings, and discloses an artificial dermis dressing as well as a preparation method and application thereof. The preparation method comprises the following steps: adding water into a container, and freezing until the water is frozen; then adding a collagen A solution, freezing and standing; continuing to add collagen B liquid, freezing and standing; continuing to add collagen A liquid, freezing and then freeze-drying; and cross-linking in a glutaraldehyde solution, and cleaning to obtain the artificial dermis dressing. The dressing provided by the invention can provide a good stent effect and promote cell migration and proliferation, and the healing rate is close to 100% after wound making. In the wound healing process, the dressing can inhibit collagen deposition, relieve inflammatory response, inhibit abnormal hyperplasia of blood vessels, inhibit excessive proliferation of fibroblasts and excessive formation of granulation tissues, and effectively prevent scar formation. The dressing can also effectively inhibit abnormal vascular hyperplasia in a wound area, and fibrosis and scar hyperplasia caused by excessive vascular hyperplasia are prevented.

The invention provides a preparation method of traditional Chinese medicine hydrogel for treating psoriasis, the hydrogel preparation is prepared from the following raw material medicines in parts by weight: 20-40 parts of PVA, 60-80 parts of borax, 20-40 parts of glycyrrhizic acid, 8-12 parts of paeoniflorin and 2-3 parts of glycerin, the hydrogel has the advantages of injectability, self-healing, stretchability and the like, can meet the requirements of skin dressing, can be tightly attached to the skin, and has a good application prospect. The separation is easy. Animal experiments prove that after being loaded with paeoniflorin, the gel has the curative effect of treating mild and moderate psoriasis, the treatment effect is remarkable, and the gel has a wide market application prospect.

The invention provides self-healing hyaluronic acid-gelatin hydrogel as well as a preparation method and application thereof, and belongs to the technical field of hydrogel. According to the invention, modifiable sites of hyaluronic acid and gelatin are modified, and phenylboronic acid modified hyaluronic acid and caffeic acid modified gelatin are chemically crosslinked through boric acid ester to form the hydrogel, so that the problem of insufficient adhesive force of hyaluronic acid and gelatin is solved, and meanwhile, the hydrogel has self-healing ability to adapt to constantly changing wound tissues; the epigallocatechin gallate is introduced into a hydrogel system, so that the hydrogel has excellent biocompatibility and good oxidation resistance at the same time. In addition, the preparation method provided by the invention is mild in reaction condition and simple and convenient to operate, and can be widely applied to the fields of skin dressings, tissue processes and the like.

The invention belongs to the technical field of skin dressings, and particularly relates to a composite hydrogel for promoting wound healing and a preparation method thereof. The composite hydrogel for promoting wound healing comprises the following raw materials in parts by weight: 60-80 parts of a composite core, 3-8 parts of I-type collagen, 8-15 parts of gelatin and 8-15 parts of an inclusion compound, a natural biological base material is adopted as a core carrier, the stability and activity of functional components are improved through a clathrate compound technology, the outer layer accurately removes inflammation stress and provides antibacterial protection through oxidation sensitivity characteristics, the middle layer directionally recruits endogenous stem cells through active peptide to activate the repair potential, and the anti-inflammatory effect is achieved. The composite inner core guides ordered deposition of collagen through a bionic structure to achieve scar repair, and the wound healing quality is remarkably improved.

The invention belongs to the technical field of skin dressings, and particularly relates to an eggshell membrane oxidation regenerated cellulose nanofiber membrane and a preparation method and application thereof. The preparation method comprises the following steps: preparing a substrate film layer from a substrate spinning solution by adopting a microfluidic gas jet spinning method; preparing the composite spinning solution on the surface of the substrate fiber membrane by adopting a microfluidic gas jet spinning method to obtain a medicine-containing membrane layer; the eggshell membrane oxidation regenerated cellulose nanofiber membrane is composed of the base membrane layer and the medicine-containing membrane layer. According to the eggshell membrane oxidized regenerated cellulose nanofiber membrane obtained by the preparation method provided by the invention, the dissolution rate and bioavailability of a medicine are remarkably improved, and the preparation method has excellent process reproducibility, so that the stability of product quality and the consistency between batches are ensured; and a reliable technical support is provided for industrial production of the eggshell membrane oxidation regenerated cellulose nanofiber membrane as a skin auxiliary material.

A cover skin wrap (100), for use with cream (20) on skin (10) is provided. The object of the invention is achieved using a sealing layer on a base layer.

The present invention discloses a multifunctional lignin hydrogel for skin dressings and a preparation method thereof. The multifunctional lignin hydrogel is prepared by first dissolving curcumin powder and alkali lignin powder in a NaOH solution in a certain proportion, slowly adding the solution dropwise to an equal volume of silver ammonia solution, and reacting at room temperature for 30 to 60 minutes. A certain amount of nudiflorin, 2.7 g acrylamide, 0.3 g acrylic acid, 3 mg N,N-methylenebisacrylamide, and 45 mg ammonium persulfate are then dissolved in a dispersion of the nanoparticles described above, stirred to form a uniform solution, and allowed to stand at room temperature for 20 to 30 minutes to obtain a nudiflorin-loaded lignin-curcumin silver nanoparticle-poly(acrylamide-acrylic acid) hydrogel. The multifunctional lignin hydrogel prepared by the present invention has multiple functions, including adhesion, antibacterial, antioxidant, and hemostatic properties. It can be used to accelerate skin wound healing and has good application prospects in skin dressings.

The invention relates to a cell membrane and a corresponding medical repair material as well as a preparation method and application thereof. The extraction method of the mesenchymal stem cell membrane comprises the following steps: carrying out cracking, ultrasonication and centrifugation on mesenchymal stem cells to obtain the mesenchymal stem cell membrane. The mesenchymal stem cell membrane can promote wound healing and damage repair of skin barriers, and can be used for preparing skin dressings, medicines for treating wound healing and cosmetics. The obtained mesenchymal stem cell membrane can be used as an effective component for treating wounds and repairing skin, a new situation that the cell membrane is applied to wound healing treatment and skin repairing is developed, and a new choice is provided for skin dressing, wound healing drugs and cosmetics.

The present invention belongs to the field of human body care technology, and discloses an oligomeric agarose sol, a preparation method, and an application thereof. The oligomeric agarose sol provided by the present invention is in the form of an opaque semi-fluid colloid or a solidified colloid at room temperature, and the degree of polymerization n is 2 to 10,000. The oligomeric agarose sol with such a special form and a specific degree of polymerization enables the polymer to have excellent moisturizing ability and the ability to promote the healing of micro-wounds. It can be used as a moisturizing ingredient in cosmetics, and has an excellent moisturizing effect regardless of whether it is in a high humidity environment or a dry environment, and has a significant effect on improving the expression of filaggrin in human keratinocytes; in the field of medical dressings, it can be used as a skin dressing to promote the healing of micro-wounds. Therefore, the oligomeric agarose sol provided by the present invention has a high application value as a bioactive substance.